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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
R-Cin Suspension is used in combination with other medicines to treat tuberculosis (TB). It contains Rifampicin, which inhibits the growth of bacteria. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

RIFAMPICIN-100MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About R-Cin Suspension

R-Cin Suspension is used in combination with other medicines to treat tuberculosis (TB). Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It is also used to treat other bacterial infections. R-Cin Suspension does not work against infections caused by the virus, including cold and flu. As R-Cin Suspension is an antibiotic, it does not work against infections caused by the virus, including cold and flu. The bacteria causing tuberculosis (TB) are highly contagious and spread from one person to another via tiny droplets released into the air (through coughs or sneezes).

R-Cin Suspension consists of a drug called 'rifampicin', which works by inactivating a bacterial protein enzyme (RNA-polymerase) and inhibits bacterial cell death.  R-Cin Suspension acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis). 

R-Cin Suspension should be taken as recommended by your doctor. It should be taken 30 minutes before food or 2 hours after food on an empty stomach. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Most of these side effects are mild and subside over time. However, if any of these effects persist, contact your doctor immediately.

R-Cin Suspension may raise liver enzymes like ALT and can cause jaundice if taken longer. Hence, a regular liver function test (LFT) is recommended while taking treatment with R-Cin Suspension . Maintain a gap of one hour between R-Cin Suspension and antacid medicines. R-Cin Suspension is not recommended if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking R-Cin Suspension as it passes into breast milk. R-Cin Suspension may cause dizziness, and vision problems; hence avoid driving vehicles or operating machines that require mental concentration. Avoid alcohol consumption while taking R-Cin Suspension as it could lead to increased drowsiness, dizziness, and liver damage.

Uses of R-Cin Suspension

Treatment of Tuberculosis (TB)

Directions for Use

Tablet/Capsule: Take R-Cin Suspension 30 minutes before or 2 hours after food on an empty stomach. Swallow R-Cin Suspension as a whole; do not crush or chew the tablet/capsule. The dose and duration of R-Cin Suspension can vary depending on your condition and the severity of the infection.Dispersible tablet (DT): Before taking this, take a glass of water, disperse the tablet in it and then drink it.Suspension: Shake the bottle well. It can be taken 30 minutes before or 2 hours after food on an empty stomach. The dose and duration of R-Cin Suspension can vary depending on your condition and the severity of the infection.

Medicinal Benefits

R-Cin Suspension contains 'Rifampicin' that treats Tuberculosis (TB) by inactivating a bacterial genetic material that allows TB bacteria to make a copy of its protein for further growth inside the host cell (human). R-Cin Suspension is active against gram-positive cocci bacteria like Mycobacteria and Clostridium difficle and gram-negative bacteria like Neisseria meningitides, N. gonorrhoeae and Hemophilus influenzae. R-Cin Suspension is also used as a second-line treatment in the treatment of cholestatic pruritus. It also treats leprosy and severe gram-positive bacterial infections (like osteomyelitis, endocarditis, brain abscess, meningitis and implant infections) in combination with other antibiotics. 

How R-Cin Suspension Works

R-Cin Suspension consists of a drug called 'rifampicin', which works by inactivating a bacterial protein enzyme (RNA-polymerase) and inhibits bacterial cell death.  R-Cin Suspension acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight

Side Effects of R-Cin Suspension

  • Drowsiness
  • Dizziness 
  • Headache 
  • Weakness
  • Muscle pain
  • Heartburn 
  • Diarrhoea 
  • Gas 
  • Numbness or tingling sensation 

What if I have taken an overdose of R-Cin Suspension

Do not take more than the prescribed dose of R-Cin Suspension as it may cause overdose. The symptoms of overdose include stomach pain, itching, headache, nausea, vomiting, loss of consciousness, fast or irregular heartbeat, yellowing of the skin or eyes. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

R-Cin Suspension should be avoided if you are allergic to any of its contents. Inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems on priority before starting treatment with R-Cin Suspension . Avoid foods and drinks containing histamines or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while treating with R-Cin Suspension as they might cause interaction. Maintain a gap of one hour between R-Cin Suspension and antacid medicines.

R-Cin Suspension is not recommended for pregnant women. Hence, inform your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while using R-Cin Suspension as it passes into breast milk. R-Cin Suspension should be given to children only if prescribed by the paediatrician. R-Cin Suspension may cause dizziness or drowsiness, so avoid driving vehicles. Avoid alcohol consumption along with R-Cin Suspension as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

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RifampicinRanolazine
Critical
RifampicinPirfenidone
Critical

