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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Qdine 200mg Tablet is used to treat malaria. It gives a degree of protection against malaria when people travel to areas where malaria cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. It is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). It contains Chloroquine, which kills the organisms causing malaria and amoebiasis. It may cause common side effects such as vomiting, nausea, hair loss and itchy skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CHLOROQUINE-200MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Qdine 200mg Tablet

Qdine 200mg Tablet belongs to the class of medications called 'quinoline' primarily used to treat malaria. Qdine 200mg Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Qdine 200mg Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Qdine 200mg Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Qdine 200mg Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Qdine 200mg Tablet should be taken as prescribed by your doctor. The dose of Qdine 200mg Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Qdine 200mg Tablet include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Qdine 200mg Tablet, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Qdine 200mg Tablet on your own. Qdine 200mg Tablet is safe to use during pregnancy and breastfeeding. Prolonged use of Qdine 200mg Tablet may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Qdine 200mg Tablet

Treatment of Malaria, Intestinal amoebiasis, Rheumatoid arthritis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Qdine 200mg Tablet falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Qdine 200mg Tablet contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Qdine 200mg Tablet is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

How Qdine 200mg Tablet Works

Qdine 200mg Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Qdine 200mg Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Qdine 200mg Tablet

  • Abnormal heart rhythm
  • Stomach pain
  • Nausea (being sick)
  • Diarrhoea
  • Loss of appetite
  • Headache
  • Skin rash
  • Liver problems

What if I have taken an overdose of Qdine 200mg Tablet

Do not take more than the prescribed dose of Qdine 200mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Qdine 200mg Tablet does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Qdine 200mg Tablet. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Qdine 200mg Tablet cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Drug-Drug Interactions

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ChloroquineAgalsidase beta
Critical
ChloroquineThioridazine
Critical

Drug-Drug Interactions

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ChloroquineAgalsidase beta
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Qdine 200mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineThioridazine
Critical
How does the drug interact with Qdine 200mg Tablet:
When Thioridazine and Qdine 200mg Tablet are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineCisapride
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking Qdine 200mg Tablet with Cisapride can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineBepridil
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineAgalsidase alfa
Critical
How does the drug interact with Qdine 200mg Tablet:
When Agalsidase alfa is used with Qdine 200mg Tablet, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Qdine 200mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineAurothioglucose
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking Aurothioglucose with Qdine 200mg Tablet can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Qdine 200mg Tablet is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineDronedarone
Critical
How does the drug interact with Qdine 200mg Tablet:
When Qdine 200mg Tablet is taken with Dronedarone, it may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Dronedarone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquinePimozide
Critical
How does the drug interact with Qdine 200mg Tablet:
When Pimozide and Qdine 200mg Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Pimozide is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineSparfloxacin
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet together with sparfloxacin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Sparfloxacin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineZiprasidone
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking Qdine 200mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit products while using Qdine 200mg Tablet, can increase the risk of irregular heartbeat, which may result in side effects such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Avoid grape fruit and its products while taking Qdine 200mg Tablet.

Diet & Lifestyle Advise

  • Always take Qdine 200mg Tablet with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Qdine 200mg Tablet Substitute

Substitutes safety advice
  • Chloromax D Tablet 10's

    14.40per tablet
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Alcohol

Caution

No serious interaction has been reported between alcohol and Qdine 200mg Tablet yet alcohol should be avoided with Qdine 200mg Tablet as it aggravates side effects.

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Pregnancy

Caution

Qdine 200mg Tablet should be used with caution and can only be used in pregnancy if recommended by the doctor.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Qdine 200mg Tablet as this medicine can pass into breast milk. A patient is advised to take this drug only on doctor's consultation.

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Driving

Caution

Qdine 200mg Tablet may cause blurred vision, so one should avoid driving or doing any activity that needs mental alertness. A patient is thus advised to take this drug only on doctor's consultation.

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Liver

Caution

Qdine 200mg Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Qdine 200mg Tablet.

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Kidney

Caution

Qdine 200mg Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Qdine 200mg Tablet.

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Children

Safe if prescribed

Qdine 200mg Tablet is safe to use in children, yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.

FAQs

Qdine 200mg Tablet is used to treat malaria. Qdine 200mg Tablet gives a degree of protection against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Qdine 200mg Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
Qdine 200mg Tablet works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.
The use of Qdine 200mg Tablet is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.
No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.
No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking Qdine 200mg Tablet is advised to consult a doctor and have regular check-ups cyclically.
There may be a risk of hemolysis in patients with G6PD deficiency while using Qdine 200mg Tablet. Doctor's consultation is mandatory before you start this medication.

Country of origin

India
Other Info - QD42346

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