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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:25 PM IST
PROMISTIN 1MILLION IU INJECTION is used to treat bacterial infections. It contains Colistimethate which works by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as stomach upset, itching, rash, and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Fusion Health Care Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About PROMISTIN 1MILLION IU INJECTION

PROMISTIN 1MILLION IU INJECTION belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. PROMISTIN 1MILLION IU INJECTION does not work against infections caused by a virus.

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor. You are advised to take PROMISTIN 1MILLION IU INJECTION for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of PROMISTIN 1MILLION IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly.

Uses of PROMISTIN 1MILLION IU INJECTION

Treatment of Several bacterial infections

Medicinal Benefits

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. PROMISTIN 1MILLION IU INJECTION binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. PROMISTIN 1MILLION IU INJECTION is used when other antibiotics are not suitable.

Directions for Use

PROMISTIN 1MILLION IU INJECTION will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PROMISTIN 1MILLION IU INJECTION

  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

Drug Warnings

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly. Inform your anesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor for effective results.

Drug Interactions

Drug-Drug Interaction: PROMISTIN 1MILLION IU INJECTION may interact with antibiotics (amikacin, netilmicin, tobramycin, gentamicin, erythromycin, clarithromycin, azithromycin, ciprofloxacin, norfloxacin, ofloxacin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have myasthenia gravis (muscle weakness), kidney problems or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION.

Drug-Drug Interactions Checker List

  • AMIKACIN
  • NETILIMICIN
  • TOBRAMYCIN
  • GENTAMICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of PROMISTIN 1MILLION IU INJECTION to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking PROMISTIN 1MILLION IU INJECTION.
  • Avoid alcohol consumption as it may increase adverse effects.

Special Advise

  • Regular blood tests are recommended to monitor the levels of PROMISTIN 1MILLION IU INJECTION in blood and kidney functioning.
  • Inform your anaesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anaesthesia.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grows in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have cell wall). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness.

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Alcohol

Caution

Interaction of PROMISTIN 1MILLION IU INJECTION with alcohol is unknown. Please consult a doctor before consuming alcohol while using PROMISTIN 1MILLION IU INJECTION.

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Pregnancy

Caution

PROMISTIN 1MILLION IU INJECTION is a category C pregnancy drug and is given to pregnant women only if it is essential. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

PROMISTIN 1MILLION IU INJECTION may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems or dizziness. Therefore, avoid driving if you experience any of these symptoms after taking PROMISTIN 1MILLION IU INJECTION.

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Liver

Caution

Take PROMISTIN 1MILLION IU INJECTION with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take PROMISTIN 1MILLION IU INJECTION with caution, especially if you have a history of Kidney diseases/conditions as PROMISTIN 1MILLION IU INJECTION may affect kidney function. The dose may be adjusted by your doctor as required.

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Children

Caution

PROMISTIN 1MILLION IU INJECTION should be used with caution in children and in doses as prescribed by a doctor. Special care should be taken in new-born and premature babies as kidneys are not developed fully.

Country of origin

INDIA

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - PRO1182

Author Details

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FAQs

PROMISTIN 1MILLION IU INJECTION is used to treat bacterial infections.
PROMISTIN 1MILLION IU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.
You are not recommended to take PROMISTIN 1MILLION IU INJECTION with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking PROMISTIN 1MILLION IU INJECTION with other medicines.
PROMISTIN 1MILLION IU INJECTION may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking PROMISTIN 1MILLION IU INJECTION. However, if the condition persists or worsens, please consult a doctor.
PROMISTIN 1MILLION IU INJECTION should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be adjusted accordingly.
You are recommended to take PROMISTIN 1MILLION IU INJECTION with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking PROMISTIN 1MILLION IU INJECTION. Therefore, inform your doctor if you have any kidney problems before taking PROMISTIN 1MILLION IU INJECTION.
Before taking PROMISTIN 1MILLION IU INJECTION, inform your doctor if you have a history of kidney problems, myasthenia gravis (a condition that causes muscle weakness), porphyria (a blood disorder), or asthma. These conditions may affect your treatment or require special monitoring.
PROMISTIN 1MILLION IU INJECTION is given by a healthcare professional as an infusion over 30–60 minutes or as a rapid injection within 5 minutes into a vein. Do not self-administer.
Do not use PROMISTIN 1MILLION IU INJECTION if you are allergic to its active substances or any other polymyxins (group of antibiotics to treat bacterial infection). If you are unsure, consult your doctor before receiving PROMISTIN 1MILLION IU INJECTION.
PROMISTIN 1MILLION IU INJECTION is prescribed during pregnancy only if your doctor thinks that the benefits are greater than the potential risks. The safety of PROMISTIN 1MILLION IU INJECTION during pregnancy has not been fully established. Therefore, consult your doctor before taking PROMISTIN 1MILLION IU INJECTION if you are pregnant.
PROMISTIN 1MILLION IU INJECTION is safe when used as per the dose and duration advised by a doctor.
PROMISTIN 1MILLION IU INJECTION causes side effects such as dizziness, stomach upset, tingling, and difficulty in breathing. However, these do not require any medical treatment and gradually reduce over time. Contact a doctor if these side effects persist for longer durations.

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