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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Resof Total 400 mg/100 mg Tablet is used to treat chronic hepatitis C virus (HCV) infection. It contains sofosbuvir and velpatasvir, which stop the hepatitis C virus from spreading in the body. In some cases, this medication may cause common side effects such as headache, dizziness, fatigue, diarrhoea, vomiting, rash, lack of energy, irritability, depression, and difficulty sleeping.

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Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Resof Total 400 mg/100 mg Tablet

Resof Total 400 mg/100 mg Tablet belongs to a class of drugs called antivirals used in the treatment of chronic hepatitis C virus (HCV) infection. Hepatitis C is a severe liver infection caused by the hepatitis C virus (HCV). It is contagious (spreads from one person to another) and spreads through contact with the infected person’s blood.

Resof Total 400 mg/100 mg Tablet contains sofosbuvir and velpatasvir, which work together to stop the hepatitis C virus from spreading in your body.

Take Resof Total 400 mg/100 mg Tablet as prescribed. You are advised to take Resof Total 400 mg/100 mg Tablet for as long as your doctor has advised it based on your medical condition. In some cases, Resof Total 400 mg/100 mg Tablet may cause common side effects such as headache, fatigue, diarrhoea, vomiting, rash, lack of energy, irritability, depression, and difficulty sleeping. Most of these side effects of Resof Total 400 mg/100 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor and pharmacist about several important details. This includes any allergies to Resof Total 400 mg/100 mg Tablet or any of its components, or other medications, as well as all prescription, non-prescription, vitamins, and supplements you're currently taking. Additionally, let them know if you're using antacids, H2 blockers, and proton-pump inhibitors. It's also crucial to share any history of liver transplant, HIV, liver problems, kidney disease, or dialysis. Furthermore, inform them if you're pregnant, breastfeeding, or planning to become pregnant.

Uses of Resof Total 400 mg/100 mg Tablet

Resof Total 400 mg/100 mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.

Directions for Use

Swallow Resof Total 400 mg/100 mg Tablet as a whole with glass of water. Do not crush, break, or chew it.

Medicinal Benefits

Resof Total 400 mg/100 mg Tablet is used to treat chronic hepatitis C in adults and children over 6 years. This medication stops the hepatitis C virus from spreading in the body, helping to combat the infection and prevent further liver damage.

How Resof Total 400 mg/100 mg Tablet Works

Resof Total 400 mg/100 mg Tablet contains sofosbuvir and velpatasvir, which work by stopping the hepatitis C virus from spreading in your body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Resof Total 400 mg/100 mg Tablet

  • Headache
  • Fatigue
  • Dizziness
  • Diarrhoea
  • Vomiting
  • Rash
  • Lack of energy
  • Irritability
  • Depression
  • Staying asleep

What if I have taken an overdose of Resof Total 400 mg/100 mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may take an overdose of Resof Total 400 mg/100 mg Tablet or observe any side effects, please seek immediate medical attention.

Drug Warnings

Please tell your doctor if you are allergic to Resof Total 400 mg/100 mg Tablet or any of its components. If you are currently taking rifampicin (antibiotic), carbamazepine, phenobarbital, and phenytoin (anticonvulsants), or St. John’s wort (herbal medicine used to treat depression), avoid taking Resof Total 400 mg/100 mg Tablet . If you are currently taking or have taken amiodarone (the medicine to treat irregular heartbeats) in the last few months, inform your doctor before taking Resof Total 400 mg/100 mg Tablet , as it may result in a life-threatening slow heartbeat; your doctor may prescribe alternate treatments, or if Resof Total 400 mg/100 mg Tablet is prescribed, additional heart monitoring may be recommended. Avoid pregnancy during treatment with Resof Total 400 mg/100 mg Tablet , as it may harm the unborn baby when used in combination with ribavirin. You or your partner must use an effective birth control method during and after this treatment. However, contact your doctor immediately if you become pregnant during treatment or in the months following your treatment with Resof Total 400 mg/100 mg Tablet . Drive only if you are alert, as Resof Total 400 mg/100 mg Tablet may cause dizziness, tiredness, and reduced attention. You are advised to take proper precautions if you are infected with the hepatitis C virus to prevent the spread of infection to others.

Drug-Drug Interactions

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SofosbuvirPhenytoin
Severe
SofosbuvirPhenobarbital
Severe

Drug-Drug Interactions

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SofosbuvirPhenytoin
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Using Resof Total 400 mg/100 mg Tablet 28's together with phenytoin may significantly reduce the blood levels of Resof Total 400 mg/100 mg Tablet 28's.

How to manage the interaction:
Although there is a possible interaction between Resof Total 400 mg/100 mg Tablet 28's and Phenytoin, you can take these medicines together if prescribed by a doctor. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
SofosbuvirPhenobarbital
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Phenobarbital can drastically lower Resof Total 400 mg/100 mg Tablet 28's levels in the blood, making the medicine less effective.