Drug-Drug Interactions

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RifampicinRanolazine
Critical
How does the drug interact with R-Cin Suspension 200 ml:
When ranolazine is taken with R-Cin Suspension 200 ml, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with R-Cin Suspension 200 ml:
Taking pirfenidone with R-Cin Suspension 200 ml can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with R-Cin Suspension 200 ml:
Taking Voriconazole with R-Cin Suspension 200 ml can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with R-Cin Suspension 200 ml, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinIndinavir
Critical
How does the drug interact with R-Cin Suspension 200 ml:
When Indinavir is taken with R-Cin Suspension 200 ml, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with R-Cin Suspension 200 ml:
Taking darunavir with R-Cin Suspension 200 ml can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with R-Cin Suspension 200 ml:
Taking saquinavir with R-Cin Suspension 200 ml can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinCariprazine
Severe
How does the drug interact with R-Cin Suspension 200 ml:
Taking cariprazine with R-Cin Suspension 200 ml can decrease the blood levels of cariprazine, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between cariprazine and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
RifampicinNifedipine
Severe
How does the drug interact with R-Cin Suspension 200 ml:
Coadministration of nifedipine with R-Cin Suspension 200 ml can decrease the blood levels of nifedipine, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between nifedipine and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinHaloperidol
Severe
How does the drug interact with R-Cin Suspension 200 ml:
Taking haloperidol with R-Cin Suspension 200 ml can decrease the blood levels of haloperidol.

How to manage the interaction:
Although there is an interaction between haloperidol and R-Cin Suspension 200 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
RifampicinKetoconazole
Severe
How does the drug interact with R-Cin Suspension 200 ml:
Taking ketoconazole and rifampin together can decrease the blood levels and effects of ketoconazole.

How to manage the interaction:
Co-administration of R-Cin Suspension 200 ml with Ketoconazole can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take foods rich in vitamin C such as orange, kiwi, broccoli, and bell pepper which helps in improving the immune system. 

  • Avoid consuming processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from cough.

  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.

  • Smoking and alcohol consumption should be avoided as it causes dizziness.

  • Drinking pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS
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Alcohol

Caution

R-Cin Suspension intake is not recommended with alcohol. A patient is not advised to take alcohol with R-Cin Suspension as it may increase chances of liver damage.

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Pregnancy

Unsafe

Not recommended during pregnancy. Tell your doctor if you are pregnant or planning to become pregnant. R-Cin Suspension should not be taken during pregnancy as it can affect your unborn baby's growth and may cause complications to the mother and baby after birth.

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Breast Feeding

Unsafe

Not recommended while breastfeeding. A patient should not breast-feed while taking R-Cin Suspension . This is because a small amount of R-Cin Suspension may pass into the mother’s milk. So, if you are breastfeeding or planning to breast-feed, talk to your doctor.

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Driving

Caution

Caution should be maintained by a patient while driving a motor vehicle or doing hazardous work. A patient may experience dizziness, have problems with vision or have other side effects that could affect his ability to drive after taking this medicine. If this happens, do not drive.

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Liver

Caution

Not recommended to be taken in liver patients without doctors consultation as R-Cin Suspension has been found to affect liver function with raised ALT enzymes.

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Kidney

Caution

Not recommended for kidney patients without doctor's consultation. Intake of R-Cin Suspension in these people may result in symptoms like blood in the urine, a change in the amount of urine passed and feeling drowsy or weak.

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Children

Safe if prescribed

R-Cin Suspension is safe to be prescribed in children below 12 years. Dose adjustments by the doctor are done according to age, weight, and severity of infection

FAQs

R-Cin Suspension belongs to the group of medicines called macrolide antibiotics, primarily used to treat tuberculosis (TB).
Do not stop taking R-Cin Suspension despite symptomatic relief. To treat your condition effectually, continue taking R-Cin Suspension for as long as it has been prescribed by doctor and must be taken strictly at proper times.
R-Cin Suspension is a bactericidal drug that means it kills bacteria. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for bacterial survival, thereby killing the bacteria.
R-Cin Suspension has no known serious drug interaction with ibuprofen or aspirin. Inform your doctor about all the medication you are currently taking to avoid harmful interactions that may reduce treatment effectiveness.
Yes, in some cases headache can be caused as a side effect of R-Cin Suspension . A patient must consult a doctor if it progresses with time.
R-Cin Suspension is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with R-Cin Suspension . Please consult your doctor if you have any liver problems before taking R-Cin Suspension as it may worsen the situation. However, prolonged use of R-Cin Suspension can cause raised ALT (liver enzyme), and the person taking the treatment can developed jaundice symptoms like yellowing of eye, skin etc. In this case, stop taking R-Cin Suspension and immediately contact a doctor.
R-Cin Suspension may cause temporary discoloration of urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Contact your doctor for further advice.
No, R-Cin Suspension is not a penicillin, amoxicillin, or sulfa drug. It is an antibiotic in the rifamycin class, combined with other medicines to treat tuberculosis.
R-Cin Suspension is an inducer (increases enzyme activity) of cytochrome P450 enzymes.
R-Cin Suspension may lead to side effects like weight loss, hair loss, and yeast infections, though constipation is less common. Consult your doctor if you experience any of these effects.
R-Cin Suspension causes side effects such as drowsiness, dizziness, headache, muscle pain, weakness, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please contact a doctor if these persist for longer periods.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0011

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