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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST

Reopro 10 mg Injection 5 ml is used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Reopro 10 mg Injection 5 ml contains Abciximab, which works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

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Prescription drug

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Composition

ABCIXIMAB-10MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Reopro 10 mg Injection 5 ml

Reopro 10 mg Injection 5 ml belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Reopro 10 mg Injection 5 ml is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

Reopro 10 mg Injection 5 ml may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Reopro 10 mg Injection 5 ml should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Reopro 10 mg Injection 5 ml

Treatment of Myocardial infarction (heart attack)

Medicinal Benefits

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

Directions for Use

A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Reopro 10 mg Injection 5 ml

  • Bleeding
  • Nausea
  • Headache
  • Abdominal pain
  • Hypotension
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection

Drug Warnings

Do not receive Reopro 10 mg Injection 5 ml if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug Interactions

Drug-Drug Interactions: Reopro 10 mg Injection 5 ml may interact with pain killers (aspirin, ibuprofen, celecoxib, hydrocodone, tramadol), blood thinners (clopidogrel, dalteparin, enoxaparin, rivaroxaban, prasugrel), ACE Inhibitors (captopril, Enalapril), calcium channel blockers (nifedipine, cilnidipine), beta-blockers (atenolol, sotalol), warfarin, heparin.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have bleeding problems, coronary and cerebral vascular disease, liver or kidney disease.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • CLOPIDOGREL
  • ENOXAPARIN
  • CAPTOPRIL
  • ENALAPRIL
  • NIFEDIPINE
  • CILNIDIPINE
  • ATENOLOL
  • SOTALOL
  • WARFARIN
  • HEPARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Special Advise

  • Before administration of Reopro 10 mg Injection 5 ml, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
  • As Reopro 10 mg Injection 5 ml will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.

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Pregnancy

Caution

It is also unknown whether Reopro 10 mg Injection 5 ml can cause fetal damage or alter reproductive capacity when given to a pregnant woman. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Caution

Limited data are available on the effect of Reopro 10 mg Injection 5 ml on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Reopro 10 mg Injection 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Reopro 10 mg Injection 5 ml is used in PCI procedures in a hospital setting. Driving is not recommended.

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Liver

Caution

If you have liver problems, inform your doctor beforehand.

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Kidney

Unsafe

If you have kidney impairment, inform your doctor beforehand.

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Children

Unsafe

Reopro 10 mg Injection 5 ml is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, Haryana, India
Other Info - REO0004

FAQs

Reopro 10 mg Injection 5 ml is used to treat Myocardial infarction (heart attack).
Reopro 10 mg Injection 5 ml contains Abciximab, which works by blocking the activity of glycoprotein IIb/IIIa receptor and thereby prevents platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.
Reopro 10 mg Injection 5 ml is usually administered along with heparin and aspirin, so it might increase the risk of bleeding. Inform the doctor immediately if you notice excess bleeding.
Reopro 10 mg Injection 5 ml may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.
While taking Reopro 10 mg Injection 5 ml, avoid medicines like painkillers (aspirin, ibuprofen, celecoxib, hydrocodone, tramadol), blood thinners (clopidogrel, dalteparin, enoxaparin, rivaroxaban, prasugrel, warfarin, heparin), ACE inhibitors (captopril, enalapril), calcium channel blockers (nifedipine, cilnidipine), and beta-blockers (atenolol, sotalol) due to potential interactions. Therefore, always consult your doctor before using Reopro 10 mg Injection 5 ml with other medicines.
You may begin to feel better within a few hours to a day after receiving Reopro 10 mg Injection 5 ml, as it acts quickly to prevent blood clots. However, complete improvement could take a couple of days, based on your condition. If you have any concerns regarding this, please discuss with your doctor.
Reopro 10 mg Injection 5 ml causes side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. However, contact a doctor if these side effect persists longer.

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Keep Refrigerated. Do not freeze.Prepaid payment required.