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Last Updated Jan 17, 2025 | 7:41 AM IST

Rasilez-Hct 150mg/12.5mg Tablet is used to treat high blood pressure (hypertension) in patients who require combination therapy. It is a combination medication consisting of Aliskiren and Hydrochlorothiazide. Aliskiren lowers blood pressure by relaxing the blood vessels, making blood flow easier. Hydrochlorothiazide lowers blood volume by promoting salt and water excretion through urine, which further helps lower blood pressure. Sometimes, you may experience common side effects such as diarrhoea, dizziness, tiredness, high potassium levels (hyperkalaemia), low blood pressure (hypotension), dehydration, dry cough, joint pain, and flu-like symptoms. If you are allergic to any of its ingredients, are pregnant or breastfeeding, are taking other medications, or have any pre-existing medical conditions, inform your doctor before starting Rasilez-Hct 150mg/12.5mg Tablet.

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Prescription drug

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Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Rasilez-Hct 150mg/12.5mg Tablet

Rasilez-Hct 150mg/12.5mg Tablet is used to treat high blood pressure (hypertension) in patients who require combination therapy. It is not intended as a first-line treatment but rather to replace individual tablets of Aliskiren and Hydrochlorothiazide for patients already taking these medications at the same dose. Hypertension is a chronic condition in which blood exerts increased pressure on the walls of the arteries (blood vessels).

Rasilez-Hct 150mg/12.5mg Tablet is a combination of two drugs: Aliskiren (a direct renin inhibitor) and Hydrochlorothiazide (a diuretic/water pill). Aliskiren works by inhibiting the action of renin, an enzyme that helps the body produce angiotensin I, which is then converted to angiotensin II (a hormone that tightens and narrows blood vessels, increasing blood pressure). By reducing the production of angiotensin I and II, Aliskiren helps relax and widen blood vessels, thereby lowering blood pressure. Hydrochlorothiazide works by blocking the reabsorption of sodium and chloride in the kidneys, which leads to increased excretion of these electrolytes along with water. This reduces the overall fluid volume in the blood vessels, which in turn lowers blood pressure. Together, these drugs work effectively to reduce high blood pressure.

Take Rasilez-Hct 150mg/12.5mg Tablet as prescribed. Your doctor will advise you on how often to take Rasilez-Hct 150mg/12.5mg Tablet based on your medical condition. In some cases, you may experience common side effects such as diarrhoea, dizziness, tiredness, high potassium levels (hyperkalaemia), low blood pressure (hypotension), dehydration, dry cough, joint pain, and flu-like symptoms. Most of these side effects of Rasilez-Hct 150mg/12.5mg Tablet gradually resolve over time and do not require medical attention. However, if any of these side effects persist or worsen, please consult your doctor.

Before taking Rasilez-Hct 150mg/12.5mg Tablet, inform your doctor if you are allergic to Aliskiren or any other ingredients in Rasilez-Hct 150mg/12.5mg Tablet, or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, which may cause difficulty breathing) to an ACE (angiotensin-converting enzyme) inhibitor medicine. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause fatal harm to the developing baby. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for children and adolescents under 18 years of age, as its safety and effectiveness have not been established.

Uses of Rasilez-Hct 150mg/12.5mg Tablet

Rasilez-Hct 150mg/12.5mg Tablet is used in the treatment of high blood pressure (hypertension) in patients who require combination therapy.

Medicinal Benefits

Rasilez-Hct 150mg/12.5mg Tablet belongs to a class of medications called 'anti-hypertensives,' primarily used to treat mild to moderate high blood pressure (hypertension) in patients who require combination therapy. It contains two medications: Aliskiren and Hydrochlorothiazide. This medication is not intended to be used as a first-line treatment but rather to replace individual tablets of Aliskiren and Hydrochlorothiazide for patients already taking these medications at the same dose. Aliskiren lowers blood pressure by relaxing the blood vessels, making blood flow easier. Hydrochlorothiazide lowers blood volume by promoting salt and water excretion through urine, which further helps lower blood pressure. Together, these drugs work effectively to reduce high blood pressure, thereby lowering the risk of heart failure, stroke, heart attack, or kidney failure.

