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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Puricor 50 mg Tablet is used to treat blood cancer. It contains Mercaptopurine that works by inhibiting the growth, repair and multiplication of cancer cells. This medicine may sometimes cause side effects such as vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

MERCAPTOPURINE-50MG

Manufacturer/Marketer :

Vhb Life Sciences Inc

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Puricor 50 mg Tablet

Puricor 50 mg Tablet belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

Puricor 50 mg Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take Puricor 50 mg Tablet as prescribed by your doctor. You are advised to take Puricor 50 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of Puricor 50 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Puricor 50 mg Tablet or any other medicines, please tell your doctor. Avoid taking Puricor 50 mg Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Puricor 50 mg Tablet and for 3 months after completing the course of Puricor 50 mg Tablet to prevent pregnancy. Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as Puricor 50 mg Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Puricor 50 mg Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

Uses of Puricor 50 mg Tablet

Treatment of Blood cancer (Acute lymphoblastic leukaemia)

Directions for Use

Take Puricor 50 mg Tablet with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Puricor 50 mg Tablet contains Mercaptopurine, an anticancer drug used to treat blood cancer. Puricor 50 mg Tablet interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells. 

How Puricor 50 mg Tablet Works

Puricor 50 mg Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Puricor 50 mg Tablet

  • Nausea
  • Vomiting
  • Low red blood cell count
  • Loss of appetite
  • Diarrhoea
  • Inflammation of the mouth

What if I have taken an overdose of Puricor 50 mg Tablet

Take Puricor 50 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include loss of appetite, nausea, vomiting, diarrhoea, pale skin, weakness, shortness of breath, signs of infection (sore throat, fever, chills), and unusual bruising or bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Puricor 50 mg Tablet or any other medicines, please tell your doctor. Avoid taking Puricor 50 mg Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Puricor 50 mg Tablet and 3 months after completing the course of Puricor 50 mg Tablet to prevent pregnancy. Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Puricor 50 mg Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as Puricor 50 mg Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Puricor 50 mg Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking Puricor 50 mg Tablet to cause infections. 

Drug-Drug Interactions

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MercaptopurineBCG vaccine
Critical
MercaptopurineFebuxostat
Critical

Drug-Drug Interactions

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MercaptopurineBCG vaccine
Critical
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of the BCG vaccine with Puricor 50 mg Tablet 10's together can increase the risk of infection.

How to manage the interaction:
Taking Puricor 50 mg Tablet 10's with BCG vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineFebuxostat
Critical
How does the drug interact with Puricor 50 mg Tablet 10's:
Coadministration of Puricor 50 mg Tablet 10's with Febuxostat can increase the blood levels of Puricor 50 mg Tablet 10's.

How to manage the interaction:
Taking Puricor 50 mg Tablet 10's with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
MercaptopurineYellow fever vaccine
Critical
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of the Yellow fever vaccine with Puricor 50 mg Tablet 10's can increase the risk of infection.

How to manage the interaction:
Taking Puricor 50 mg Tablet 10's with the Yellow fever vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineTalimogene laherparepvec
Critical
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of Talimogene laherparepvec with Puricor 50 mg Tablet 10's can increase the risk or severity of side effects.

How to manage the interaction:
Taking Puricor 50 mg Tablet 10's with Talimogene laherparepvec is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineRotavirus vaccine
Critical
How does the drug interact with Puricor 50 mg Tablet 10's:
When Rotavirus vaccine is used together with Puricor 50 mg Tablet 10's, its effectiveness may be reduced.

How to manage the interaction:
Taking Puricor 50 mg Tablet 10's with the Rotavirus vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineDeferiprone
Severe
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of Deferiprone and Puricor 50 mg Tablet 10's together can increase the risk of neutropenia.

How to manage the interaction:
Although taking Puricor 50 mg Tablet 10's and Deferiprone together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor immediately, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination. Do not discontinue any medications without consulting a doctor.
MercaptopurineFingolimod
Severe
How does the drug interact with Puricor 50 mg Tablet 10's:
Taking Fingolimod and Puricor 50 mg Tablet 10's may increase the risk of severe infections.

How to manage the interaction:
Although there is a possible interaction between Puricor 50 mg Tablet 10's and Fingolimod, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
MercaptopurineCladribine
Severe
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of Cladribine with Puricor 50 mg Tablet 10's together can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Puricor 50 mg Tablet 10's, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
MercaptopurineCertolizumab
Severe
How does the drug interact with Puricor 50 mg Tablet 10's:
Co-administration of Puricor 50 mg Tablet 10's with Certolizumab can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Puricor 50 mg Tablet 10's and Certolizumab, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact your doctor immediately - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning when you pee. Do not stop using any medications without a doctor's advice.
MercaptopurineTofacitinib
Severe
How does the drug interact with Puricor 50 mg Tablet 10's:
Taking Tofacitinib and Puricor 50 mg Tablet 10's increases the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Puricor 50 mg Tablet 10's and Tofacitinib, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Puricor 50 mg Tablet as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Puricor 50 mg Tablet Substitute

Substitutes safety advice
  • 6-MP Tablet 10's

    5.56per tablet
  • Admerk 50 mg Tablet 10's

    5.91per tablet
  • Merinethol 50 mg Tablet 10's

    5.22per tablet
  • Captomer 50mg Tablet

    4.50per tablet
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Alcohol

Caution

Interaction of Puricor 50 mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Puricor 50 mg Tablet .

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Pregnancy

Unsafe

Puricor 50 mg Tablet is a category D pregnancy drug and is not recommended for use during pregnancy, especially in the first 3 months as it may cause harm to the foetus. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Puricor 50 mg Tablet is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Puricor 50 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Puricor 50 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Puricor 50 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar.

FAQs

Puricor 50 mg Tablet is used to treat acute lymphoblastic leukaemia (blood cancer).
Puricor 50 mg Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.
Puricor 50 mg Tablet may affect eggs or cause low sperm count. Therefore, please consult a doctor before taking Puricor 50 mg Tablet if you are planning to become parents.
Puricor 50 mg Tablet may increase sensitivity to sunlight or UV light. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use a sunscreen before going out in the sun.
Puricor 50 mg Tablet may cause low blood sugar levels in children below 6 years and those having low body weight. Therefore, use Puricor 50 mg Tablet with caution in children and if you notice any symptoms such as dizziness, excessive sweating, confusion or nausea, please consult a doctor immediately.
If you are about to receive any vaccinations especially live vaccines such as measles vaccine, flu vaccine, BCG vaccine, etc., it is advised to inform your doctor that you are on treatment with Puricor 50 mg Tablet as it may cause infections.
Puricor 50 mg Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any signs of infection such as urinary problems, chills, fever, cough, sore throat or mouth and avoid contact with people having cold, flu or infection.

Country of origin

India

Manufacturer/Marketer address

50-Ab, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India
Other Info - PUR0374

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