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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Prothiaden 50 Tablet is used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. It contains Dosulepin, which works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

DOSULEPIN HYDROCHLORIDE

Composition :

DOSULEPIN-50MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Prothiaden 50 Tablet

Prothiaden 50 Tablet belongs to the class of tricyclic antidepressants. It is primarily used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling of loss and might have mood swings. Anxiety is defined as an emotion that is characterized by feelings of tension, worried thoughts, and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

Prothiaden 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Prothiaden 50 Tablet should be taken in dose and duration as advised by the doctor and taking it before bedtime should be preferred as it can make you feel drowsy. It can be taken with or without food, but it should be taken at a fixed time each day. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Most of these side effects of Prothiaden 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own without consulting your doctor as it may lead to withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or breastfeeding. Also, tell your doctor if you are allergic to this medicine.

Uses of Prothiaden 50 Tablet

Treatment of Depression, Anxiety

Directions for Use

Prothiaden 50 Tablet should not be used unless prescribed by a doctor. Always take Prothiaden 50 Tablet exactly as your doctor told you. Your doctor will advise you on how often you take your tablets on the basis of your medical condition. Swallow Prothiaden 50 Tablet with a full glass of water.

Medicinal Benefits

Prothiaden 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Prothiaden 50 Tablet provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

How Prothiaden 50 Tablet Works

Prothiaden 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.'>Prothiaden 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prothiaden 50 Tablet

  •  Increased heart rate
  • Blurred vision
  • Dizziness
  • Dryness in the mouth
  • Weight gain
  • Sudden lowering of blood pressure on standing
  • Difficulty in urination
  • Constipation

What if I have taken an overdose of Prothiaden 50 Tablet

Do not take more than the prescribed dose of Prothiaden 50 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Prothiaden 50 Tablet should be given with extreme caution in patients having epilepsy (Brain disorder in which brain activity becomes abnormal, causing seizures), impaired liver or kidney function, diabetes, decreased level of sodium in the blood, tendency to easily develop bleedings or bruises, patients receiving electroconvulsive treatment, having coronary heart disease, suffering or have suffered from heart problems or have recently had a heart attack, having a low resting heart-rate, having prolonged severe diarrhoea and vomiting (Being sick) or using diuretics (water tablets), experiencing a fast or irregular heartbeat, fainting, collapse, or dizziness on standing up, which may indicate abnormal functioning of the heart rate and having or previously had eye problems, such as certain kinds of glaucoma (increased pressure in the eye).

Drug-Drug Interactions

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DosulepinAmitriptyline
Severe
DosulepinParoxetine
Severe

Drug-Drug Interactions

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DosulepinAmitriptyline
Severe
How does the drug interact with Prothiaden 50 Tablet:
Coadministration of Amitriptyline and Prothiaden 50 Tablet may increase the risk of irregular heartbeat. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although combining Amitriptyline with Prothiaden 50 Tablet may result in an interaction, it can be used when a doctor recommends it. If you experience sudden dizziness or irregular heartbeats during therapy, contact your doctor immediately. Do not discontinue any medication without consulting a doctor.
DosulepinParoxetine
Severe
How does the drug interact with Prothiaden 50 Tablet:
Coadministration of paroxetine and Prothiaden 50 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Prothiaden 50 Tablet and paroxetine together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, increased heart rate, fever, excessive sweating, blurred vision, muscle spasms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Option for healthy food which in turn will help you to elevate your moods.
  • Exercise daily for at least 30 minutes a day. It will help you to reduce stress and improve your mood. It will also improve your quality of sleep.
  • Take deep breaths to calm your mind.
  • Follow a consistent sleep schedule (at least 8 hours a day).
  • Manage your stress levels by doing activities that make you happy such as watching your favourite show, reading a book, listening to music, and activities of your interest.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Prothiaden 50 Tablet Substitute

Substitutes safety advice
  • Dothip-50 Tablet 15's

    by Others

    8.37per tablet
  • Prothimets-50 Tablet 15's

    by Others

    27.54per tablet
  • Depnoc 50 mg Tablet 10's

    by Others

    9.90per tablet
  • Elate-50 Tablet 10's

    by Others

    6.75per tablet
  • Osule 50 Tablet 10's

    by Others

    12.96per tablet
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Alcohol

Unsafe

It is not recommended to take alcohol while taking Prothiaden 50 Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

It is advised not to take Prothiaden 50 Tablet during pregnancy as it may pose risk to the unborn baby. However, if you are already taking Prothiaden 50 Tablet , please inform your doctor that you are pregnant.

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Breast Feeding

Safe if prescribed

Prothiaden 50 Tablet passes in very small amounts in breast milk. It has not been linked with any side-effects. However, caution is advised while taking it. Please inform your doctor if you are breastfeeding.

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Driving

Unsafe

It is not recommended to drive after taking Prothiaden 50 Tablet as it can make you feel drowsy.

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Liver

Caution

Caution is advised while taking Prothiaden 50 Tablet if you suffer or have suffered from liver diseases.

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Kidney

Caution

Caution is advised while taking Prothiaden 50 Tablet if you suffer or have suffered from kidney diseases.

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Children

Unsafe

Prothiaden 50 Tablet is not recommended in children below 12 years of age.

FAQs

Prothiaden 50 Tablet is used to treat depression and anxiety. It works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety.

Prothiaden 50 Tablet helps to elevate your mood levels. After taking it, you easily communicate with other people. It helps you to get better sleep. It helps you to feel like yourself again.

It depends on your symptoms according to which your doctor will advise the dose and duration of Prothiaden 50 Tablet . Please inform your doctor if you are planning to switch to any other antidepressant.

Prothiaden 50 Tablet is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.

No, Prothiaden 50 Tablet is not a habit-forming drug. However, it can cause side-effects especially when you stop taking it suddenly.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - PRO0551

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