apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 13, 2024 | 11:26 AM IST
Reflin 1gm Injection is used to treat bacterial infections. It contains Cefazolin which works by interfering with the formation of bacterial cell walls, thereby killing the bacteria. In some cases, this medicine may cause side effects such as injection site reactions (pain, swelling, redness), vomiting, nausea, indigestion, diarrhoea, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

CEFAZOLIN-1GM

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Reflin 1gm Injection

Reflin 1gm Injection belongs to the group of antibiotics called 'cephalosporin' used to treat various bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, Reflin 1gm Injection also used before surgeries to prevent post-surgical bacterial infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Reflin 1gm Injection does not work against infections caused by the virus, including cold and flu.

Reflin 1gm Injection contains 'Cefazolin' works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This allows holes to appear in the bacterial cell walls, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.

You are advised to take Reflin 1gm Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Reflin 1gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Some patients may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ a condition in which healthy bacteria in the colon (intestine) are disrupted.

If you are allergic to Reflin 1gm Injection, penicillins or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Reflin 1gm Injection. Drive only if you are alert as Reflin 1gm Injection may cause dizziness. You are recommended to complete the full course of Reflin 1gm Injection as prescribed by your doctor for effective results. Please do not take Reflin 1gm Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. 

Uses of Reflin 1gm Injection

Treatment of Bacterial infections

Medicinal Benefits

Reflin 1gm Injection belongs to the group of antibiotic medicines called cephalosporins used to treat various bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).  It is also used before surgeries to prevent post-surgical bacterial infections. Reflin 1gm Injection contains Cefazolin is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria.  Reflin 1gm Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

Directions for Use

It will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Reflin 1gm Injection

  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Allergic reaction
  • Indigestion
  • Diarrhoea
  • Lightheadedness
  • Dizziness

Drug Warnings

If you are allergic to Reflin 1gm Injection, penicillins or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhoea, haemolytic anaemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, inflammation of the large intestine, inform your doctor before taking Reflin 1gm Injection. Do not take Reflin 1gm Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Do not take antacids and calcium-containing products along with Reflin 1gm Injection; maintain a gap of 2-3 hours between both. If you are pregnant or breastfeeding, please inform your doctor before taking Reflin 1gm Injection. Use Reflin 1gm Injection with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. You are recommended to complete the full course of Reflin 1gm Injection as prescribed by your doctor for effective results. Drive only if you are alert as Reflin 1gm Injection may cause dizziness. Avoid alcohol consumption while taking Reflin 1gm Injection to prevent unpleasant side-effects. Inform your doctor about all the medicines you are taking and about your health condition to rule out any undesirable side-effects. 

Drug Interactions

Drug-Drug Interaction: Reflin 1gm Injection may interact with a blood thinner (warfarin, heparin), drugs used to lower high uric acid levels (probenecid), water pills or diuretics (furosemide, bumetanide), antibiotics (chloramphenicol, gentamicin, streptomycin, neomycin, tobramycin), vaccine (BCG, cholera, typhoid).

Drug-Food Interaction: Reflin 1gm Injection may interact with alcohol. Therefore, avoid the consumption of alcohol with Reflin 1gm Injection as it may increase the risk of adverse effects.

Drug-Disease Interaction: If you have kidney or liver problems, diarrhoea, haemolytic anaemia (reduction in red blood cells that may cause breathlessness or weakness and make your skin pale yellow), kidney or gall stones, inflammation of the large intestine and liver disease, inform your doctor before taking Reflin 1gm Injection.

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • PROBENECID
  • FUROSEMIDE
  • BUMETANIDE
  • CHLORAMPHENICOL
  • GENTAMICIN
  • NEOMYCIN
  • TOBRAMYCIN
  • STREPTOMYCIN
  • BACILLUS CALMETTE-GUERIN(BCG) VACCINE
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Reflin 1gm Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Reflin 1gm Injection.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and tobacco to treat your condition effectively.
  • To cure your condition effectually complete the full course of Reflin 1gm Injection even though you find symptomatic relief.

Special Advise

  • Reflin 1gm Injection must not be mixed or administered simultaneously with calcium-containing solutions, including total parenteral nutrition.
  • Regular blood tests are recommended if you take Reflin 1gm Injection for a long time to monitor changes in white blood cells, platelets and liver functioning.
  • If you are about to undergo any blood or urine tests, inform your doctor that you are taking Reflin 1gm Injection as it may interfere with urine test (for sugar) and Coomb’s test results.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection. 

bannner image

Alcohol

Unsafe

Avoid consuming alcohol while taking Reflin 1gm Injection to prevent unpleasant side-effects.

bannner image

Pregnancy

Caution

Reflin 1gm Injection is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

bannner image

Breast Feeding

Caution

Reflin 1gm Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

bannner image

Driving

Caution

Reflin 1gm Injection may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Reflin 1gm Injection.

bannner image

Liver

Caution

Take Reflin 1gm Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Reflin 1gm Injection should be used in patients with kidney diseases with extreme caution as Reflin 1gm Injection may cause renal toxicity. Dose adjustments are necessary.

bannner image

Children

Safe if prescribed

Reflin 1gm Injection is safe for children if prescribed by a doctor. Do not use Reflin 1gm Injection in a child without a doctor's advice. Reflin 1gm Injection should never be used in a premature baby, or in any new-born baby who has jaundice (yellowing of the skin or eyes).

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REF0001

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Reflin 1gm Injection is used to treat bacterial infections of the nose, lungs, ear, bones, joints, skin, urinary tract, prostate gland and reproductive system. Besides this, it is also used before surgeries to prevent post-surgical bacterial infections.
Reflin 1gm Injection contains Cefazolin which works by interfering with the formation of bacterial cell walls, thereby impairing the bonds that hold the bacterial cell wall together. This process ultimately disrupts the formation of bacterial cell wall formation, which kills the bacteria. Thus, it helps in treating and preventing the spread of infections.
Diarrhoea might be a side-effect of Reflin 1gm Injection. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Reflin 1gm Injection even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Reflin 1gm Injection may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Reflin 1gm Injection.
Reflin 1gm Injection should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Reflin 1gm Injection so that the dose may be adjusted accordingly.
Consult the doctor if you think Reflin 1gm Injection isn’t working for you. Your doctor may increase the dose or prescribe alternate medication based on your condition.
Consult the doctor if your condition does not get better even after completing the duration of treatment or if your condition worsens during treatment with Reflin 1gm Injection.
In some cases, Reflin 1gm Injection may cause side effects like injection site reactions (pain, swelling, redness), vomiting, allergic reaction, nausea, indigestion, diarrhoea, lightheadedness and dizziness. Most of these side effects of Reflin 1gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.