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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ramipres-H Tablet is prescribed alone or in combination with other drugs to lower the raised blood pressure. It contains Ramipril and Hydrochlorothiazide, which relaxes the blood vessels and therefore helps lower high blood pressure. Also, it works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Sometimes, you may experience side effects such as headaches, tiredness, slow heart rate, and nausea.
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ramipres-H Tablet

Ramipres-H Tablet is prescribed alone or in combination with other drugs to lower the raised blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Ramipres-H Tablet contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes. 

You can take Ramipres-H Tablet with a meal or after/before a meal. Your doctor will advise you on the exact dosage and how often you have to take Ramipres-H Tablet based on your medical condition. Sometimes, you may experience headaches, tiredness, slow heart rate, and nausea. Most of these side effects of Ramipres-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Ramipres-H Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery.

Try not to stop taking this medicine of your own. You should not stop using the Ramipres-H Tablet even if your blood pressure becomes normal. Doing so may worsen your condition. Tell your doctor if you have had or currently have liver, kidney, or heart problems. Ramipres-H Tablet is not recommended in pregnancy and lactation. You should regularly monitor your blood pressure and heart rate. Please tell your doctor if you are taking any other medicines or are allergic to Ramipres-H Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Ramipres-H Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow Ramipres-H Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Ramipres-H Tablet contains Ramipril and hydrochlorothiazide. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing the chances of heart attack or stroke. However, Ramipres-H Tablet does not cure high blood pressure (hypertension) but does help control it. In addition to this, Ramipres-H Tablet also reduces the physical effects of anxiety.

How Ramipres-H Tablet Works

Ramipres-H Tablet contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ramipres-H Tablet

  • Feeling dizzy or lightheaded
  • Headache
  • Diarrhoea
  • Being sick
  • Mild skin rash
  • Blurred vision
  • Hypotension
  • Nausea (feeling sick)

What if I have taken an overdose of Ramipres-H Tablet

Do not take more than the prescribed dose of Ramipres-H Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Ramipres-H Tablet should not be given to the people allergic to Ramipres-H Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, diabetes, kidney disease, liver disease, are pregnant women, or planning to get pregnant and breastfeeding women. Ramipres-H Tablet may alter your blood sugar level, so tell your doctor about this before using Ramipres-H Tablet . Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), and aortic stenosis (heart valve problem). Ramipres-H Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Ramipres-H Tablet and breastfeeding. Do not consume alcohol with Ramipres-H Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Ramipres-H Tablet as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking Ramipres-H Tablet . Drink a lot of fluids as Ramipres-H Tablet can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
RamiprilTrimethoprim
Severe

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Ramipres-H Tablet:
Taking aliskiren together with Ramipres-H Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Ramipres-H Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
RamiprilTrimethoprim
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Ramipres-H Tablet with Trimethoprim can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Ramipres-H Tablet and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
RamiprilPotassium acetate
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Ramipres-H Tablet with potassium acetate may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm

How to manage the interaction:
Although there is a interaction between Ramipres-H Tablet and Potassium acetate, but it can be taken if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilKetoconazole
Severe
How does the drug interact with Ramipres-H Tablet:
Coadministration of Ramipres-H Tablet with ketoconazole may increase the blood level of Ramipres-H Tablet.

How to manage the interaction:
Although taking Ramipres-H Tablet with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
RamiprilIrbesartan
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Ramipres-H Tablet together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Ramipres-H Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
RamiprilPotassium iodide
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Potassium Iodide with Ramipres-H Tablet may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Potassium iodide and Ramipres-H Tablet, you can take these medicines together if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilOlmesartan medoxomil
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Ramipres-H Tablet together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking olmesartan medoxomil with Ramipres-H Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
RamiprilValsartan
Severe
How does the drug interact with Ramipres-H Tablet:
Taking Ramipres-H Tablet with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Ramipres-H Tablet together with Valsartan can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting a doctor.
RamiprilAllopurinol
Severe
How does the drug interact with Ramipres-H Tablet:
Co-administration of Allopurinol with Ramipres-H Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Ramipres-H Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
RamiprilSpironolactone
Severe
How does the drug interact with Ramipres-H Tablet:
Using Ramipres-H Tablet together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium-rich foods while using Ramipres-H Tablet may increase the potassium levels in your blood. It is recommended to avoid potassium-rich foods while using Ramipres-H Tablet. If you experience a fast heartbeat, shortness of breath, chest pain, nausea, or vomiting, consult your doctor immediately.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.

  • Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.

  • Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Ramipres-H Tablet Substitute

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Alcohol

Unsafe

Ramipres-H Tablet may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with. For better advice, you should consult your doctor about whether you can take Ramipres-H Tablet with alcohol.

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Pregnancy

Unsafe

The use of Ramipres-H Tablet or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Ramipres-H Tablet .

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Breast Feeding

Caution

Use of Ramipres-H Tablet is not recommended during the breastfeeding stage.

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Driving

Unsafe

Drive with caution, Ramipres-H Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking Ramipres-H Tablet , so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Ramipres-H Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Ramipres-H Tablet should be given with precaution in hemodialysis condition.

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Children

Caution

Ramipres-H Tablet is not recommended for children. The safety and effectiveness of Ramipres-H Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Ramipres-H Tablet or not.

FAQs

Ramipres-H Tablet is used to treat Hypertension (High blood pressure).

Usually, Ramipres-H Tablet is prescribed for a long-term treatment ranging from weeks to months or for life long also for treating lowering raised blood pressure, swelling due to fluid overload (oedema) and heart-related conditions. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor prescribes it.

Yes, Ramipres-H Tablet can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Ramipres-H Tablet . In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

If you forget to take Ramipres-H Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Yes, in some cases, Ramipres-H Tablet may affect your serum potassium level, so consult your doctor before using potassium supplements or its salt substitutes.

Ramipres-H Tablet should not be used if you have a history of a serious allergic reaction, including swelling of the face/lips/tongue/throat (angioedema) and an inability to make urine. Besides this, if you are using alcohol or recreational drugs, do not do hazardous work like driving a motor vehicle or operating heavy machinery. Before going outdoor in the sun, try to wear sunscreen (SPF) and avoid sunlamps and tanning booths as prolonged intake of Ramipres-H Tablet may cause your skin to be sensitive to the sunlight.

Yes, if you have diabetes, Ramipres-H Tablet may change your blood sugar level, so check your blood sugar regularly as directed. Tell your doctor if you have high blood sugar (hyperglycemia) symptoms like increased thirst/urination or signs of low blood sugar (hypoglycemia) such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor might adjust your dose of Ramipres-H Tablet .

Ramipres-H Tablet contains Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretics or water pills). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes. 

The common side effects of Ramipres-H Tablet include headaches, tiredness, slow heart rate, and nausea. Most of these side effects gradually resolve over time; however, if they persist, please inform your doctor.

No, you should not stop treatment with Ramipres-H Tablet even if you feel an improvement in your symptoms because high blood pressure often has no symptoms and can shoot up at any time. Continue taking it for as long as it has been advised by your doctor.

Yes, you can take Ramipres-H Tablet every day if advised by the doctor. Just make sure to follow your doctor’s instructions regarding how long to use it. Taking it for years on your own without your doctor’s approval could be fatal.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - RAM0026

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