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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:48 PM IST

Refzil O 250 Tablet is used to treat bacterial infections. It contains Cefprozil which works by inhibiting the growth of bacteria. In some cases, this medicine may cause side effects such as stomach pain, dizziness, diarrhoea, nausea, and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition

CEFPROZIL-250MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Refzil O 250 Tablet

Refzil O 250 Tablet belongs to a class of medications called ‘Antibiotics’ used to treat bacterial infections. It is used in the treatment of various bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection) and skin infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Refzil O 250 Tablet does not work against infections caused by the virus, including cold and flu.

Refzil O 250 Tablet contains ‘Cefprozil’, which is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Thus, it helps in treating and preventing the spread of infections.

It would be best if you took Refzil O 250 Tablet as prescribed by your doctor. The common side-effects of Refzil O 250 Tablet are nausea, diarrhoea, and vaginal itching or discharge. It may also cause abnormal liver function tests and decreased blood cell (WBC) count. These side effects usually don't require medical attention. Inform your doctor immediately if any of these side effects persist or get worse.

It is not recommended to take Refzil O 250 Tablet if you are allergic to any antibiotics, including penicillin and cephalosporin antibiotics. Before taking Refzil O 250 Tablet , inform your doctor if you have intestinal problems such as colitis (inflammation of the intestine) and kidney diseases. Do not take Refzil O 250 Tablet on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Refzil O 250 Tablet is probably safe when used in pregnant and breastfeeding women. Refzil O 250 Tablet should be used with caution in children and the elderly as dosage adjustments are necessary.  Refzil O 250 Tablet may not interact with alcohol. Refzil O 250 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Refzil O 250 Tablet

Refzil O 250 Tablet is used to treat Bacterial infections

Medicinal Benefits

Refzil O 250 Tablet contains ‘Cefprozil’, which is a cephalosporin antibiotic. It acts by disrupting the formation of the cell wall (outer layer), which is essential for bacteria's survival, thereby killing the bacteria. It is a broad-spectrum antibiotic and acts against both gram-positive and gram-negative bacteria. It can effectively treat bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection), and skin infections.

Directions for Use

This medicine is available in the form of tablets and suspension. Tablets: You should swallowRefzil O 250 Tablet with a glass of water. Do not crush, chew, or break it. It can be taken with or without food. However, you can take it after meals if you have an upset stomach. The dose and duration are prescribed by the doctor based on your health condition.Suspension: For suspensions, Refzil O 250 Tablet is available as a dry powder in a bottle. A liquid is provided to make a suspension. If the liquid is not available, you may also use boiled and cooled water. There will be a mark on the bottle to determine the water to be added. If the mark is absent, you may ask your pharmacist or refer to the patient information leaflet (PIL) about the amount of water to be added. A measuring cup is used to measure the required amount of water and poured into the dry powder. Shake the bottle well before each use. Store the remaining suspension for the next use in the refrigerator. Do not freeze the medicine. Discard any unused medicine older than 2 weeks after opening the bottle.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Refzil O 250 Tablet

  • Nausea
  • Diarrhoea
  • Vaginal itching or discharge
  • Abnormal liver function tests
  • Low white blood cell (WBC) count

Drug Warnings

Refzil O 250 Tablet should be used with caution in patients with kidney diseases. Do not take Refzil O 250 Tablet on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. You may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ after using Refzil O 250 Tablet . So, please undergo an examination to rule out CDAD's chances if you experience diarrhoea following the use of Refzil O 250 Tablet . Do not use it for prolonged periods than recommended by your doctor. Long-term use can lead to superinfection (additional infection caused by other microbes).

Drug Interactions

Drug-Drug Interactions: Refzil O 250 Tablet may interact with other cephalosporin antibiotics, aminoglycoside antibiotics (amikacin, gentamicin, kanamycin, and streptomycin), and medicine used to treat gout or high uric acid levels (probenecid).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Refzil O 250 Tablet should be used with caution in patients with kidney diseases and intestinal problems such as colitis (colon inflammation).

Drug-Drug Interactions Checker List

  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • PROBENECID

Habit Forming

No

Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Refzil O 250 Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet. Fibre-rich foods can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid alcoholic beverages with Refzil O 250 Tablet as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Refzil O 250 Tablet in fighting off infections.

Special Advise

  • Refzil O 250 Tablet may cause live bacterial vaccines (such as typhoid vaccine) to be ineffective. Do not have any immunization/vaccinations while using this medication unless your doctor tells you to.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms like fever, chills and fatigue.  A few harmful bacteria commonly cause infections, including Streptococcus, Staphylococcus and E. coli.  Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.

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Alcohol

Caution

Avoid consuming alcohol along with Refzil O 250 Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant before taking Refzil O 250 Tablet . Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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Breast Feeding

Safe if prescribed

Refzil O 250 Tablet is probably safe when used in breastfeeding. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing.

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Driving

Caution

Refzil O 250 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after taking this medicine.

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Liver

Safe if prescribed

Refzil O 250 Tablet is probably safe when used in patients with liver diseases. However, please consult your doctor before taking this medicine.

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Kidney

Caution

Refzil O 250 Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose based on your condition.

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Children

Caution

Use Refzil O 250 Tablet in children in prescribed doses. The dose will be determined by your doctor based on your child's condition, age and body weight.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REF0008

Author Details

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FAQs

Refzil O 250 Tablet is used to treat bacterial infections such as pharyngitis (sore throat), tonsillitis (swollen tonsils), otitis media (middle ear infection), sinusitis (sinus infection), bronchitis (inflammation of the bronchi or lower respiratory tract infection) and skin infections.
Refzil O 250 Tablet contains ‘Cefprozil’, that is used to treat bacterial infections. It reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival.
Refzil O 250 Tablet may disrupt the natural flora present in the gut leading to ‘Clostridium difficile-associated diarrhoea'. Drink lots of fluids to avoid dehydration if you experience diarrhoea. Take probiotics to restore the gut bacteria after completing the course of antibiotics. Consult a doctor if you have watery or bloody stools.
People allergic to penicillin should not take Refzil O 250 Tablet as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Refzil O 250 Tablet contains cefprozil, which has a similar structure to that of penicillin.
Refzil O 250 Tablet does not treat a viral infection like the flu or a common cold. So if you feel under the weather, it is best to consult the doctor to know if you need Refzil O 250 Tablet for your condition.
The common side-effects of Refzil O 250 Tablet are nausea, diarrhoea, and vaginal itching or discharge. It may also cause abnormal liver function tests and decreased white blood cell (WBC) count. These side effects usually don't require medical attention. However, inform your doctor immediately if any of these side effects persist or get worse.
Use of Refzil O 250 Tablet for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.
Yes, Refzil O 250 Tablet is safe if taken in the dose and duration prescribed by the doctor.
Yes, Refzil O 250 Tablet is a cephalosporin antibiotic used to treat bacterial infections.
Do not discontinue Refzil O 250 Tablet without consulting your doctor. To treat your condition effectively, keep taking Refzil O 250 Tablet for the prescribed duration.
Refzil O 250 Tablet starts working as soon as you start taking the medicine. However, it might take a few days to treat the infection completely. Therefore, finish the course of treatment as advised by the doctor.
Consult the doctor if you do not feel better after using Refzil O 250 Tablet or if your condition worsens during treatment. The doctor may adjust the dose or prescribe alternate medicine.

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