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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Renphron 10000 IU Injection 1 ml is used to treat anaemia due to chronic kidney disease and chemotherapy. It contains Erythropoietin alfa, human recombinant which works by stimulating the bone marrow to make more red blood cells. This medicine may sometimes cause side effects such as high blood pressure, nausea, vomiting and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Plasoron Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Renphron 10000 IU Injection 1 ml

Renphron 10000 IU Injection 1 ml belongs to a class of drugs known as erythropoiesis-stimulating agent (ESA) primarily used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and anaemia due to chemotherapy (cancer treatment). Anaemia is reduced levels of haemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anaemia, which gets worse as the disease progresses. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anaemia in cancer patients.

Renphron 10000 IU Injection 1 ml contains ‘Erythropoietin alfa, human recombinant’. Renphron 10000 IU Injection 1 ml works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Renphron 10000 IU Injection 1 ml is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

Renphron 10000 IU Injection 1 ml will be administered by a healthcare professional; do not self-administer. You may experience high blood pressure, nausea, vomiting and fever. Most of these side effects of Renphron 10000 IU Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Renphron 10000 IU Injection 1 ml or any other medicines, please tell your doctor. Renphron 10000 IU Injection 1 ml should not be taken in conditions like heart disease, high blood pressure, or liver disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Renphron 10000 IU Injection 1 ml. Renphron 10000 IU Injection 1 ml may affect your ability to drive and use machines as Renphron 10000 IU Injection 1 ml may cause fits disorder during the first 90 days of treatment. 

Uses of Renphron 10000 IU Injection 1 ml

Treatment of Anemia due to chronic kidney disease, Anemia due to chemotherapy.

Directions for Use

Renphron 10000 IU Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Renphron 10000 IU Injection 1 ml helps in the treatment of anemia which may happen due to chronic kidney disease and cancer chemotherapy. Renphron 10000 IU Injection 1 ml works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Renphron 10000 IU Injection 1 ml is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood). Besides this Renphron 10000 IU Injection 1 ml is also used for the treatment of anemia caused by a medicine known as zidovudine for the treatment of HIV (human immunodeficiency viruses). Renphron 10000 IU Injection 1 ml also decreases the requirement for blood cell transfusions.

How Renphron 10000 IU Injection 1 ml Works

Renphron 10000 IU Injection 1 ml contains ‘Erythropoietin alfa, human recombinant’. Renphron 10000 IU Injection 1 ml works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Renphron 10000 IU Injection 1 ml is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Renphron 10000 IU Injection 1 ml

  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Joint pain
  • Clotting at the injection site

What if I have taken an overdose of Renphron 10000 IU Injection 1 ml

Since Renphron 10000 IU Injection 1 ml is administered by a healthcare professional, an overdose is unlikely to occur. Signs and symptoms of overdose may include excessive and/or rapid increase in haemoglobin concentration and cardiovascular events. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to Renphron 10000 IU Injection 1 ml or any other medicines, please tell your doctor. Renphron 10000 IU Injection 1 ml should not be taken in conditions like high blood pressure, heart disease, heart attack, blood clot in the brain (stroke), fits disorder, liver disease, or kidney disease. Before taking Renphron 10000 IU Injection 1 ml inform your doctor if you have any type of cancer or skin reactions. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Renphron 10000 IU Injection 1 ml. Renphron 10000 IU Injection 1 ml may affect your ability to drive and using machines as Renphron 10000 IU Injection 1 ml may cause fits to disorder during the first 90 days of treatment. Renphron 10000 IU Injection 1 ml should not be used for children below 1 month of age during treatment of anemia due to chronic kidney disease. Renphron 10000 IU Injection 1 ml should not be used for children below 5 years of age during treatment of anemia due to chemotherapy.

