Prolet-50 Tablet is used to control various epileptic conditions (fits), prevent seizures and treat shaking attacks (essential tremors). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain, leading to seizures, unusual behaviour, and loss of awareness. Prolet-50 Tablet is ineffective for treating absence (petit mal) seizures.

Prolet-50 Tablet contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Prolet-50 Tablet prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only. 

Take Prolet-50 Tablet with or without food. You are advised to take Prolet-50 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, impaired coordination, and nystagmus (involuntary eye movement). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition, effectually continue taking Prolet-50 Tablet for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Prolet-50 Tablet suddenly without consulting your doctor, as it may lead to increased seizures. Avoid taking Prolet-50 Tablet if you are pregnant or breastfeeding unless prescribed. Prolet-50 Tablet should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Prolet-50 Tablet as it might increase side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Prolet-50 Tablet belongs to the group of anticonvulsant medicines. It contains Primidone, which is used to control epilepsy (fits). Prolet-50 Tablet is also used to control and prevent fits during or after a severe head injury or brain surgery. Prolet-50 Tablet is also used to treat trigeminal neuralgia (facial nerve pain). Prolet-50 Tablet works by controlling the overactivity of the brain that causes seizures (fits). Thereby, Prolet-50 Tablet helps in controlling epileptic fits involving muscle spasms and jerking.

• Headache
• Nausea
• Dizziness
• Drowsiness
• Low energy
• Vomiting
• Vertigo
• Visual impairment
• Impaired coordination
• Nystagmus (involuntary eye movement)

Do not take Prolet-50 Tablet if you are allergic to any of its contents. Do not skip doses or stop taking Prolet-50 Tablet suddenly without consulting your doctor, as Prolet-50 Tablet may cause increased seizures. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Prolet-50 Tablet if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Prolet-50 Tablet as it might cause unpleasant side effects. Prolet-50 Tablet should not be used by children unless prescribed. Let your doctor know if you have diabetes, as intake of Prolet-50 Tablet affects the blood sugar level. Intake of Prolet-50 Tablet may cause dizziness, so be cautious while driving or operating heavy machinery.

Drug-Drug Interaction: Prolet-50 Tablet may have interaction with a blood thinner (fluindione, phenindione, warfarin), other medicines used to treat epilepsy (phenytoin, felbamate, valproic acid, carbamazepine, lamotrigine), immunosuppressants (cyclosporine, tacrolimus, sirolimus, everolimus), steroids (dexamethasone, prednisone), antidepressants (lurasidone, lamotrigine), anti-cancer (cyclophosphamide), antimalaria (quinine), HIV medicines (boceprevir, cobicistat, lopinavir), asthma medicines (theophylline, montelukast).

Drug-Food Interaction: Prolet-50 Tablet is known to interact with St. John's wort (an antidepressant herbal supplement).

Drug-Disease Interaction: Prolet-50 Tablet may have interactions with heart problems, diabetes, asthma, alcoholism, porphyria (a rare inherited disorder of metabolism), blood disorders, and kidney or liver problems.

• FLUINDIONE
• PHENINDIONE
• WARFARIN
• PHENYTOIN
• FELBAMATE
• VALPROIC ACID
• CARBAMAZEPINE
• LAMOTRIGINE
• OXCARBAZEPINE
• DEXAMETHASONE
• CYCLOSPORINE
• TACROLIMUS
• SIROLIMUS
• EVEROLIMUS
• PREDNISONE
• LURASIDONE
• CYCLOPHOSPHAMIDE
• LOPINAVIR
• BOCEPREVIR
• COBICISTAT
• THEOPHYLLINE
• MONTELUKAST

• Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
• Meditation, walking, participating in a task, and smelling a strong odour are a few self-control methods for preventing seizures.
• Acupuncture therapy may also be helpful.
• Rest properly. Avoid stress by doing meditation or yoga.

• Your doctor may advise you to get regular blood tests to check for any abnormality of blood and test the amount of Prolet-50 Tablet in your blood. 
• Monitor your blood sugar level regularly while taking Prolet-50 Tablet .

Epilepsy: It is a central nervous system disorder in which brain activity becomes abnormal, leading to rapid fits/seizure episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol, and skipping meals/overeating are a few of the most common triggers for seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders.