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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Pustulex Gel is used to treat acne. It contains Dapsone which works by inhibiting the growth of acne-causing bacteria. In some cases, this medicine may cause side effects such as skin peeling, dry skin, itching, and redness. Before using this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

DAPSONE-5%W/W

Manufacturer/Marketer

Amwill Healthcare Pvt Ltd

Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pustulex Gel

Pustulex Gel belongs to the class of antibiotics used to treat acne (pimples). Acne is a skin condition that is common and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin), causing redness and swelling.

Pustulex Gel contains Dapsone (antibiotic) that works by inhibiting the production of folic acid (vitamin) necessary for bacteria to grow, multiply and increase in numbers. Thereby stops or slows down the growth of bacteria and clears acne.

Use Pustulex Gel as prescribed by your doctor. You are advised to use Pustulex Gel for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience bluish tinge to the skin, skin peeling, dry skin, itching, redness or oiliness of the skin. Most of these side effects of Pustulex Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dapsone or any other medicines, please tell your doctor. You are recommended to consult a doctor if you are breastfeeding or pregnant. If you get shortness of breath, weakness, back pain, tiredness, dark brown urine, fever, pale or yellow skin, stop using Pustulex Gel and consult a doctor immediately as they might be symptoms of haemolytic anaemia (breakdown of red blood cells).

Uses of Pustulex Gel

Treatment of Acne

Medicinal Benefits

Pustulex Gel contains Dapsone used to treat acne (pimples). Pustulex Gel inhibits the production of folic acid (vitamin) necessary for bacteria to grow, multiply and increase in numbers. Thereby, it stops or slows down the growth of bacteria causing acne and heals the skin by reducing swelling and redness. 

Directions for Use

Wash your hands before and after applying Pustulex Gel. Apply a small amount of gel as a thin layer and gently rub on the clean and dry affected area of the skin as advised by your doctor. It is only for external use. Avoid contact of gel with mouth, eyes or vagina as it may cause irritation. In case it comes in contact with these areas accidentally, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pustulex Gel

  • Bluish tinge to the skin
  • Skin peeling
  • Dry skin
  • Itching, redness or oiliness of the skin

Drug Warnings

If you are allergic to Dapsone or any other medicines, please tell your doctor. If you have methemoglobinemia (high levels of methemoglobin in blood), inform your doctor before using Pustulex Gel. Avoid contact of topical form with mouth, eyes or vagina. In case it comes in contact with these areas accidentally, rinse with water thoroughly. You are recommended to consult a doctor if you are breastfeeding or pregnant. Do not apply the gel in large amounts or use it for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. If you get shortness of breath, weakness, back pain, tiredness, dark brown urine, fever, pale or yellow skin, stop using Pustulex Gel and consult a doctor immediately as they might be symptoms of haemolytic anaemia (breakdown of red blood cells). This condition usually occurs in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency using Pustulex Gel.

Drug Interactions

Drug-Drug Interaction: Pustulex Gel may interact with keratolytic agents (benzoyl peroxide). Therefore, inform your doctor if you are using any other prescription, non-prescription or herbal medicines.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have glucose 6-phosphate dehydrogenase (G6PD) deficiency or methemoglobinemia (blood disorder), please inform your doctor before using Pustulex Gel. 

Drug-Drug Interactions Checker List

  • BENZOYL PEROXIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Do regular hair wash regularly and avoid hair falling across the face.
  • Remove the makeup completely before going to bed.
  • Avoid using products that may cause skin irritation, such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents and rough fabrics.

Special Advise

If your skin condition does not improve after using Pustulex Gel for 12 weeks, please consult a dermatologist so that alternative treatments for acne may be prescribed.

Disease/Condition Glossary

Acne: It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, red, large and tender bumps. The treatment for acne includes certain creams, cleansers and antibiotics.

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Alcohol

Consult your doctor

Interaction of Pustulex Gel with alcohol is unknown. Please consult a doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant. Pustulex Gel is given to pregnant women if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult a doctor if you are breastfeeding. Pustulex Gel is given to breastfeeding women if the doctor thinks the benefits are greater than the risks.

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Driving

Safe if prescribed

Pustulex Gel usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Pustulex Gel in patients with liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Pustulex Gel in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Pustulex Gel is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

No.157, 1St Floor, 2Nd Main Road, 3Rd Cross, Chamrajpet, Bangalore, Karnataka 560018 €“ India
Other Info - PUS0015

Author Details

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FAQs

Pustulex Gel is used to treat acne (pimples).
Pustulex Gel contains Dapsone. Pustulex Gel is an antibiotic that works by inhibiting the production of folic acid (vitamin) that is necessary for bacteria to grow, multiply and increase in numbers. Thereby stops or slows down the growth of bacteria and clears acne.
You are not recommended to use benzoyl peroxide with Pustulex Gel at the same time as it may cause temporary orange or yellow discolouration of facial hair or skin. However, please consult a doctor before using other products with the topical form.
Pustulex Gel may cause methemoglobinemia (a serious condition that occurs when oxygen amount in the blood decreases severely) as a side effect. It is not necessary for everyone using Pustulex Gel to experience this side effect. However, if you notice a grey or blue appearance of your fingernails, lips or inside of your mouth, stop using Pustulex Gel and consult a doctor immediately.
You are recommended to use Pustulex Gel for as long as your doctor has prescribed it. However, if the condition persists or worsens after using Pustulex Gel for 12 weeks, please consult a doctor.
Pustulex Gel may cause dryness of the skin. You can use a moisturizer while using Pustulex Gel to prevent dry skin. However, do not apply Pustulex Gel and moisturizer at the same time as it may reduce the effectiveness of Pustulex Gel. Please consult a doctor before using other products with Pustulex Gel.
Pustulex Gel is not an immunosuppressant or a steroid. It is an antibiotic used to treat acne.
Pustulex Gel should be used during pregnancy and lactation only if advised by the doctor. You are recommended to consult a doctor if you are breastfeeding or pregnant.
There was no evidence of clinically relevant anaemia in patients treated with Pustulex Gel due to low systemic absorption. However, patients with glucose‐6‐phosphate dehydrogenase deficiency or a history of methemoglobinemia are more susceptible to drug‐induced methemoglobinemia (a blood disorder in which an abnormal amount of methemoglobin). Consult the doctor if you notice bluish colouration of skin, lips and nail beds.
Inform your doctor if you are using keratolytic agents (benzoyl peroxide) or any other prescription, non-prescription or herbal medicines.
Clean and dry the affected area. Apply a small amount of Pustulex Gel as a thin layer and gently rub on the affected area of the skin as advised by your doctor.
Pustulex Gel stops or slows down the growth of acne-causing bacteria and heals the skin by reducing swelling and redness.
Pustulex Gel is only for external use; do not swallow it. Avoid contact of Pustulex Gel with mouth, eyes or vagina as it may cause irritation. In case it comes in contact with these areas accidentally, rinse with water thoroughly.
Apply the missed dose as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and use the next dose at the scheduled time.
Pustulex Gel may cause side effects like bluish tinge to the skin, skin peeling, dry skin, itching, redness or oiliness of the skin. Most of these side effects of Pustulex Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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