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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ranx 1000 mg Tablet is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

RANOLAZINE-1000MG

Manufacturer/Marketer :

Unichem International

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ranx 1000 mg Tablet

Ranx 1000 mg Tablet is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Ranx 1000 mg Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranx 1000 mg Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Ranx 1000 mg Tablet based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Ranx 1000 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Ranx 1000 mg Tablet if you are allergic to any component in this medicine. Ranx 1000 mg Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ranx 1000 mg Tablet on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Ranx 1000 mg Tablet , like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Ranx 1000 mg Tablet should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Ranx 1000 mg Tablet

Treatment of Angina Pectoris.

Directions for Use

Swallow Ranx 1000 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Ranx 1000 mg Tablet is prescribed for treating angina. Ranx 1000 mg Tablet is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranx 1000 mg Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

How Ranx 1000 mg Tablet Works

The active substance in Ranx 1000 mg Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranx 1000 mg Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ranx 1000 mg Tablet

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

What if I have taken an overdose of Ranx 1000 mg Tablet

Do not take more than the prescribed dose of Ranx 1000 mg Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Ranx 1000 mg Tablet should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Ranx 1000 mg Tablet . As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug-Drug Interactions

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RanolazineVoriconazole
Critical
RanolazineRifapentine
Critical

Drug-Drug Interactions

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RanolazineVoriconazole
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
Co-administration of Ranx 1000 mg Tablet 10's together with Voriconazole may significantly increase the blood levels and effects of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Taking Ranx 1000 mg Tablet 10's with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.
RanolazineRifapentine
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Ranx 1000 mg Tablet 10's is taken with Rifapentine, may significantly reduce the blood levels of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Taking Ranx 1000 mg Tablet 10's with Rifapentine together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
RanolazineThioridazine
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Thioridazine is taken with Ranx 1000 mg Tablet 10's, may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ranx 1000 mg Tablet 10's with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazinePhenobarbital
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Ranx 1000 mg Tablet 10's is taken with Phenobarbital, may significantly reduce the blood levels of Ranx 1000 mg Tablet 10's, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with Ranx 1000 mg Tablet 10's can lead to an interaction, consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineEfavirenz
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Efavirenz is taken with Ranx 1000 mg Tablet 10's, it can lower the levels of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Taking Ranx 1000 mg Tablet 10's with Efavirenz is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
RanolazineNafcillin
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Nafcillin is taken with Ranx 1000 mg Tablet 10's, may significantly reduce the blood levels of Ranx 1000 mg Tablet 10's, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Nafcillin with Ranx 1000 mg Tablet 10's can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
RanolazineClarithromycin
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Ranx 1000 mg Tablet 10's and Clarithromycin are taken together, significantly increases the blood levels and effects of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Co-administration of Clarithromycin and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
RanolazinePrimidone
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
Coadministration of Ranx 1000 mg Tablet 10's with primidone can reduce the blood levels and effects of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Although there is an interaction between Primidone and Ranx 1000 mg Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazinePhenylbutazone
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
Co-administration of Phenylbutazone and Ranx 1000 mg Tablet 10's may significantly reduce the blood levels of Ranx 1000 mg Tablet 10's, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenylbutazone with Ranx 1000 mg Tablet 10's can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineCeritinib
Critical
How does the drug interact with Ranx 1000 mg Tablet 10's:
When Ceritinib is taken with Ranx 1000 mg Tablet 10's, may significantly increase the blood levels and effects of Ranx 1000 mg Tablet 10's.

How to manage the interaction:
Taking Ranx 1000 mg Tablet 10's with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any side effects like lightheadedness, fainting, dizziness, or fast or pounding heartbeats, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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RANOLAZINE-1000MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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RANOLAZINE-1000MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Ranx 1000 mg Tablet 10's, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Ranx 1000 mg Tablet 10's if possible.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.

  • If you suffer from kidney or liver disease, please inform your doctor before taking the Ranx 1000 mg Tablet .
  • Alcohol consumption along with Ranx 1000 mg Tablet should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Ranx 1000 mg Tablet Substitute

Substitutes safety advice
  • Ranolaz OD Tablet 10's

    26.91per tablet
  • Rancv 1000 Tablet 10's

    by AYUR

    16.97per tablet
  • Rancad 1000 Tablet 10's

    by AYUR

    26.62per tablet
  • Ranozex 1 gm Tablet 10's

    17.91per tablet
  • Revulant 1000 mg Tablet 10's

    10.35per tablet
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Alcohol

Safe if prescribed

Ranx 1000 mg Tablet does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

bannner image

Pregnancy

Unsafe

Ranx 1000 mg Tablet should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ranx 1000 mg Tablet .

bannner image

Breast Feeding

Unsafe

Ranx 1000 mg Tablet should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

bannner image

Driving

Safe if prescribed

Ranx 1000 mg Tablet does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

bannner image

Liver

Caution

Ranx 1000 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Ranx 1000 mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Ranx 1000 mg Tablet is not recommended for children below the age of 18. The safety and effectiveness of Ranx 1000 mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

FAQs

Ranx 1000 mg Tablet is used alone or with other medicines to treat angina pectoris.
The active substance in Ranx 1000 mg Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranx 1000 mg Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.
No, Ranx 1000 mg Tablet does not stop acute attacks (sudden attacks) of angina, but Ranx 1000 mg Tablet helps prevent a new attack.
No, alcohol should not be taken with Ranx 1000 mg Tablet as it may lead to unwanted side effects and increase angina attacks.
Yes, smoking (tobacco) decreases the efficacy of Ranx 1000 mg Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Ranx 1000 mg Tablet .
Yes, Ranx 1000 mg Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Ranx 1000 mg Tablet should be taken with a meal for best results.
Yes, Ranx 1000 mg Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.
Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.
Do not take more than the prescribed dose of Ranx 1000 mg Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Ranx 1000 mg Tablet may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.
Ranx 1000 mg Tablet might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.
You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Ranx 1000 mg Tablet .

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - RAN0124

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