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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Pymet 5mg/500mg Tablet is used to treat signs of migraine such as headache, vomiting, and nausea. It contains two medicines, namely Metoclopromide and Paracetamol, which help prevent nausea and vomiting and relieve pain. It may cause common side effects such as dizziness, sleepiness, diarrhoea, irregular periods, weakness, nervousness and breast enlargement in men.

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Manufacturer/Marketer :

Suzikem Drugs Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pymet 5mg/500mg Tablet

Pymet 5mg/500mg Tablet is used to treat signs of migraine such as headache, being sick (vomiting), and feeling sick (nausea). Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which generally occurs on one side of the head; however, it can occur on both sides or shift.

Pymet 5mg/500mg Tablet is a combination of two drugs: Metoclopramide (anti-emetics) and Paracetamol (analgesics). Metoclopramide works on the part of the brain and prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, which helps empty the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins, which cause pain. Together, Pymet 5mg/500mg Tablet helps relieve the symptoms of migraine.

Take Pymet 5mg/500mg Tablet as prescribed. You are advised to take Pymet 5mg/500mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, sleepiness, diarrhoea, irregular periods, weakness, nervousness and breast enlargement in men. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Pymet 5mg/500mg Tablet if you are pregnant or breastfeeding. Pymet 5mg/500mg Tablet should not be taken during the first 6 months of pregnancy. Pymet 5mg/500mg Tablet may cause drowsiness and sleepiness, so drive with caution. Pymet 5mg/500mg Tablet is not recommended for children below 18 years as safety and efficacy have not been established. Avoid consuming alcohol with Pymet 5mg/500mg Tablet as it could lead to increased drowsiness and sleepiness. Inform your doctor about your health condition and medicines you are taking to rule out unpleasant side effects.

Uses of Pymet 5mg/500mg Tablet

Pymet 5mg/500mg Tablet is used to treat migraines.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Pymet 5mg/500mg Tablet is a combination of two drugs: Metoclopramide and Paracetamol. Pymet 5mg/500mg Tablet is used to treat migraine signs such as headache, being sick (vomiting) and feeling sick (nausea). Metoclopramide is an anti-emetic that works on the part of the brain, thereby preventing the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, which helps empty the stomach. Paracetamol is an analgesic that works by blocking the effect of a chemical messenger known as prostaglandins, which cause pain. Thereby, helps in relieving pain. Together, Pymet 5mg/500mg Tablet helps relieve the symptoms of migraines such as headache, nausea, and vomiting.

How Pymet 5mg/500mg Tablet Works

Pymet 5mg/500mg Tablet is a combination of two drugs: Metoclopramide (anti-emetics) and Paracetamol (analgesics). Metoclopramide works on the part of the brain and prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, which helps empty the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins, which cause pain. Together, Pymet 5mg/500mg Tablet helps relieve the symptoms of migraine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pymet 5mg/500mg Tablet

  • Dizziness
  • Sleepiness
  • Diarrhoea
  • Irregular periods
  • Weakness
  • Nervousness
  • Breast enlargement in men

What if I have taken an overdose of Pymet 5mg/500mg Tablet

Do not take more than the prescribed dose of Pymet 5mg/500mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pymet 5mg/500mg Tablet if you are allergic to any of its contents; if you have/had a blockage or bleeding in your stomach, epilepsy/fits, phaeochromocytoma (tumour of the adrenal gland), uncontrollable movements of the face, arms or legs after taking metoclopramide or medicines used to calm mental problems, if you had an operation on stomach or intestine or if you are taking levodopa. Inform your doctor before taking Pymet 5mg/500mg Tablet if you have/had severe kidney or liver problems; if you are 65 years or older. Consult your doctor if you are pregnant or breastfeeding. Pymet 5mg/500mg Tablet should not be taken during the first six months of pregnancy.  Pymet 5mg/500mg Tablet may cause sleepiness and dizziness, so drive only if you are alert. Pymet 5mg/500mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol with Pymet 5mg/500mg Tablet as it could lead to increased sleepiness. Pymet 5mg/500mg Tablet contains paracetamol; do not take any other medicines containing paracetamol along with Pymet 5mg/500mg Tablet unless prescribed.

Drug-Drug Interactions

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MetoclopramideVenlafaxine
Critical
MetoclopramideAmisulpride
Critical

Drug-Drug Interactions

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MetoclopramideVenlafaxine
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideAmisulpride
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Taking Pymet 5mg/500mg Tablet with Amisulpride may increase the risk or severity of side effects.

How to manage the interaction:
Taking Amisulpride with Pymet 5mg/500mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
MetoclopramideParoxetine
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Using Pymet 5mg/500mg Tablet with Paroxetine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Paroxetine is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramidePromethazine
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Pymet 5mg/500mg Tablet is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideRisperidone
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Risperidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Risperidone with Pymet 5mg/500mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
MetoclopramideAripiprazole
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Pymet 5mg/500mg Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramidePimozide
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with Pimozide can increase the risk of negative side effects.

