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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Repace 25 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). It contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. In some cases, you may experience dizziness, tiredness, low blood pressure, weakness, anaemia (lack of blood), hyperkalaemia (high potassium levels in the blood), change in kidney function, orthostatic hypotension (low blood pressure when standing up from lying or sitting position) or hypoglycaemia (low blood sugar).
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Composition :

LOSARTAN-25MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Repace 25 Tablet

Repace 25 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart).

Repace 25 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

In some cases, you may experience dizziness, tiredness, low blood pressure, weakness, anaemia (lack of blood), hyperkalaemia (high potassium levels in the blood), change in kidney function, orthostatic hypotension (low blood pressure when standing up from lying or sitting position) or hypoglycaemia (low blood sugar). Most of these side effects of Repace 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Repace 25 Tablet or any other medicines, please tell your doctor. It is advised to complete a full course of medication and not stop taking Repace 25 Tablet suddenly, as it may cause recurring symptoms or worsen the condition. Repace 25 Tablet is not recommended for pregnant, breastfeeding women and children below six years of age. Do not consume alcohol with Repace 25 Tablet as it may increase the risk of low blood pressure. 

Uses of Repace 25 Tablet

Treatment of High blood pressure (hypertension), diabetic nephropathy, and prevention of heart failure/stroke.

Directions for Use

Repace 25 Tablet should be swallowed as a whole with water; do not crush or chew it.

Medicinal Benefits

Repace 25 Tablet belongs to a class of drugs known as angiotensin II receptor blockers used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). Repace 25 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

How Repace 25 Tablet Works

Repace 25 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Repace 25 Tablet

  • Dizziness
  • Tiredness
  • Low blood pressure
  • Weakness
  • Anaemia (lack of blood)
  • Hyperkalaemia (high potassium levels in the blood)
  • Changes in kidney function
  • Orthostatic hypotension (low blood pressure when standing up from lying or sitting position)
  • Hypoglycaemia (low blood sugar)

What if I have taken an overdose of Repace 25 Tablet

Do not take more than the prescribed dose of Repace 25 Tablet as it may cause overdose. The symptoms of overdose include dizziness, fainting, fast or slow heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you have diabetes, kidney or liver problems, please inform your doctor before taking Repace 25 Tablet . Repace 25 Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause serious harm to the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Repace 25 Tablet . Do not consume alcohol with Repace 25 Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Repace 25 Tablet as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking Repace 25 Tablet .

Drug-Drug Interactions

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LosartanQuinapril
Severe
LosartanPotassium chloride
Severe

Drug-Drug Interactions

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LosartanQuinapril
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanPotassium chloride
Severe
How does the drug interact with Repace 25 Tablet:
Co-administration of Repace 25 Tablet with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
LosartanPotassium citrate
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
LosartanEnalapril
Severe
How does the drug interact with Repace 25 Tablet:
Using enalapril together with Repace 25 Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enalapril with Repace 25 Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
LosartanCaptopril
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanPerindopril
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanTrimethoprim
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Repace 25 Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanRamipril
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of ramipril together with Repace 25 Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Repace 25 Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanTizanidine
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.

How to manage the interaction:
Taking Repace 25 Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
LosartanSpironolactone
Severe
How does the drug interact with Repace 25 Tablet:
Coadministration of Repace 25 Tablet with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Repace 25 Tablet with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Repace 25 Tablet Substitute

Substitutes safety advice
  • Aquris Lostan 25 Tablet 10's

    by Others

    2.70per tablet
  • Cosart-25 Tablet 10's

    by Others

    3.65per tablet
  • Losar-25 Tablet 15's

    by Others

    6.03per tablet
  • Covance 25 Tablet 10's

    by Others

    4.82per tablet
  • Losacar 25 Tablet 15's

    by Others

    5.52per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Repace 25 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

When Repace 25 Tablet is used in the pregnancy during the 2nd and 3rd trimesters it affects the renin-angiotensin system can cause injury and even death to the unborn baby. So when pregnancy is detected, Repace 25 Tablet should be discontinued as soon as possible.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Repace 25 Tablet as it may be unsafe for the baby.

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Driving

Caution

Repace 25 Tablet may cause dizziness or drowsiness in some people. So, drive only if you are alert after taking Repace 25 Tablet .

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Liver

Caution

Repace 25 Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Repace 25 Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

It is not recommended for children below 6 years. However, for children above 6 years, give Repace 25 Tablet in doses as prescribed by a doctor.

FAQs

Repace 25 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart).

Repace 25 Tablet works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

No, Repace 25 Tablet is not recommended for use during pregnancy especially in the second and third trimesters as it may harm the developing baby. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking Repace 25 Tablet .

You are not recommended to take more than the prescribed dose of Repace 25 Tablet as it may cause Repace 25 Tablet overdose resulting in symptoms such as low blood pressure, fast or slow heartbeat. However, if you experience any of these symptoms while taking Repace 25 Tablet , please consult a doctor immediately.

No, you are not recommended to take ibuprofen with Repace 25 Tablet as co-administration of these two medicines may reduce the effect of Repace 25 Tablet and increase the risk of impaired kidney function. However, if you experience loss of appetite, sudden weight loss or weight gain, weakness, muscle cramps, vomiting, nausea, decreased or increased urination, irregular heart rhythm and fluid retention, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REP0002

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