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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Renophylline 25 mg Injection is used to treat Asthma and Chronic obstructive pulmonary disease (COPD). It contains Aminophylline, which relaxes and opens air passages in the lungs, making breathing easier. Besides this, it relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes. Common side effects of Renophylline 25 mg Injection are upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability.

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Composition :

AMINOPHYLLINE-25MG

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Renophylline 25 mg Injection

Renophylline 25 mg Injection belongs to the class of drugs called bronchodilators. It is indicated for the relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Renophylline 25 mg Injection contains Aminophylline, which helps to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, making breathing easier.

Renophylline 25 mg Injection is usually administered by a qualified healthcare professional; do not self-administer. Renophylline 25 mg Injection may cause certain side effects, including upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability. Most of these side effects of Renophylline 25 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before prescribing the Renophylline 25 mg Injection, let your doctor know about all your medical conditions, allergic reactions, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Renophylline 25 mg Injection may cause insomnia and restlessness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Uses of Renophylline 25 mg Injection

Treatment of Asthma and Chronic obstructive pulmonary disease (COPD)

Directions for Use

Renophylline 25 mg Injection will be administered by a trained healthcare professional. Do not self-administer.

Medicinal Benefits

Renophylline 25 mg Injection contains Aminophylline. It belongs to the class of drugs called bronchodilators. It is indicated to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease. Aminophylline relaxes and opens air passages in the lungs, making breathing easier. It also relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes.

How Renophylline 25 mg Injection Works

Renophylline 25 mg Injection contains Aminophylline, which helps to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, making breathing easier.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Renophylline 25 mg Injection

  • Upset stomach
  • Stomach pain
  • Diarrhea
  • Headache
  • Restlessness
  • Insomnia
  • Irritability
  • Injection site reaction

What if I have taken an overdose of Renophylline 25 mg Injection

Since Renophylline 25 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Renophylline 25 mg Injection may cause vomiting, hypokalemia, hyperglycemia, sinus tachycardia, seizures, and arrhythmias.

Drug Warnings

Before receiving Renophylline 25 mg Injection, let your doctor know about all your medical conditions, such as if you have or have ever had seizures, heart disease, an overactive or underactive thyroid gland, high blood pressure, or kidney or liver disease or if you have a history of alcohol abuse, allergic reactions (especially aminophylline, theophylline’s, theobromine, caffeine or to any of the excipients present in Renophylline 25 mg Injection), and all medication history you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before receiving Renophylline 25 mg Injection. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
AminophyllinePindolol
Severe

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Riociguat may significantly lower your blood pressure.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Riociguat can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllinePindolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Pindolol together can make pindolol less effective and increase the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Pindolol may lead to an interaction, it can be taken only if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineCiprofloxacin
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Ciprofloxacin together could increase the levels and enhance the effects of Renophylline 25 mg Injection 10 ml. Increased levels of Renophylline 25 mg Injection 10 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Ciprofloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineSotalol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Using sotalol together with Renophylline 25 mg Injection 10 ml can make sotalol less effective and increase the risk or severity of Renophylline 25 mg Injection 10 ml side effects.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Sotalol can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineAtenolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of atenolol with Renophylline 25 mg Injection 10 ml could certainly reduce the efficacy of atenolol and enhance the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking atenolol alongside Renophylline 25 mg Injection 10 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineDeferasirox
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Combining Renophylline 25 mg Injection 10 ml with Deferasirox may significantly increase the blood levels of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Deferasirox can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, headache, confusion, restlessness, sleeplessness, fits, heart palpitations, or irregular heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineLabetalol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Combination of Renophylline 25 mg Injection 10 ml with Labetalol can make labetalol less effective and increase the side effects of Renophylline 25 mg Injection 10 ml which can be serious.

How to manage the interaction:
Although taking Labetalol and Renophylline 25 mg Injection 10 ml together can result in an interaction, it can be taken only if a doctor has advised it. However, if you experience irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetoprolol Tartrate
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Co-administration of Renophylline 25 mg Injection 10 ml with Metoprolol could increase the effects of Renophylline 25 mg Injection 10 ml and decrease the effects of Metoprolol.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Metoprolol can cause an interaction, it can be taken only if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineTramadol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Tramadol with Renophylline 25 mg Injection 10 ml can increase the risk of cause seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml and tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as seizures, dizziness, drowsiness, or difficulty concentrating, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
AminophyllineMetoprolol Succinate
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Co-administration of Renophylline 25 mg Injection 10 ml with Metoprolol could reduce the effects of Metoprolol and increase the affects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Metoprolol can cause an interaction; however, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet, especially green leafy vegetables, and strictly do not consume alcohol or caffeine (coffee, tea, cola drinks, and chocolate).
  • Drink plenty of fluids daily to thin mucus, making it easier to cough out.
  • Smoking should be avoided while receiving Renophylline 25 mg Injection as it can alter the blood levels of aminophylline, which may affect the dosing.
  • It is very important to maintain hygiene, like washing hands after coming from outside, as people with asthma or COPD are at a greater risk of infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

Renophylline 25 mg Injection Substitute

Substitutes safety advice
  • Aminolin Injection 10 ml

    3.24per tablet
  • Aminarc 25mg Injection

    3.60per tablet
  • Pharmacure Aminophylline Injection 10 ml

    7.50per tablet
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Alcohol

Caution

Alcohol may increase the levels of aminophylline in the blood, leading to serious side effects. Discuss with your doctor if you have concerns.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Renophylline 25 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Small amounts of aminophylline are excreted in human milk. Hence, if you are breastfeeding, inform your doctor before receiving Renophylline 25 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Renophylline 25 mg Injection has no or negligible influence on the ability to drive.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Renophylline 25 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Renophylline 25 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kidney disease in an infant less than three months of age may affect the functioning of Renophylline 25 mg Injection.

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Children

Caution

Caution should be maintained while using Renophylline 25 mg Injection in infants less than three months and with kidney disease. Please consult your doctor. Your doctor may prescribe this medicine for your child if the benefits outweigh the risks.

FAQs

Renophylline 25 mg Injection is used to treat Asthma and Chronic obstructive pulmonary disease (COPD).
Renophylline 25 mg Injection contains Aminophylline, a bronchodilator that relaxes and widens the muscles of the airways, thereby making it easier for asthma and COPD patients to breathe.
Avoid aerated drinks, fried foods, excess salts (sodium chloride or table salt), dairy products, cruciferous veggies, cold cuts, and cured meats. Also, avoid consuming high amounts of caffeine-containing tea, coffee, chocolate, and cola, as these foods already contain aminophylline, an active constituent of Renophylline 25 mg Injection. Sulfites in alcoholic beverages can trigger symptoms of asthma and COPD, so avoid consuming alcoholic beverages.
No, you are not recommended to smoke while receiving Renophylline 25 mg Injection as it may reduce the effectiveness of Renophylline 25 mg Injection and damage your lung's airways (alveoli). Long-term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.
Renophylline 25 mg Injection should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Renophylline 25 mg Injection so that the dose may be adjusted or an alternate medicine may be prescribed.
No, Renophylline 25 mg Injection does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
You are not recommended to take Renophylline 25 mg Injection with antibiotics such as erythromycin, tetracycline, amoxicillin, amikacin and gentamicin at the same time as it may reduce the effectiveness of antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of a minimum of 2 hours between taking Renophylline 25 mg Injection and antibiotics. However, please consult a doctor before using Renophylline 25 mg Injection with antibiotics or other medicines.

Country of origin

India

Manufacturer/Marketer address

Industrial Area Patna 800013
Other Info - REN0065

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