How to manage the interaction:
Taking Pimozide with Pymet 5mg/500mg Tablet is not recommended, as it can possibly lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience muscle pain or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramideQuetiapine
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Coadministration of Pymet 5mg/500mg Tablet with quetiapine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Quetiapine is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideBupropion
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Bupropion can increase the levels of Pymet 5mg/500mg Tablet and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Pymet 5mg/500mg Tablet with Bupropion is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideCariprazine
Critical
How does the drug interact with Pymet 5mg/500mg Tablet:
Co-administration of Pymet 5mg/500mg Tablet with Cariprazine can increase the risk of side effects.

How to manage the interaction:
Taking Cariprazine with Pymet 5mg/500mg Tablet is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Pymet 5mg/500mg Tablet Substitute

Substitutes safety advice
  • Metopar Tablet 15's

    2.94per tablet
  • Paramet Tablet 10's

    3.11per tablet
  • Metamol 5mg/500mg Tablet

    1.31per tablet
  • Migrosh 5mg/500mg Tablet

    0.81per tablet
  • Fenomet 5 mg/500 mg Tablet

    0.85per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pymet 5mg/500mg Tablet as it may cause increased sleepiness.

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Pregnancy

Unsafe

Pymet 5mg/500mg Tablet should not be taken during the first 6 months of pregnancy. Please consult your doctor before taking Pymet 5mg/500mg Tablet if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Pymet 5mg/500mg Tablet may pass into breastmilk. Please consult your doctor before taking Pymet 5mg/500mg Tablet if you are breastfeeding.

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Driving

Caution

Pymet 5mg/500mg Tablet may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Use Pymet 5mg/500mg Tablet in children only if prescribed by a doctor.

FAQs

Pymet 5mg/500mg Tablet is used to treat signs of migraine such as headache, being sick (vomiting), and feeling sick (nausea).
Pymet 5mg/500mg Tablet contains Metoclopramide and Paracetamol. Metoclopramide works on the part of the brain, thereby prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, this helps in emptying the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins which cause pain. Thereby, helps in relieving pain.
Consult your doctor before taking oral contraceptive pills along with Pymet 5mg/500mg Tablet as they might decrease the effectiveness of Pymet 5mg/500mg Tablet. Talk to your doctor, he/she may advise you to use an alternate method of contraception.
Pymet 5mg/500mg Tablet contains Paracetamol, an analgesic used to provide relief from pain. Therefore, please consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Pymet 5mg/500mg Tablet as they may also contain paracetamol.
If you had an operation on your stomach or intestine, do not take Pymet 5mg/500mg Tablet during the first 3-4days after the surgery. However, please talk to your doctor before taking Pymet 5mg/500mg Tablet if you have had surgery.
Diarrhoea could be a side-effect of Pymet 5mg/500mg Tablet. Drink plenty of liquids to replace the lost fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Pymet 5mg/500mg Tablet may cause irregular periods or loss of periods. Please consult your doctor if you experience this for longer than a few days.
Pymet 5mg/500mg Tablet contains metoclopramide, which can cause side effects like drowsiness and dizziness. Therefore, avoid giving Pymet 5mg/500mg Tablet before a task that requires mental focus such as running, jogging or cycling, or any other sports activity.
Pymet 5mg/500mg Tablet can enter the brain and can cause serious side effects including unusual mood changes such as anxiety, depression or agitation and uncontrolled and repeated movements of the arms, legs, eyes, mouth, tongue, face and jaw. If you experience any of these side effects, stop taking Pymet 5mg/500mg Tablet and consult your doctor immediately.
Pymet 5mg/500mg Tablet is not recommended for use in patients who are allergic to Pymet 5mg/500mg Tablet, who have stomach or digestive tract bleeding, intestinal blockage, recent stomach or intestine surgery, phaeochromocytoma (a rare tumour of the adrenal gland) or epilepsy.
Children who are malnourished, who are suffering from liver/kidney disease, heart disease, electrolyte disturbances, antipsychotic medications, or atopic allergies, should consult your doctor before taking Pymet 5mg/500mg Tablet.
Overdose of Pymet 5mg/500mg Tablet may make your child feel dizzy, sleepy or drowsy, confused, sweaty, vomit, have pain in the stomach, have convulsions or fits, or experience uncontrolled muscle movements or notice yellowing of the skin. If you notice these symptoms, please consult your doctor immediately.
Store Pymet 5mg/500mg Tablet at temperature not exceeding 25°C, protect from sunlight. Keep out of reach of children.
You are recommended to consult your doctor before taking other medicines with Pymet 5mg/500mg Tablet to avoid possible interactions.
The common side effects of Pymet 5mg/500mg Tablet are dizziness, restlessness, fatigue, drowsiness, diarrhoea, and weakness. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - PY60334

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