Rani 150mg Tablet is used to treat indigestion, heartburn and acid reflux. Rani 150mg Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Rani 150mg Tablet is also used to prevent and treat stomach ulcers. Often, Rani 150mg Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Rani 150mg Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall. It is responsible for the release of gastric acid secretion - extra gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Take this medication exactly as prescribed by your doctor. It would help if you kept taking medicine for as long as your doctor recommends. If you stop early, your symptoms may come back, and your condition may worsen. Rani 150mg Tablet might have common side effects like headache, diarrhoea, constipation, and shortness of breath. These side effects are temporary and may be resolved after some time. However, if these side effects persist, contact your doctor.

It is recommended not to take Rani 150mg Tablet if you are allergic to any components present in Rani 150mg Tablet. If you are pregnant, planning to become pregnant, or are breastfeeding, you should not take this medication unless your doctor says it is necessary. Inform your doctor if you have stomach or intestinal cancer, liver problem, or will have an endoscopy in the future. Also, let your doctor know about your health condition and all the medicines you are taking before taking Rani 150mg Tablet to rule out any side effects.

Rani 150mg Tablet helps in reducing the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger-Ellison Syndrome, in which the stomach makes an exceptionally high amount of acid.

• Headache

• Constipation

• Diarrhoea

• Stomach pain

You should avoid taking Rani 150mg Tablet if you are allergic to Rani 150mg Tablet or H2 receptor blockers, have gastric cancer, or have liver disease. If you are a pregnant woman or nursing mother, do not consume Rani 150mg Tablet without first consulting your doctor. Rani 150mg Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), or anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines. Intake of Rani 150mg Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous), immediately consult the doctor.

Drug-Drug Interactions:Rani 150mg Tablet interacts with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir), and antacid (aluminium hydroxide).

Drug-Food Interactions: Drinking alcohol and nicotine (tobacco) with Rani 150mg Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy.

Drug-Disease Interactions: Rani 150mg Tablet interacts with disease conditions, including gastric bleeding, liver/ kidney disease, and low vitamin B12 (anaemia).

• WARFARIN
• KETOCONAZOLE
• ATAZANAVIR
• ALUMINUM HYDROXIDE

• Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.

• Before going to sleep, raise your bedhead, so your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.

• Avoid taking alcohol and smoking cigarettes. Alcohol can raise the production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.

• Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal.

• Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infections.

• Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

The stomach is usually protected from acid by a mucous layer. In some cases, excess acid production erodes the mucous layer, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting.

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets irritated or eroded due to excess acid production, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.