Pyrimethamine 25 mg Tablet is an antimalarial medicine used in the treatment of malaria. Malaria is a parasitic disease caused by the plasmodium species. The infection occurs when the mosquito bites and enters the human body. Symptoms may include chills, on-and-off fever, and sweating. This medicine is only used to treat the infection. It is not recommended to prevent or treat severe conditions (where the infection is spread to the brain, kidneys, or lungs). Pyrimethamine 25 mg Tablet is also used in the treatment of toxoplasmosis (infection caused by parasites toxoplasma gondii) and also in chemoprophylaxis of malaria.

Pyrimethamine 25 mg Tablet contains Pyrimethamine, which belongs to the class of antimalarial/antiparasitic drugs. It works by increasing the harmful, toxic and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading. In this way, Pyrimethamine 25 mg Tablet is used for the prevention of relapse of malaria caused by parasites.

Pyrimethamine 25 mg Tablet may cause certain side effects such as nausea, dizziness, vomiting, headache, diarrhoea, body pain, stomach discomfort, and injection site reactions. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor immediately. Pyrimethamine 25 mg Tablet should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on the severity of your disease. Always take the medicine on time without skipping any dose.

Pyrimethamine 25 mg Tablet should be avoided if you are allergic to it or any other artemisinin derivatives. It is contraindicated in patients with megaloblastic anemia. Inform your doctor if you have/had any conditions such as anemia,  liver/kidney disease, heart problem, or taking any other medicines before taking Pyrimethamine 25 mg Tablet as it may cause serious side effects under these conditions. If you are pregnant or breastfeeding, inform your doctor before taking Pyrimethamine 25 mg Tablet . This medicine is used in combination with other medicines for the treatment of malaria. 

Pyrimethamine 25 mg Tablet contains Pyrimethamine, which belongs to the class of antimalarial/ antiparasitic drugs. It works by increasing the harmful, toxic and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading. In this way, Pyrimethamine 25 mg Tablet is used for the prevention of relapse of malaria caused by plasmodium species. Pyrimethamine 25 mg Tablet is in combination with other antimalarial medicines such as chloroquine or quinine for the treatment of malarial infection.

• Vomiting
• Headache
• Stomach pain
• Dizziness
• Lightheadedness
• Abdominal pain
• Weakness
• Nausea

Avoid using Pyrimethamine 25 mg Tablet if you are allergic to it or any other artemisinin derivatives. Inform your doctor if you have/had any conditions such as liver/kidney disease, heart problem, or taking any other medicines before receiving Pyrimethamine 25 mg Tablet as it may cause serious side effects under these conditions. Pyrimethamine 25 mg Tablet is recommended for use in children only if prescribed by the paediatrician, and if administered, proper care and dosing should be checked. This medicine is used alone or in combination with other medicines for the treatment of malaria.

Drug-Drug Interactions: Pyrimethamine 25 mg Tablet may interact with antacids and many other medicines. Hence, inform your doctor on priority.

Drug-Food Interactions: No interactions found. 

Drug-Disease Interactions: Pyrimethamine 25 mg Tablet should be used with caution in patients with severe liver and kidney failure, gastrointestinal system (gut), and heart problems.

• It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
• Try to add protein to your diet for malaria-induced weight loss.
• Eating at the right time and taking proper rest is important for the patient to recover.
• Avoid eating fried and processed foods, and junk oily and spicy foods can aggravate nausea and disturb the body's digestion process.
• Eat nutritious food that helps to improve malaria-induced weakness
• Keep your area and surroundings mosquito-free.
• Use mosquito-repellent products to avoid the recurrence of infections and any other further complications.

Malaria: It is a life-threatening parasitic disease caused by mosquito bites. When the mosquito bites, the plasmodium parasite enters the body multiplies in the liver, spreads via the bloodstream, and thus causes the infection by releasing toxic chemicals. Four types of plasmodium parasites can infect humans with malaria such as Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Symptoms may include chills, on-and-off fever, sweating, vomiting, etc.

Toxoplasmosis: It is an infection caused by parasites toxoplasma gondii found in contaminated food and cat faeces. It can cause serious complications for pregnant women, such as miscarriage, stillbirths, and damage to the baby’s brain and other organs, particularly the eyes, at birth or early childhood, and people with weakened immune systems. Symptoms include muscle pain, fever, headache, etc.