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Reviewed By Praneetha Akunuri , M.Pharmacy

Profast 40mg Tablet is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour), duodenal ulcer, gastric ulcer and Crohn's Disease-associated Ulcers. It contains Pantoprazole, which reduces the amount of acid your stomach makes. It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

PANTOPRAZOLE-40MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Profast 40mg Tablet

Profast 40mg Tablet belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Profast 40mg Tablet helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump). This proton pump lies in the cells of the stomach wall and is responsible for the release of gastric acid secretion, damaging tissues in the food pipe, stomach and duodenum. Profast 40mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Profast 40mg Tablet may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain).  These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Profast 40mg Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Profast 40mg Tablet or will have an endoscopy in the future. Prolonged intake of Profast 40mg Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis.

Uses of Profast 40mg Tablet

Profast 40mg Tablet is used to treat peptic ulcers, heartburn, and hyperacidity. The following are the specific applications of Profast 40mg Tablet:
• Gastric reflux disease (GERD): Profast 40mg Tablet is frequently used to treat GERD by decreasing the production of stomach acid, which lessens the symptoms of acid reflux and heartburn.
• Erosive Esophagitis: This medication efficiently promotes healing and symptom relief for this ailment, which is brought on by inflammation and damage to the esophagus as a result of acid reflux.
• Peptic Ulcers: By lowering stomach acid, Profast 40mg Tablet can be used to treat peptic ulcers and promote the healing of the affected areas.
• Zollinger-Ellison Syndrome: This uncommon ailment results in an overabundance of stomach acid. Profast 40mg Tablet considerably lowers acid secretion, which aids with symptom management.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Granules for Suspension: Firstly, shake the container and open the cap. Add the granules from the packet to a cup containing 1 teaspoon of applesauce or apple juice. Mix well for 5 seconds and make your child drink immediately. Profast 40mg Tablet should be given 30 min before meals.

Medicinal Benefits

Profast 40mg Tablet is effective in healing erosive esophagitis (inflammation of the food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers. Profast 40mg Tablet works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.

How Profast 40mg Tablet Works

Profast 40mg Tablet helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump). This proton pump is located in the cells of the stomach wall and is responsible for releasing gastric acid, which can damage tissues in the food pipe, stomach, and duodenum. Profast 40mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Profast 40mg Tablet

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Flatulence
  • Dizziness
  • Arthralgia (joint pain)

What if I have taken an overdose of Profast 40mg Tablet

Do not take more than the prescribed dose of Profast 40mg Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Profast 40mg Tablet if you are allergic to Profast 40mg Tablet or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, are pregnant or planning for pregnancy or are breastfeeding mothers. Profast 40mg Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Profast 40mg Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Profast 40mg Tablet may mask the symptoms of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool), immediately consult the doctor.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
PantoprazoleAtazanavir
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Profast 40mg Tablet:
Co-administration of Rilpivirine is taken with Profast 40mg Tablet, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Profast 40mg Tablet with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazoleAtazanavir
Severe
How does the drug interact with Profast 40mg Tablet:
Co-administration of Profast 40mg Tablet reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Profast 40mg Tablet with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleErlotinib
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Erlotinib with Profast 40mg Tablet may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Profast 40mg Tablet with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleMethotrexate
Severe
How does the drug interact with Profast 40mg Tablet:
Co-administration of Methotrexate with Profast 40mg Tablet can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Profast 40mg Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleDacomitinib
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Profast 40mg Tablet can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Profast 40mg Tablet with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDasatinib
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Dasatinib with Profast 40mg Tablet may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Profast 40mg Tablet with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Nelfinavir with Profast 40mg Tablet may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Profast 40mg Tablet with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazolePazopanib
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Profast 40mg Tablet with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Profast 40mg Tablet and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleGefitinib
Severe
How does the drug interact with Profast 40mg Tablet:
Taking Gefitinib with Profast 40mg Tablet reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Profast 40mg Tablet with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Profast 40mg Tablet to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid consuming foods or drinks that trigger acid reflux or heartburn, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat foods, and spicy foods.
  • Before going to sleep, raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backing up into your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing the backflow of the stomach acid into the food pipe.
  • Include high-fibre-containing foods, such as berries, cherries, leafy green veggies (like kale and spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H. pylori infection.
  • Avoid sitting for long periods, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Profast 40mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Drinking alcohol with Profast 40mg Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Profast 40mg Tablet.

