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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Rabium Plus Capsule is used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. It contains Rabeprazole and Itopride, which blocks acid production and provides relief from heartburn and acid-related digestion. Also, it works on the part of the brain that is responsible for controlling vomiting. It increases the movement of stomach and intestines in the upper digestive tract. Thus, it helps prevent acid reflux, thereby relieving acidity. Sometimes, it may cause common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Rabium Plus Capsule

Rabium Plus Capsule is used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Rabium Plus Capsule is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain that is responsible for controlling vomiting.  It increases gastric emp undying improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabium Plus Capsule helps prevent acid reflux, thereby relieving acidity.

Take Rabium Plus Capsule 30-60 minutes before food. Do not chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take Rabium Plus Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Rabium Plus Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, Rabium Plus Capsule may cause osteoporosis and hypomagnesemia (low levels of magnesium). Do not take Rabium Plus Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Rabium Plus Capsule causes drowsiness, so drive only if you are alert. Rabium Plus Capsule should not be given to children as safety has not been established. Avoid consuming alcohol with Rabium Plus Capsule as it can lead to increased drowsiness and increased acid production. 

Uses of Rabium Plus Capsule

Treatment of Hyperacidity, Gastro-oesophageal reflux disease, Peptic ulcer.

Directions for Use

Take this medicine 30-60 minutes before food. Do not chew or crush it; swallow it as a whole with a glass of water. Depending on your medical condition, your doctor will decide how long you need to take this medicine.

Medicinal Benefits

Rabium Plus Capsule is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabium Plus Capsule helps prevent acid reflux, thereby relieving acidity.
 

How Rabium Plus Capsule Works

Rabium Plus Capsule is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabium Plus Capsule helps prevent acid reflux, thereby relieving acidity.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rabium Plus Capsule

  • Nausea
  • Dizziness
  • Diarrhoea 
  • Headache
  • Stomach pain

What if I have taken an overdose of Rabium Plus Capsule

Do not take more than the prescribed dose of Rabium Plus Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Rabium Plus Capsule if you are allergic to any of its contents. Inform your doctor before taking Rabium Plus Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. Rabium Plus Capsule may cause osteoporosis on long-term treatment. Rabium Plus Capsule may also cause hypomagnesemia (low magnesium). Do not take Rabium Plus Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Rabium Plus Capsule causes dizziness, so drive only if you are alert. Rabium Plus Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Rabium Plus Capsule as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.  Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Rabium Plus Capsule may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Rabium Plus Capsule 10's:
When used in combination with erlotinib, Rabium Plus Capsule 10's may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Rabium Plus Capsule 10's with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Rabium Plus Capsule 10's:
Co-administration of Rabium Plus Capsule 10's can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rabium Plus Capsule 10's with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleMethotrexate
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Co-administration of Methotrexate with Rabium Plus Capsule 10's can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Rabium Plus Capsule 10's and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleDasatinib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Taking Dasatinib with Rabium Plus Capsule 10's may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Rabium Plus Capsule 10's with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
RabeprazoleGefitinib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Taking Rabium Plus Capsule 10's together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Rabium Plus Capsule 10's. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
When Rabium Plus Capsule 10's and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Rabium Plus Capsule 10's.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleAtazanavir
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Rabium Plus Capsule 10's, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Taking Rabium Plus Capsule 10's together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Taking Rabium Plus Capsule 10's together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleDasatinib
Severe
How does the drug interact with Rabium Plus Capsule 10's:
Taking Rabium Plus Capsule 10's together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Rabium Plus Capsule 10's and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Rabium Plus Capsule Substitute

Substitutes safety advice
  • Veloz IT Capsule 10's

    27.90per tablet
  • Rablet IT Capsule 10's

    29.34per tablet
  • Razocid-IT Capsule 10's

    20.61per tablet
  • Cyra IT Capsule 10's

    14.40per tablet
  • Razo-IT 20 mg/150 mg Capsule 10's

    22.77per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Rabium Plus Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Rabium Plus Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Rabium Plus Capsule ; your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Rabium Plus Capsule causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Rabium Plus Capsule if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Rabium Plus Capsule if you have kidney impairment or any concerns.

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Children

Unsafe

Rabium Plus Capsule should not be given to children as safety and effectiveness were not established.

FAQs

Rabium Plus Capsule is used to treat GERD (gastro-oesophagal reflux disease), and peptic ulcers.
Rabium Plus Capsule is a combination of two drugs: Â Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI), that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting. Â It increases gastric emptying, and improves gastric sensitivity and tension by increasing the movement of the stomach, and intestines in the upper digestive tract. It also has anti-emetic action. Together, Rabium Plus Capsule helps prevent acid reflux and provide relief from acidity.
Talk to your doctor if you do not feel better even after taking Rabium Plus Capsule for 14 days. Do not take Rabium Plus Capsule for longer durations unless prescribed by the doctor.
Diarrhoea might be a side-effect of Rabium Plus Capsule . Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid or limit the consumption of alcohol while taking Rabium Plus Capsule as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Rabium Plus Capsule contains lactose monohydrate, so a person who is intolerant to sugar should tell their doctor before taking this medicine.
Consult your doctor before taking Rabium Plus Capsule if you are pregnant or planning for pregnancy. Your doctor will prescribe Rabium Plus Capsule only if the benefits outweigh the risks.
The common side effects of Rabium Plus Capsule include headache, nausea, stomach pain, dizziness, and diarrhoea. If these side effects persist or worsen, please consult your doctor.
Take Rabium Plus Capsule at the time recommended by your doctor. It is usually best to take it 30 to 60 minutes before breakfast, as this helps the medication work effectively to reduce stomach acid.
Rabium Plus Capsule is contraindicated in people who are allergic to any of its components. Inform your doctor before taking Rabium Plus Capsule if you have a history of gastrointestinal bleeding, mechanical perforation or obstruction, or a movement disorder. Do not take Rabium Plus Capsule if you are pregnant or breastfeeding unless prescribed by a doctor.
Rabium Plus Capsule may cause dizziness as a side effect. If you feel dizzy after taking Rabium Plus Capsule , avoid driving or using machinery until you feel alert again. If the dizziness continues, please contact your doctor.
Rabium Plus Capsule contains rabeprazole (a proton pump inhibitor), which may increase the risk of fractures, particularly of the hip, wrist, and spine, when used long-term or in multiple daily doses, especially in older adults. This is primarily due to reduced calcium absorption. If you are using Rabium Plus Capsule for an extended period, monitor your bone health regularly (e.g., calcium levels, bone density) and talk to your doctor if you have any concerns.
Rabium Plus Capsule is not usually known to affect your ability to drive. However, if you experience side effects like dizziness or drowsiness after taking Rabium Plus Capsule , it is best to avoid driving.
Rabium Plus Capsule should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - RAB0037

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