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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 11, 2024 | 2:35 PM IST
Puzint 500 Tab is used for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age. It contains Cefuroxime, which kills a wide range of bacteria. It may cause common side effects like headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CEFUROXIME-500MG

Manufacturer/Marketer :

Pranyog Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Puzint 500 Tab

Puzint 500 Tab belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

Puzint 500 Tab is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take Puzint 500 Tab only if your doctor has prescribed you. Puzint 500 Tab is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with Puzint 500 Tab, you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of Puzint 500 Tab can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a Puzint 500 Tab effect on the mother or baby during pregnancy. However, one should take the Puzint 500 Tab with caution. Puzint 500 Tab is excreted in the breastmilk, so the nursing mother should cautiously take Puzint 500 Tab. This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. Puzint 500 Tab is not recommended for people allergic or hypersensitive to Puzint 500 Tab, penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with Puzint 500 Tab. Liver and kidney-affected people should take this medication with caution.

Uses of Puzint 500 Tab

Treatment of Bacterial infections

Medicinal Benefits

Puzint 500 Tab treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Puzint 500 Tab also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of Puzint 500 Tab is seven days (5-10 days). But, your doctor might prescribe you Puzint 500 Tab for a longer duration depending on the condition of infection. Puzint 500 Tab has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

Side Effects of Puzint 500 Tab

  • Headache

  • Dizziness
  • Stomach upset
  • Overgrowth of candida (fungal skin infection)
  • Unpleasant taste in the mouth
  • Diaper rashes
  • Eosinophilia (increased disease-fighting cells/WBC) 

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Special care should be taken by the people taking Puzint 500 Tab who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of Puzint 500 Tab may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping Puzint 500 Tab. The case of colitis (inflammatory bowel disease) has been reported using Puzint 500 Tab. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking Puzint 500 Tab. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of Puzint 500 Tab immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking Puzint 500 Tab for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking Puzint 500 Tab should be warned to be cautious when driving or operating machinery.

Therapeutic Class

ANTI- BACTERIALS

Drug-Drug Interactions

verifiedApollotooltip
CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
CEFUROXIME-500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-500MGChronic kidney disease
Moderate

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Puzint 500 Tab to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Puzint 500 Tab.

  • Avoid intake of alcoholic beverages with Puzint 500 Tab as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Puzint 500 Tab in fighting off infections.

Habit Forming

No

What if I have taken an overdose of Puzint 500 Tab

Do not take more than the prescribed dose of Puzint 500 Tab as it may cause overdose. The symptoms of overdose include seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Puzint 500 Tab.

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Pregnancy

Safe if prescribed

Puzint 500 Tab is a pregnancy category B drug. So, Puzint 500 Tab can be safely taken by pregnant women if prescribed by the doctor.

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Breast Feeding

Safe if prescribed

Puzint 500 Tab is excreted in human milk, caution should be exercised. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

No studies on the effects on the ability to drive and use machines have been performed. However, as this medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.

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Liver

Caution

Consult your doctor, there is no substantial research yet on the use of Puzint 500 Tab

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Kidney

Caution

Consult your doctor, there is no substantial research yet on the use of Puzint 500 Tab

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Children

Safe if prescribed

Puzint 500 Tab can be given safely to children provided dose has been prescribed by a child specialist. However, There is no clinical evidences of using Puzint 500 Tab in children under the age of 3 months.

Country of origin

India

Manufacturer/Marketer address

G-33 G/F Plot No. 218 Vardhman Mayur Market Csc Mayur Vihar-Iii Vashundra Delhi East Delhi Dl 110096 In
Other Info - PUZ0001

Author Details

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FAQs

Puzint 500 Tab is used to treat a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect).
Puzint 500 Tab is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
You should avoid taking Puzint 500 Tab with oral birth control pills, medicines that reduces gastric acidity (like antacids, omeprazole), immuno suppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with thyphoid and BCG vaccines.
Depending upon the severity of your medical condition your doctor may prescribe it to you daily for a specific duration. The usual dose ofPuzint 500 Tab is 7 days (5-10 days), but depending on your current infection state your doctor may extend your dose intake for more days.
Try to stay well hydrated by drinking at least 6 glass of water or other fluid per day. Keep your underwear clean and try to use underwear made of cotton to avoid the spread of infection. Always keep your bladder empty as much possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat urinary tract infection.
After taking an antibiotic you may need to wait for up to three hours for eating or drinking any dairy products include milk as well as butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work dampen the effect of antibiotics.
If you have taken accidently over dosage of Puzint 500 Tab, you may have diarrhoea, nausea or vomiting. In rare cases it can also cause convulsion or seizures (fits). Try to reach out to doctor in this case.
No. Puzint 500 Tab treats only bacterial infection. Cough, flu or cold are usually caused due to the viruses. So, you should consult doctor for these conditions.
Yes. Puzint 500 Tab may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if your are using any birth control pills.
No. You should complete the full course of Puzint 500 Tab as your doctor prescribes. After completing the full course, the Puzint 500 Tab will work. You must take Puzint 500 Tab at the right dose, times, and for the right number of days.
Puzint 500 Tab might be a safer alternative if you are allergic to amoxicillin. However, please consult the doctor before starting Puzint 500 Tab.
Puzint 500 Tab helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections.
Puzint 500 Tab may cause dizziness in some cases. Therefore, drive or operate machinery only if you are alert.
Do not discontinue Puzint 500 Tab without consulting the doctor. To treat your infection effectively, continue taking Puzint 500 Tab for the prescribed duration even though you feel better.
If you miss a dose of Puzint 500 Tab take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Puzint 500 Tab may interact with other medications. Consult the doctor if you are taking oral birth control pills, antacids, immuno-suppressing drugs, or medicines used for reducing uric acid.
Avoid alcohol consumption as it might lower the effectiveness of Puzint 500 Tab.
Puzint 500 Tab can be taken by pregnant or breastfeeding women if prescribed by the doctor. Please consult the doctor if you are pregnant, think you are pregnant, planning for pregnancy or breastfeeding.
Side effects of Puzint 500 Tab include headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), and an unpleasant taste in the mouth. Consult the doctor if the side effects persist or worsen.

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