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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Jan 1, 2025 | 2:49 PM IST
RCINEX R CIN + INH 450MG CAPSULE is used to treat and prevent tuberculosis. It contains Rifampicin, and Isoniazid, which works by killing the bacteria causing TB (tuberculosis). In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Uses of RCINEX R CIN + INH 450MG CAPSULE

Treatment of Tuberculosis.

Medicinal Benefits

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

Side Effects of RCINEX R CIN + INH 450MG CAPSULE

  • Drowsiness
  • Dizziness
  • Headache
  • Weakness
  • Muscle pain 
  • Heartburn 
  • Diarrhoea
  • Gas
  • Numbness 

Directions for Use

Take RCINEX R CIN + INH 450MG CAPSULE 30 minutes before food or 2 hours after food. Swallow RCINEX R CIN + INH 450MG CAPSULE as a whole; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take RCINEX R CIN + INH 450MG CAPSULE if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting RCINEX R CIN + INH 450MG CAPSULE, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Drug Interactions

verifiedApollotooltip
RifampicinIndinavir
Critical
RifampicinDarunavir
Critical

Drug-Food Interactions

verifiedApollotooltip
RIFAMPICIN-450MG+ISONIAZID-300MGTyramine-containing food
Moderate

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

  • Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system. 

  • Avoid processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from cough.

  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.

  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

How RCINEX R CIN + INH 450MG CAPSULE Works

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

What if I have taken an overdose of RCINEX R CIN + INH 450MG CAPSULE

Do not take more than the prescribed dose of RCINEX R CIN + INH 450MG CAPSULE as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, headache, itching, tiredness, dizziness, lightheadedness, drowsiness, fainting, blurred vision, or hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe RCINEX R CIN + INH 450MG CAPSULE only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

RCINEX R CIN + INH 450MG CAPSULE passes into breast milk. Do not breastfeed while taking RCINEX R CIN + INH 450MG CAPSULE.

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Driving

Caution

RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RCINEX R CIN + INH 450MG CAPSULE.

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Children

Consult your doctor

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0006

Author Details

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RCINEX R CIN + INH 450MG CAPSULE Substitute

Substitutes safety advice
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FAQs

RCINEX R CIN + INH 450MG CAPSULE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis.
RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking RCINEX R CIN + INH 450MG CAPSULE despite symptomatic relief. To treat your condition effectually, continue taking RCINEX R CIN + INH 450MG CAPSULE for as long as it has been prescribed for you.
Do not take RCINEX R CIN + INH 450MG CAPSULE along with antacids as it might decrease the effectiveness of RCINEX R CIN + INH 450MG CAPSULE. Maintain a minimum gap of 1hour between both.
Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from RCINEX R CIN + INH 450MG CAPSULE.
RCINEX R CIN + INH 450MG CAPSULE contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking RCINEX R CIN + INH 450MG CAPSULE.
RCINEX R CIN + INH 450MG CAPSULE might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking RCINEX R CIN + INH 450MG CAPSULE. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.
RCINEX R CIN + INH 450MG CAPSULE may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking RCINEX R CIN + INH 450MG CAPSULE. Do not worry as it is a common side-effect of RCINEX R CIN + INH 450MG CAPSULE.
Yes, RCINEX R CIN + INH 450MG CAPSULE might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking RCINEX R CIN + INH 450MG CAPSULE.
RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.
Yes, RCINEX R CIN + INH 450MG CAPSULE may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking RCINEX R CIN + INH 450MG CAPSULE to check how your liver is functioning.
Yes, RCINEX R CIN + INH 450MG CAPSULE can cause temporary discoloration of urine and sweat. This is a common and harmless side effect.
RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, Rifampicin and Isoniazid. It is used in the treatment of Tuberculosis.
Before using RCINEX R CIN + INH 450MG CAPSULE, you should learn about its use, side effects, and limitations.
If you forget a dose of RCINEX R CIN + INH 450MG CAPSULE, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
The best time to take RCINEX R CIN + INH 450MG CAPSULE is 30 minutes before food or 2 hours after food. This helps your body absorb the medication more effectively.
Store RCINEX R CIN + INH 450MG CAPSULE in a cool, dry place out of sunlight and children's reach. Check the expiration date regularly. To dispose of it, place it in a plastic bag and throw it away in household trash. Never flush it down the toilet or sink.
You should avoid alcohol while taking RCINEX R CIN + INH 450MG CAPSULE strictly to ensure safety and efficacy, as it can increase the risk of liver damage when combined with medications like Isoniazid and Rifampicin.
Common side effects of RCINEX R CIN + INH 450MG CAPSULE may include drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
RCINEX R CIN + INH 450MG CAPSULE is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

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