Drug-Drug Interactions

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ErythropoietinCarfilzomib
Severe
ErythropoietinThalidomide
Severe

Drug-Drug Interactions

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ErythropoietinCarfilzomib
Severe
How does the drug interact with Renphron 10000 IU Injection 1 ml:
Carfilzomib can cause serious blood clots and taking it alongside Renphron 10000 IU Injection 1 ml may enhance the risk.

How to manage the interaction:
Co-administration of Renphron 10000 IU Injection 1 ml with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinThalidomide
Severe
How does the drug interact with Renphron 10000 IU Injection 1 ml:
Taking thalidomide with Renphron 10000 IU Injection 1 ml may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Renphron 10000 IU Injection 1 ml and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ErythropoietinLenalidomide
Severe
How does the drug interact with Renphron 10000 IU Injection 1 ml:
Combining Renphron 10000 IU Injection 1 ml with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Renphron 10000 IU Injection 1 ml and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Renphron 10000 IU Injection 1 ml:
Pomalidomide can cause serious blood clots and taking it alongside Renphron 10000 IU Injection 1 ml may enhance the risk.

How to manage the interaction:
Co-administration of Renphron 10000 IU Injection 1 ml with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Your doctor may get your blood tests done frequently to examine the levels of blood cells, hemoglobin, and electrolytes such as potassium in your blood.
  • Eat food that is rich in iron, vitamin B12, and folic acid.
  • Eat food like leafy, green vegetables, fish, eggs, and liver.
  • Do mild to moderate exercise.

Habit Forming

No

Therapeutic Class

ERYTHROPOIESIS STIMULATING AGENTS (ESAs)

Renphron 10000 IU Injection 1 ml Substitute

Substitutes safety advice
  • Erynex 10000 Injection 1's

    2205.00per tablet
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Alcohol

Caution

It is not known that Renphron 10000 IU Injection 1 ml may interact with alcohol. Therefore, avoid drinking alcohol while using Renphron 10000 IU Injection 1 ml.

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Pregnancy

Caution

Renphron 10000 IU Injection 1 ml should not be taken until prescribed. Your doctor will decide what is the best treatment for you. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking Renphron 10000 IU Injection 1 ml. Your doctor will advise you to either stop or continue treatment.

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Driving

Caution

Renphron 10000 IU Injection 1 ml may affect your ability to drive and using machines as Renphron 10000 IU Injection 1 ml may cause fits to disorder during the first 90 days of treatment.

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Liver

Caution

Take Renphron 10000 IU Injection 1 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Renphron 10000 IU Injection 1 ml is safely given to the kidney patients only if prescribed by your doctor.

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Children

Caution

Renphron 10000 IU Injection 1 ml should be used in children only when prescribed by a doctor.

FAQs

Renphron 10000 IU Injection 1 ml is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and chemotherapy (cancer treatment).
Yes, Renphron 10000 IU Injection 1 ml can be used for children above 1 month of age during treatment of anemia due to chronic kidney disease. Renphron 10000 IU Injection 1 ml can be used for children above 5 years of age during treatment of anemia due to chemotherapy. The effectiveness of Renphron 10000 IU Injection 1 ml and side effects observed in children is the same as adults, and used only when prescribed by a doctor.
Yes, Renphron 10000 IU Injection 1 ml may increase the blood pressure. During initial treatment with Renphron 10000 IU Injection 1 ml, blood pressure should be examined and those who have high blood pressure should take proper methods to regulate blood pressure. Your doctor may stop Renphron 10000 IU Injection 1 ml if the blood pressure continues uncontrolled.
Renphron 10000 IU Injection 1 ml works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This Renphron 10000 IU Injection 1 ml is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood).
The most common side effects of Renphron 10000 IU Injection 1 ml are high blood pressure, nausea, vomiting, and fever, diarrhea, feeling upset in the stomach, skin rashes, stuffy nose, sore throat, bone, or muscle pain. Most of these side effects of Renphron 10000 IU Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Shop No 5 First Floor Dda(Csc) Market, Gtb Enclav Pocket - F, Nand Nagari Delhi -110093
Other Info - REN0189

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