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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Puricor 50 mg Tablet is used to treat blood cancer. It contains Mercaptopurine that works by inhibiting the growth, repair and multiplication of cancer cells. This medicine may sometimes cause side effects such as vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Vhb Life Sciences Inc

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Puricor 50 mg Tablet

Puricor 50 mg Tablet belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

Puricor 50 mg Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take Puricor 50 mg Tablet as prescribed by your doctor. You are advised to take Puricor 50 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of Puricor 50 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Puricor 50 mg Tablet or any other medicines, please tell your doctor. Avoid taking Puricor 50 mg Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Puricor 50 mg Tablet and for 3 months after completing the course of Puricor 50 mg Tablet to prevent pregnancy. Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as Puricor 50 mg Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Puricor 50 mg Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

Uses of Puricor 50 mg Tablet

Treatment of Blood cancer (Acute lymphoblastic leukaemia)

Medicinal Benefits

Puricor 50 mg Tablet contains Mercaptopurine, an anticancer drug used to treat blood cancer. Puricor 50 mg Tablet interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells. 

Directions for Use

Take Puricor 50 mg Tablet with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Puricor 50 mg Tablet

  • Nausea
  • Vomiting
  • Low red blood cell count
  • Loss of appetite
  • Diarrhoea
  • Inflammation of the mouth

Drug Warnings

If you are allergic to Puricor 50 mg Tablet or any other medicines, please tell your doctor. Avoid taking Puricor 50 mg Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Puricor 50 mg Tablet and 3 months after completing the course of Puricor 50 mg Tablet to prevent pregnancy. Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Puricor 50 mg Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as Puricor 50 mg Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Puricor 50 mg Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking Puricor 50 mg Tablet to cause infections. 

Drug Interactions

Drug-Drug Interaction: Puricor 50 mg Tablet may interact with medicines used to treat gout (thiopurinol, febuxostat, oxipurinol, allopurinol), anti-inflammatory drugs (mesalazine, sulfasalazine, olsalazine), blood thinner (warfarin, acenocoumarol), a drug used to treat various autoimmune diseases (infliximab), anticonvulsants (phenytoin, carbamazepine), antiviral drug (ribavirin).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have TPMT (thiopurine methyltransferase) deficiency, an inherited mutation in the NUDT15-gene (a gene involved in the breakdown of mercaptopurine in the body), Lesch-Nyhan syndrome (a genetic condition), shingles, chickenpox, hepatitis B infection, kidney or liver problems, inform your doctor before taking Puricor 50 mg Tablet .

Drug-Drug Interactions Checker List

  • FEBUXOSTAT
  • ALLOPURINOL
  • MESALAZINE
  • SULFASALAZINE
  • WARFARIN
  • ACENOCOUMAROL
  • INFLIXIMAB
  • PHENYTOIN
  • CARBAMAZEPINE
  • RIBAVIRIN
  • THIOPURINOL
  • OXIPURINOL
  • OLSALAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Puricor 50 mg Tablet as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Special Advise

  • Regular blood and urine tests are recommended while taking Puricor 50 mg Tablet to monitor the number of red blood cells, platelets, white blood cells, uric acid levels, kidney or liver functioning.
  • Do not receive any vaccination during treatment without your doctor's approval while taking Puricor 50 mg Tablet . 

Disease/Condition Glossary

Blood cancer: It is the cancer of blood cells, also known as leukaemia. It causes excessive production of immature white blood cells by the bone marrow. The symptoms include unintentional weight loss, weakness, excessive sweating, tiredness, bone pain, frequent infections, chills or fever, red spots on the skin or painless, swollen lymph nodes, especially in the armpits neck.  The risk factors of leukaemia include smoking, genetic or blood disorders, family history of leukaemia, exposure to high radiation levels, or previous cancer treatment with radiation or chemotherapy.

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Alcohol

Caution

Interaction of Puricor 50 mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Puricor 50 mg Tablet .

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Pregnancy

Unsafe

Puricor 50 mg Tablet is a category D pregnancy drug and is not recommended for use during pregnancy, especially in the first 3 months as it may cause harm to the foetus. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Puricor 50 mg Tablet is contraindicated in breastfeeding women. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Puricor 50 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Puricor 50 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Puricor 50 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Puricor 50 mg Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar.

Country of origin

India

Manufacturer/Marketer address

50-Ab, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India
Other Info - PUR0374

Author Details

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FAQs

Puricor 50 mg Tablet is used to treat acute lymphoblastic leukaemia (blood cancer).
Puricor 50 mg Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Puricor 50 mg Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.
Puricor 50 mg Tablet may affect eggs or cause low sperm count. Therefore, please consult a doctor before taking Puricor 50 mg Tablet if you are planning to become parents.
Puricor 50 mg Tablet may increase sensitivity to sunlight or UV light. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use a sunscreen before going out in the sun.
Puricor 50 mg Tablet may cause low blood sugar levels in children below 6 years and those having low body weight. Therefore, use Puricor 50 mg Tablet with caution in children and if you notice any symptoms such as dizziness, excessive sweating, confusion or nausea, please consult a doctor immediately.
If you are about to receive any vaccinations especially live vaccines such as measles vaccine, flu vaccine, BCG vaccine, etc., it is advised to inform your doctor that you are on treatment with Puricor 50 mg Tablet as it may cause infections.
Puricor 50 mg Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any signs of infection such as urinary problems, chills, fever, cough, sore throat or mouth and avoid contact with people having cold, flu or infection.

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