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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
PROFOL INJECTION 1% is used in giving anesthesia for major surgical procedures. It is given as induction therapy before surgery to sedate the patient. It contains Propofol, which causes loss of consciousness, that is reversible. It may cause side effects such as dizziness, low blood pressure, nausea, headache, vomiting, local site pain, changes in your breathing pattern and slow heartbeat.
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Composition

PROPOFOL-10MG

Manufacturer/Marketer

Core Claris Lifesciences Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About PROFOL INJECTION 1%

PROFOL INJECTION 1% belongs to a class of drugs known as 'general anesthetic', primarily used in giving anesthesia for major surgical procedures. It is given as induction therapy before surgery to sedate the patient. General Anaesthesia is a medication given before surgery to put you to sleep so that you do not feel the pain as you are unconscious.

PROFOL INJECTION 1% contains Propofol, which is used as an anesthetic for surgeries so that procedure is carried out without pain and distress. It works by causing loss of consciousness, which is reversible. It generally slows down the brain and central nervous system, which is the conscious center.

Take PROFOL INJECTION 1% as prescribed by your doctor. You are advised to take PROFOL INJECTION 1% for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience dizziness, hypotension (low blood pressure), nausea, headache, vomiting, local site pain, changes in your breathing pattern, slow heartbeat. Most of these side effects of PROFOL INJECTION 1% do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take PROFOL INJECTION 1% if you are allergic to PROFOL INJECTION 1% or any of its ingredients. PROFOL INJECTION 1% should always be given by a doctor or a trained professional as over-dose can cause excessive sedation, which can be fatal. Do not drive a car or operate any machinery as PROFOL INJECTION 1% affects alertness. If you are pregnant, planning got conceive or are breastfeeding, PROFOL INJECTION 1% should be taken only after informing your doctor. 

Uses of PROFOL INJECTION 1%

Management of General Anaesthesia.

Medicinal Benefits

PROFOL INJECTION 1% belongs to a class of drugs known as 'general anesthetic,' containing Propofol, primarily used in giving anesthesia for major surgical procedures. It allows the procedures to be carried out without pain and distress. It works by causing loss of consciousness, which is reversible. It generally slows down the brain and central nervous system, which is the conscious center. It is also used in people on a ventilator or who need critical care to sedate the patient.

Directions for Use

PROFOL INJECTION 1% will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PROFOL INJECTION 1%

  • Hypotension (low blood pressure)
  • Nausea 
  • Headache
  • Vomiting
  • Dizziness
  • Local site pain
  • Changes in your breathing pattern
  • Slow heartbeat

Drug Warnings

Do not take PROFOL INJECTION 1% if you are allergic to PROFOL INJECTION 1% or any of its ingredients. PROFOL INJECTION 1% should always be administered by a doctor or a trained professional as over-dose can cause excessive sedation which can be fatal. Do not drive or operate any machinery as PROFOL INJECTION 1% affects alertness. If you are pregnant, planning got conceive or are breastfeeding, PROFOL INJECTION 1% should be taken only after informing your doctor. Maintain a gap of 24 hours after using PROFOL INJECTION 1% and breastfeeding. The doctor will constantly monitor your blood pressure, oxygen level, breathing pattern and kidney function while the surgery goes on.

Drug Interactions

Drug-Drug Interaction: PROFOL INJECTION 1% is known to interact with tuberculosis medication (rifampicin), anti-epilepsy medicines (lorazepam, diazepam), heart medicines (diltiazem, verapamil), antibiotics (ciprofloxacin), water pills (furosemide), mental illness medicines (midazolam, alprazolam). 

Drug-Food Interaction: PROFOL INJECTION 1% should not be taken along with alcohol as it might further increase sleepiness.

Drug-Disease Interaction: PROFOL INJECTION 1% is known to interact in patients who have or ever had fits, high levels of fat in the blood, dehydration (lost lots of water), heart, liver or kidney problems, and mitochondrial disease.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • LORAZEPAM
  • DIAZEPAM
  • DILTIAZEM
  • VERAPAMIL
  • CIPROFLOXACIN
  • FUROSEMIDE
  • MIDAZOLAM
  • ALPRAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Do not consume alcohol while taking PROFOL INJECTION 1% as it might increase the sedation.
  • Eat a low-calorie diet generally home-cooked for a speedy recovery.
  • Avoid junk food, oily and spicy food as you have undergone surgery.
  • Also, in case of sleep disturbances, try to spend time with family, which will change your mood and help you to fall asleep.
  • Limit the screen time as it also alters your sleep cycle.

Special Advise

  • Do not self administer PROFOL INJECTION 1% . It should be done by a doctor only.
  • Constant monitoring of breathing pattern, blood pressure, oxygen levels, kidney function is required.

Disease/Condition Glossary

General Anaesthesia: It is a medication given before surgery to put you to sleep so that you do not feel the pain as you are unconscious. It is more than sleep as the brain does not respond to the pain signals. A trained person who is specialized in anaesthesia generally gives the anesthesia as an intravenous infusion or injection form.

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Alcohol

Unsafe

PROFOL INJECTION 1% can affect alertness if taken along with alcohol. So, the consumption of alcohol should be avoided as it might further reduce alertness.

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Pregnancy

Unsafe

PROFOL INJECTION 1% is not recommended in the last trimester of the pregnancy as it may affect the baby's brain's growth.

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Breast Feeding

Unsafe

PROFOL INJECTION 1% is known to pass through the breastmilk. So, it is not advised to take PROFOL INJECTION 1% during breastfeeding. Consult your doctor for further advice.

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Driving

Unsafe

PROFOL INJECTION 1% can affect alertness and coordination as it is known to cause drowsiness. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

PROFOL INJECTION 1% to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

PROFOL INJECTION 1% to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

PROFOL INJECTION 1% is not recommended for children below the age of 3 years. For children aged above three, take in dose and duration advised by a doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Claris Corporate Headquarters, Nr. Parimal Crossing, Ellisbridge, Ahmedabad-380006, Gujarat, India
Other Info - PRO0114

Author Details

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FAQs

PROFOL INJECTION 1% is used in giving anesthesia for major surgical procedures. It is given as induction therapy before surgery to sedate the patient.
PROFOL INJECTION 1% belongs to a class of drugs known as 'general anesthetic,'Â containing Propofol, primarily used in giving anesthesia for major surgical procedures. It generally slows down the brain and central nervous system, which is the conscious center.
The most common side effects of PROFOL INJECTION 1% include hypotension (low blood pressure), nausea, headache, vomiting, dizziness, local site pain, changes in your breathing pattern, slow heartbeat. Most of these side effects of PROFOL INJECTION 1% do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
It is advised that you should not take PROFOL INJECTION 1% if you are allergic to eggs as it may cause an allergic reaction which can be serious. It is best to inform your doctor and do as advised for the best results.
The doctor will constantly monitor your breathing pattern, blood pressure, oxygen levels, kidney function and other vital signs while taking PROFOL INJECTION 1% .
No, PROFOL INJECTION 1% is not a narcotic, it is a general anesthetic used to sedate before major surgery. It has some addictive effect, which is still being studied.
Yes, PROFOL INJECTION 1% is known to cause hypotension (low blood pressure). So, constant monitoring of blood pressure is required while you undergo surgery to avoid any sudden drop in blood pressure, which can be fatal.

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