Side Effects of Rasilez-Hct 150mg/12.5mg Tablet

  • Diarrhoea
  • Dizziness
  • Tiredness
  • High potassium levels (hyperkalaemia)
  • Low blood pressure (hypotension)
  • Dehydration
  • Dry cough
  • Joint pain
  • Flu-like symptoms

Directions for Use

Take Rasilez-Hct 150mg/12.5mg Tablet as advised by your doctor. Swallow it as a whole with a glass of water daily at the same time for effective results. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Rasilez-Hct 150mg/12.5mg Tablet, inform your doctor if you are allergic to Aliskiren or any other ingredients in Rasilez-Hct 150mg/12.5mg Tablet or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, which may cause difficulty breathing) to an ACE (angiotensin-converting enzyme) inhibitor medicine. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause fatal harm to the developing baby. It is also not recommended for breastfeeding women, as it is excreted into breast milk. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Rasilez-Hct 150mg/12.5mg Tablet. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for children under 18 years of age, as its safety and effectiveness have not been established. Do not take Rasilez-Hct 150mg/12.5mg Tablet if you have severe and persistent diarrhoea, anuria (no urine output), galactose intolerance, low sodium (hyponatremia), low calcium (hypocalcaemia), low potassium (hypokalaemia), or high serum uric acid levels (hyperuricemia). Avoid potassium supplements while taking Rasilez-Hct 150mg/12.5mg Tablet, as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure (hypotension), difficulty urinating, gout (buildup of urate crystals in joints), blood disorders, systemic lupus erythematosus (an autoimmune disease), cerebrovascular disease (a condition affecting blood flow to the brain), a history of angioedema (swelling under the skin), or kidney, liver, or heart problems, inform your doctor before taking Rasilez-Hct 150mg/12.5mg Tablet.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

verifiedApollotooltip
AliskirenValsartan
Critical
AliskirenPerindopril
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize the consumption of processed foods, as they contain more sodium. Try replacing salt with herbs or spices to add flavour to your food.
  • Do regular exercise, such as walking, jogging, cycling, dancing, or swimming, for at least 30 minutes per day.
  • Chronic stress may also contribute to high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and engage in activities that you enjoy.
  • Try to follow the Dietary Approaches to Stop Hypertension (DASH) diet, which includes foods such as fruits, vegetables, whole grains, poultry, fish, and low-fat dairy.
  • Increase your potassium intake from natural sources, which may help lower blood pressure.
  • Try to include omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils, such as soybean oil, olive oil, canola oil, and coconut oil, which may help lower high blood pressure.
  • Quit smoking and avoid alcohol consumption.
     

Habit Forming

No

How Rasilez-Hct 150mg/12.5mg Tablet Works

Rasilez-Hct 150mg/12.5mg Tablet is a combination of two drugs: Aliskiren (a direct renin inhibitor) and Hydrochlorothiazide (a diuretic/water pill). Aliskiren works by inhibiting the action of renin, an enzyme that helps the body produce angiotensin I, which is then converted to angiotensin II (a hormone that tightens and narrows blood vessels, increasing blood pressure). By reducing the production of angiotensin I and II, Aliskiren helps relax and widen blood vessels, thereby lowering blood pressure. Hydrochlorothiazide works by blocking the reabsorption of sodium and chloride in the kidneys, which leads to increased excretion of these electrolytes along with water. This reduces the overall fluid volume in the blood vessels, which in turn lowers blood pressure. Together, these drugs work effectively to reduce high blood pressure.

What if I have taken an overdose of Rasilez-Hct 150mg/12.5mg Tablet

Do not take more than the prescribed dose of Rasilez-Hct 150mg/12.5mg Tablet, as it may cause an overdose. Symptoms of an overdose include low blood pressure (hypotension), electrolyte imbalances (low levels of potassium, chloride, and sodium), and dehydration. If you suspect you have taken an overdose or notice any unusual symptoms, please seek medical help from a doctor immediately.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Rasilez-Hct 150mg/12.5mg Tablet as it may worsen low blood pressure.

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Pregnancy

Unsafe

Rasilez-Hct 150mg/12.5mg Tablet is not recommended for use during pregnancy, especially in the second and third trimesters, as it may cause injury and death to the developing fetus. So when pregnancy is detected, Rasilez-Hct 150mg/12.5mg Tablet should be discontinued as soon as possible.

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Breast Feeding

Unsafe

Rasilez-Hct 150mg/12.5mg Tablet contains Hydrochlorothiazide which passes into breast milk. You are recommended to avoid breastfeeding while taking Rasilez-Hct 150mg/12.5mg Tablet.