How to manage the interaction:
Although taking phenobarbital with Resof Total 400 mg/100 mg Tablet 28's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without consulting a doctor.
SofosbuvirRifabutin
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Taking Rifabutin and Resof Total 400 mg/100 mg Tablet 28's may significantly reduce the blood levels of Resof Total 400 mg/100 mg Tablet 28's, which may make the medication less effective.

How to manage the interaction:
Taking Resof Total 400 mg/100 mg Tablet 28's with Rifabutin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SofosbuvirModafinil
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Coadministration of Resof Total 400 mg/100 mg Tablet 28's with Modafinil may significantly reduce the blood levels of Resof Total 400 mg/100 mg Tablet 28's.

How to manage the interaction:
Co-administration of Modafinil with Resof Total 400 mg/100 mg Tablet 28's can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms of stomach pain or swelling, Fatigue, Fever, Yellowing of skin or eyes, Dark urine, loss of appetite, or nausea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
SofosbuvirOxcarbazepine
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Oxcarbazepine can drastically lower Resof Total 400 mg/100 mg Tablet 28's levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking oxcarbazepine with Resof Total 400 mg/100 mg Tablet 28's can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
SofosbuvirCarbamazepine
Severe
How does the drug interact with Resof Total 400 mg/100 mg Tablet 28's:
Taking carbamazepine and Resof Total 400 mg/100 mg Tablet 28's together may possibly reduce the effects of Resof Total 400 mg/100 mg Tablet 28's, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Resof Total 400 mg/100 mg Tablet 28's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include plenty of vegetables and fruits, whole grains such as brown rice, oats, quinoa and barley.
  • Eat lean protein such as skinless chicken, fish, beans and egg whites.
  • Include healthy fats like avocados, olive oil and nuts.
  • Eat low-fat or non-fat dairy products to minimise damage to the liver.
  • Drink plenty of water for better processing of food by the body.
  • Avoid sugary foods such as cake, cookies, packaged baked food or soda. Also, avoid heavy salt foods.
  • Avoid foods containing saturated fats such as fried foods, fatty cuts of meat, sour cream, butter and other high-fat dairy products, as they may lead to weight gain and result in fatty liver.
  • Avoid smoking and alcohol consumption as they may increase the risk of liver damage.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Resof Total 400 mg/100 mg Tablet Substitute

Substitutes safety advice
  • Velpanat Tablet 28's

    512.50per tablet
  • Sovihep V Tablet 28's

    by AYUR

    512.50per tablet
  • Myhep All Tablet 28's

    512.50per tablet
  • Hepcvel Tablet 28's

    by AYUR

    512.50per tablet
  • Velpaclear Tablet 28's

    558.58per tablet
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Alcohol

Consult your doctor

The interaction of alcohol with Resof Total 400 mg/100 mg Tablet is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Unsafe

Resof Total 400 mg/100 mg Tablet is often used with ribavirin, which can harm an unborn baby. To avoid this risk, it's crucial to prevent pregnancy during and after treatment. If you become pregnant while taking Resof Total 400 mg/100 mg Tablet or soon after, contact your doctor right away.

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Breast Feeding

Consult your doctor

It is unknown whether Resof Total 400 mg/100 mg Tablet is excreted in human milk. Therefore, if you are a breastfeeding mother, please inform your doctor before taking Resof Total 400 mg/100 mg Tablet .

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Driving

Caution

Resof Total 400 mg/100 mg Tablet may cause dizziness, tiredness, and reduced attention in some patients. Therefore, avoid driving or operating heavy machinery if you feel dizzy, tired, or reduced attention after taking Resof Total 400 mg/100 mg Tablet .

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Liver

Consult your doctor

Please inform your doctor if you have liver impairments or problems before taking Resof Total 400 mg/100 mg Tablet .

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Kidney

Caution

Please inform doctor if you have kidney impairments/problems or if you are on kidney dialysis before taking Resof Total 400 mg/100 mg Tablet .

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Children

Caution

Resof Total 400 mg/100 mg Tablet is usually used in children 6 years of age and older. If you have any concerns regarding the use of Resof Total 400 mg/100 mg Tablet in children, please consult a doctor.

FAQs

Resof Total 400 mg/100 mg Tablet is used to treat chronic hepatitis C virus (HCV) infection.
Resof Total 400 mg/100 mg Tablet contains sofosbuvir and velpatasvir, which work by stopping the hepatitis C virus from spreading in the body.
Resof Total 400 mg/100 mg Tablet contains sofosbuvir and velpatasvir. It is used in the treatment of chronic hepatitis C virus (HCV) infection.
Hepatitis C virus infection is contagious and spreads from one person to another through contact with an infected person’s blood. Therefore, it is recommended to avoid sharing personal items or needles containing an infected person’s blood.
No, Resof Total 400 mg/100 mg Tablet is not a protease inhibitor. It is an antiviral medication used to treat hepatitis C infection.
The common side effects of Resof Total 400 mg/100 mg Tablet may include headache, fatigue, diarrhoea, vomiting, spitting up the medicine, rash, lack of energy, irritability, depression, and sleep difficulties. These side effects are usually mild and temporary. If they persist or worsen, consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - RES0542

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