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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Raciwel 250 Injection 5 ml is used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. It contains Fluorouracil which works by preventing the cancer cells from multiplying and eventually kills them. In some cases, this medicine may cause side effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells, and mouth ulcers. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Raciwel 250 Injection 5 ml

Raciwel 250 Injection 5 ml belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. Cancer is a disease in which cells divide uncontrollably. Cancer can be localized (benign) or spread to the whole body (metastasized). 

Raciwel 250 Injection 5 ml contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

In some cases, Raciwel 250 Injection 5 ml may cause nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells, and mouth ulcers. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Avoid taking Raciwel 250 Injection 5 ml if you are pregnant or breastfeeding. Both women and men on treatment with Raciwel 250 Injection 5 ml should use birth control to avoid pregnancy. 

Uses of Raciwel 250 Injection 5 ml

Treatment of Breast, colon, rectum, pancreatic and stomach/gastric cancer

Medicinal Benefits

Raciwel 250 Injection 5 ml belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. Raciwel 250 Injection 5 ml contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

Directions for Use

It will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Raciwel 250 Injection 5 ml

  • Nausea
  • Vomiting
  • Weakness
  • Loss of appetite
  • Increased risk of infection
  • Hair loss
  • Diarrhoea
  • Decreased blood cells 
  • Mouth ulcer

Drug Warnings

Inform your doctor if you have any infection, a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Consult your doctor if you are pregnant because Raciwel 250 Injection 5 ml can cause harmful effects on the unborn baby. Women and men using Raciwel 250 Injection 5 ml should use birth control to avoid pregnancy. The use of Raciwel 250 Injection 5 ml by either parent may result in congenital disabilities. Raciwel 250 Injection 5 ml should be used with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy.

Drug Interactions

Drug-Drug Interactions: Raciwel 250 Injection 5 ml interacts with other anti-cancer medicines (methotrexate, cisplatin, cytarabine, mitomycin-C, tamoxifen), antibiotics (metronidazole), medicines used to reduce the harmful effects of anti-cancer medicines (calcium leucovorin), a medicine used to treat gout (allopurinol), a medicine used to treat stomach ulcers (cimetidine), blood thinner (warfarin), antivirals (interferon-alpha 2a, brivudine, sorivudine), anti-epilepsy medicine (phenytoin), vaccines (rubella, mumps, measles, BCG, shingles).

Drug-Food Interactions: No interaction was found.

Drug-Disease Interactions: Inform your doctor if you have myelosuppression (bone marrow activity is decreased), dihydropyrimidine dehydrogenase (DPD) enzyme deficiency, stomatitis, infections, bleeding disorder or coronary artery disease.

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • CISPLATIN
  • CYTARABINE
  • MITOMYCIN
  • TAMOXIFEN
  • METRONIDAZOLE
  • ALLOPURINOL
  • CIMETIDINE
  • WARFARIN
  • INTERFERON ALFA
  • PHENYTOIN
  • RUBELLA (LIVE ATTENUATED)
  • MUMPS (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)
  • BACILLUS CALMETTE-GUERIN(BCG) VACCINE
  • SHINGLES VACCINE
  • CALCIUM LEUCOVORIN
  • BRIVUDINE
  • SORIVUDINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

  • Get optimal sleep, and rest well.

Special Advise

  • Your doctor may suggest routine blood tests to monitor your liver function, electrolyte levels, and blood cell count.

  • Consult a doctor immediately if you notice any signs of infection, fever, diarrhoea, chills, etc.

  • Women of childbearing potential and men with partners of childbearing potential must use an effective method of contraception while on treatment with Raciwel 250 Injection 5 ml and for at least three months afterwards. Please consult your doctor for any concerns regarding this.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Stomach Cancer (gastric cancer): It is a type of cancer that develops from the stomach lining. Risk factors may include smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori.  Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while on treatment with Raciwel 250 Injection 5 ml to prevent unpleasant side effects. Alcohol intake, along with Raciwel 250 Injection 5 ml, may cause increased drowsiness.

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Pregnancy

Unsafe

It is not recommended for pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Raciwel 250 Injection 5 ml.

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Breast Feeding

Unsafe

It is not recommended for breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Raciwel 250 Injection 5 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Safe

Raciwel 250 Injection 5 ml does not affect your driving ability.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Raciwel 250 Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Raciwel 250 Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Raciwel 250 Injection 5 ml is not recommended for children, as efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

305, Bakshi House, 40-41, Nehru Place ., New Delhi- 110 017
Other Info - RAC0112

FAQs

Raciwel 250 Injection 5 ml is used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer.
Raciwel 250 Injection 5 ml works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Yes, Raciwel 250 Injection 5 ml affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Raciwel 250 Injection 5 ml. These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.
Yes, Raciwel 250 Injection 5 ml may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Raciwel 250 Injection 5 ml.
$nanme might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Raciwel 250 Injection 5 ml. However, it is essential to talk to your doctor before starting treatment with Raciwel 250 Injection 5 ml if you think you may want to have a baby in the future.

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