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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Razo IV Injection belongs to the class of proton pump inhibitors. It is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, and Zollinger-Ellison syndrome. It contains rabeprazole, which help decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, nausea, etc.
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Prescription drug

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Composition

RABEPRAZOLE-20MG

Manufacturer/Marketer

Dr Reddy's Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Razo IV Injection

Razo IV Injection is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.

Razo IV Injection contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump, which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

In some cases, you may experience certain common side effects, such as pain at the site of injection, diarrhoea, dizziness, dry mouth, headache, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

On long-term treatment, Razo IV Injection may cause low magnesium levels and vitamin B12 levels and increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Razo IV Injection may cause dizziness, so drive only if you are alert. Razo IV Injection is not recommended for children as safety has not been established. Avoid consuming alcohol along with Razo IV Injection as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Razo IV Injection

Treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, and Zollinger-Ellison syndrome

Medicinal Benefits

Razo IV Injection belongs to a group of antiulcer medicines called proton pump inhibitors. Razo IV Injection is used to treat gastric ulcers, duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome. Razo IV Injection works by blocking the action of the enzyme known as gastric proton pump, which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Directions for Use

Razo IV Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Razo IV Injection

  • Pain at the site of injection
  • Diarrhoea
  • Dry mouth
  • Dizziness
  • Headache
  • Abdominal pain

Drug Warnings

Do not take Razo IV Injection if you are allergic to any of its contents. Inform your doctor if you have a stomach tumour, liver disease, or if you are due to have Chromogranin A blood test. On long-term treatment, Razo IV Injection may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor before starting Razo IV Injection if you are pregnant or breastfeeding. Razo IV Injection may cause dizziness, so drive only if you are alert. Razo IV Injection is not recommended for children as safety has not been established. Avoid consuming alcohol along with Razo IV Injection as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug Interactions

Drug-Drug Interactions: Razo IV Injection may have interaction with an anti-retroviral agent (atazanavir), anti-fungal (ketoconazole, itraconazole), anti-rheumatic (methotrexate).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Drug-Disease Interactions: Inform your doctor if you have Clostridium difficile-associated diarrhoea, liver disease, bone fractures, and hypomagnesemia (low levels of magnesium).

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Special Advise

  • Inform your doctor before taking Razo IV Injection if you are due to have Chromogranin A blood test.
  • Razo IV Injection may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Razo IV Injection.
  • Razo IV Injection may increase the risk of infections. Consult your doctor if you notice any signs or symptoms of infections.

Disease/Condition Glossary

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger-Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Gastric/duodenal ulcer: It is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining.

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production, leading to peptic ulcers.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Razo IV Injection. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Razo IV Injection.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Razo IV Injection can be taken by breastfeeding mothers or not.

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Driving

Caution

Razo IV Injection may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Razo IV Injection is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - RAZ0008

Author Details

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FAQs

Razo IV Injection is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.
Razo IV Injection works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
Diarrhoea might be a side-effect of Razo IV Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Razo IV Injection is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.
Dry mouth could be a side-effect of Razo IV Injection. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
On long-term treatment, Razo IV Injection might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.
Razo IV Injection may increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice any signs of increased bleeding or bruising.

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