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Pregnancy

Caution

It is not known whether Profast 40mg Tablet affects the baby or not. So, contact a doctor before intake of Profast 40mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Caution

Profast 40mg Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Profast 40mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, Profast 40mg Tablet may cause dizziness, sleepiness, or blur vision. If you observe these symptoms, do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Profast 40mg Tablet should be taken with caution if you have liver problems.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking Profast 40mg Tablet.

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Children

Caution

Profast 40mg Tablet is not be prescribed for children under 5 years of age. It is generally prescribed from 5-16 years of children for the treatment of gastroesophageal reflux disease (GERD).

FAQs

Profast 40mg Tablet is used to treat Hyperacidity, Heartburn, and Peptic ulcer.

Profast 40mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backs up and enters the upper part of the oesophagus, causing heartburn. On the other hand, gas is a byproduct of digestion, eliminating gases like carbon dioxide, hydrogen, nitrogen, and methane from the body.

Yes. Profast 40mg Tablet can alter specific medical tests, such as neuroendocrine tumour (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such tests, contact your doctor.

Prolonged intake of Profast 40mg Tablet may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

No. Profast 40mg Tablet prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If blood is present in your stool or mucus, contact your doctor immediately.

Prolonged intake of Profast 40mg Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin-enhancing medications to cope with long-term side effects.

No. Profast 40mg Tablet is not prescribed for stomach cancer. Do not take Profast 40mg Tablet until your doctor has prescribed it to you. Profast 40mg Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

You should start to feel better in 2-3 days of starting Profast 40mg Tablet. However, it might take up to 4 weeks for Profast 40mg Tablet to work properly. Consult a doctor if you don't feel better or if your condition doesn't improve.

A single dose of Profast 40mg Tablet may not be sufficient. To treat your condition properly, take Profast 40mg Tablet in the dose and for the duration prescribed by your doctor.

Yes, it is safe to take Profast 40mg Tablet if your doctor prescribes it. It is a well-tolerated medicine.

Profast 40mg Tablet is usually prescribed for a short term. However, in some cases, it may be indicated in the long-term management of reflux oesophagitis. If you take Profast 40mg Tablet on a long-term basis (longer than 1 year), your doctor will advise regular monitoring.

It is best to take Profast 40mg Tablet 30 minutes to one hour before a meal.

Profast 40mg Tablet should not be discontinued without a doctor’s consultation. To treat your condition effectively, take Profast 40mg Tablet for as long as it has been prescribed. Talk to the doctor if you have any concerns.

Profast 40mg Tablet may cause weight changes as a side effect. Consult the doctor if you notice any weight changes that bother you.

Avoid alcohol consumption as it might make your stomach produce more acid than usual. This can irritate the stomach lining and make your symptoms worse.

Antacids can be taken with Profast 40mg Tablet if prescribed by the doctor. However, maintain a 2-hour gap between Profast 40mg Tablet and antacid medicines.

Eat smaller and more frequent meals. Avoid foods that trigger acidity, such as fatty and fried foods, spicy foods, carbonated drinks, and alcohol. Include non-citrus fruits, vegetables, lean meat, oatmeal, whole-grain bread, and rice in your diet. Do not lie down immediately after eating, and avoid vigorous exercise for at least a couple of hours afterwards.

Yes, it is safe to take painkillers along with Profast 40mg Tablet if advised by the doctor. To prevent stomach upset, painkillers can be taken with or just after a meal.

Profast 40mg Tablet should be swallowed as a whole with water; do not crush, break or chew it. Profast 40mg Tablet should be taken 30-60 minutes before meal.

Take the missed dose as soon as you remember, unless it is time for the scheduled dose. Do not take a double dose to make up for the forgotten dose. Take your next regular dose at the usual time.

In some people, Profast 40mg Tablet may cause side effects such as headaches, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, contact your doctor.

Country of origin

India

Manufacturer/Marketer address

75 BARODA AVENUE P.S. JADAVPUR, P.O. GARIA KOLKATA WB 700084 IN
Other Info - PR88107

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