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Driving

Caution

Rasilez-Hct 150mg/12.5mg Tablet may cause dizziness or lightheadedness. So, avoid driving or operating machinery until you are fully alert after taking Rasilez-Hct 150mg/12.5mg Tablet.

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Liver

Consult your doctor

If you have a pre-existing liver disease, inform your doctor before taking Rasilez-Hct 150mg/12.5mg Tablet.

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Kidney

Caution

If you have a pre-existing kidney disease, inform your doctor before taking Rasilez-Hct 150mg/12.5mg Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Rasilez-Hct 150mg/12.5mg Tablet is not recommended for children under 18 years of age, as its safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - RAS0027

FAQs

Rasilez-Hct 150mg/12.5mg Tablet is used in the treatment of high blood pressure (hypertension) in patients who require combination therapy. This medication is not intended to be used as a first-line treatment but rather to replace individual tablets of Aliskiren and Hydrochlorothiazide for patients already taking these medications at the same dose.
Rasilez-Hct 150mg/12.5mg Tablet is a combination of two drugs: Aliskiren and Hydrochlorothiazide. Aliskirens work by relaxing and widening blood vessels, thereby lowering blood pressure. Hydrochlorothiazide works by blocking the reabsorption of sodium and chloride in the kidneys, which leads to increased excretion of these electrolytes along with water. This reduces the blood vessels' overall fluid volume, which lowers blood pressure. Together, these drugs work effectively to reduce high blood pressure.
The common side effects of Rasilez-Hct 150mg/12.5mg Tablet include diarrhoea, dizziness, tiredness, high potassium levels (hyperkalaemia), low blood pressure (hypotension), dehydration, dry cough, joint pain, and flu-like symptoms. Most of these side effects gradually resolve over time and do not require medical attention. However, if any of these side effects persist or worsen, please consult your doctor.
You are not recommended to take potassium supplements with Rasilez-Hct 150mg/12.5mg Tablet, as this may increase potassium levels in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines or supplements with Rasilez-Hct 150mg/12.5mg Tablet.
Rasilez-Hct 150mg/12.5mg Tablet usually begins to work within two weeks after starting the treatment. However, seeing the full benefits may take up to 4 weeks. Therefore, it is important to continue taking Rasilez-Hct 150mg/12.5mg Tablet for the duration prescribed by your doctor to prevent recurring symptoms.
Yes, Rasilez-Hct 150mg/12.5mg Tablet may cause fluid and electrolyte imbalance. Symptoms include dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pain or cramps, muscular fatigue, hypotension, nausea and vomiting. If you experience any of these symptoms, please consult your doctor. It is important to monitor your electrolyte levels and stay hydrated while taking Rasilez-Hct 150mg/12.5mg Tablet.
Joint pain is a common side effect of Rasilez-Hct 150mg/12.5mg Tablet. To manage this side effect, maintain a healthy weight and try light exercise or physical therapy to strengthen the muscles around the affected joint. If the joint pain persists or worse, please consult your doctor.
Yes, Rasilez-Hct 150mg/12.5mg Tablet can cause dizziness as a side effect. If you experience dizziness, it is important to sit or lie down until the symptoms disappear. Always carry fruit juice or sugary food with you if you experience dizziness while travelling. Additionally, avoid driving or operating heavy machinery or engaging in activities that require mental alertness until you know how Rasilez-Hct 150mg/12.5mg Tablet affects you.
Rasilez-Hct 150mg/12.5mg Tablet is contraindicated in patients who are allergic to Aliskiren or any other ingredients in Rasilez-Hct 150mg/12.5mg Tablet, or who have had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, which may cause difficulty breathing) to an ACE (angiotensin-converting enzyme) inhibitor medicine. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for pregnant women, especially during the second and third trimesters, as it may cause fatal harm to the developing baby. It is also not recommended for breastfeeding women, as it is excreted into breast milk. Rasilez-Hct 150mg/12.5mg Tablet is not recommended for children under 18 years of age, as its safety and effectiveness have not been established. Additionally, do not take Rasilez-Hct 150mg/12.5mg Tablet if you have severe and persistent diarrhoea, galactose intolerance, low sodium (hyponatremia), low calcium (hypocalcaemia), low potassium (hypokalaemia), or high serum uric acid levels (hyperuricemia), anuria (no urine output), and severe kidney disease.

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