Procabazi Injection 1.5 ml
MRP ₹8000
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About Procabazi Injection
Procabazi Injection belongs to a group of medicines known as microtubule inhibitors. It is used to treat advanced prostate cancer or metastatic prostate cancer that has already been treated with other medications. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.
Procabazi Injection contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Procabazi Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.
Cabazitaxel is only for use in men. Men using this Procabazi Injection must use effective birth control whenever they have sex during your treatment and four months after their final dose. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding. Cabazitaxel injection may result in a substantial or life-threatening decrease in the number of white blood cells (a kind of blood cell needed to fight infection) in your blood. This increases your chances of developing a serious infection. Inform your doctor if you are 65 or older if you have or have ever had a low number of white blood cells associated with a fever if you have had radiation therapy, or if you are unable to eat a nutritious diet. Before and during treatment, your doctor will conduct laboratory tests to determine the quantity of white blood cells in your blood. If you have a low white blood cell count, your doctor may reduce your dose or stop or postpone your therapy. If your white blood cell count drops, your doctor may prescribe a prescription to help prevent life-threatening problems.
Uses of Procabazi Injection
Procabazi Injection is used in the treatment of Prostate cancer. The detailed uses of Procabazi Injection are as follows:
- Metastatic prostate cancer: Procabazi Injection is used in combination with prednisone to treat metastatic castration-resistant prostate cancer (mCRPC), a form of prostate cancer that continues to progress despite hormone therapy. It is typically prescribed when the cancer has stopped responding to other treatments like docetaxel.
- Chemotherapy-resistant cases: Procabazi Injection is used when previous chemotherapy regimens have failed. It works by disrupting the microtubule network within cancer cells, which is essential for cell division, thereby slowing or stopping the growth of cancer.
- Advanced-stage disease management: Procabazi Injection is used to improve survival and manage symptoms in patients with advanced prostate cancer, helping to reduce pain and delay disease progression.
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Directions for Use
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Procabazi Injection will be administered by a doctor or nurse in a healthcare facility.
- Do not self-administer.
Medicinal Benefits
Procabazi Injection contains Cabazitaxel, which belongs to a group of medicines known as microtubule inhibitors. Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
How Procabazi Injection Works
Storage
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
- Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
- Avoid contact with people who are sick.
- Wash your hands regularly with soap and water.
- Avoid unpasteurized dairy products.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
What if I have taken an overdose of Procabazi Injection
Drug Warnings
Before taking the Procabazi Injection , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood (neutropenia). You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, an infection can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Cabazitaxel injection can produce severe or life-threatening allergic reactions, especially during the first two infusions. Your doctor will give you drugs to prevent an allergic response at least 30 minutes before the Cabazitaxel injection. You should receive your infusion in a medical institution where you may be treated swiftly if you develop an allergic reaction.
Drug-Drug Interactions
Drug-Drug Interactions
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When Procabazi Injection 1.5 ml is taken with Infliximab, it can increase the risk or severity of developing serious infections.
How to manage the interaction:
Co-administration of Procabazi Injection 1.5 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administering clozapine with Procabazi Injection 1.5 ml may increase the risk of neutropenia.
How to manage the interaction:
Although taking Procabazi Injection 1.5 ml and Clozapine together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms - such as a severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Using tofacitinib together with Procabazi Injection 1.5 ml may increase the risk of serious infections.
How to manage the interaction:
Taking Procabazi Injection 1.5 ml with Tofacitinib together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
The use of leflunomide together with Procabazi Injection 1.5 ml may raise the risk of severe infections.
How to manage the interaction:
Taking Procabazi Injection 1.5 ml with Leflunomide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like infection, sore throat, diarrhea, muscle pain, weight loss, fever, or difficulty breathing, contact your doctor immediately. If you experience any discomfort or burning while urinating, let your doctor know. Do not stop using any medications without talking to your doctor.
Coadministration of baricitinib and abatacept can raise the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, baricitinib can be taken with abatacept if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
When Etanercept is used with Procabazi Injection 1.5 ml, the likelihood or severity of infection may increase.
How to manage the interaction:
Although there is a possible interaction between Procabazi Injection 1.5 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Performing yoga may also help in improving both physical and mental health.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast, fried, processed meats, refined carbs and added sugars.
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Alcohol
Unsafe
Avoid alcohol consumption while on treatment with Procabazi Injection .
Pregnancy
Unsafe
-
Breast Feeding
Unsafe
-
Driving
Caution
Procabazi Injection may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.
Liver
Caution
The safety of Procabazi Injection has not been evaluated in patients with liver impairment. Inform your doctor before receiving the Procabazi Injection if you have had a Liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
Kidney failure may occur with Procabazi Injection because of severe infection, loss of too much body fluid (dehydration), and other factors, and may result in death. Your doctor will examine you for this condition and, if necessary, treat you.
Children
Unsafe
The safety and effectiveness of Procabazi Injection in pediatric patients have not been established.
Heart
Exercise caution before using Procabazi Injection in case of heart problems. Please consult your doctor if you have any concerns.
Geriatrics
Caution
Procabazi Injection should be used with caution in elderly patients, as it may increase the risk of dizziness and other side effects.
FAQs
Procabazi Injection is used to treat Prostate cancer.
Procabazi Injection contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Based on the medical condition, Procabazi Injection may be given alone or with other medicines used to treat Prostate cancer.
Procabazi Injection is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.
You may not be able to get your partner pregnant after treatment with this drug. If you plan to have a baby, consult your doctor before beginning treatment. You might be able to store sperm before starting treatment.
Cabazitaxel, a prostate cancer medication, is used to treat prostate cancer.
No, it is unsafe to father a child while taking Procabazi Injection . It is recommended for sexually active men to use condoms while on treatment and for at least four months after their last dose of Procabazi Injection .
Procabazi Injection can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.
It is not a vesicant. Procabazi Injection is a chemotherapeutic drug, used in the treatment of prostate cancer.
The common side effects of Procabazi Injection may include being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately.
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Reference
- https://www.cancerresearchuk.org/about-cancer/treatment/drugs/cabazitaxel
- https://medlineplus.gov/druginfo/meds/a611009.html
- https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/cabazitaxel
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/201023lbl.pdf
- https://www.jevtana.com/
- https://www.nhs.uk/conditions/prostate-cancer/
- https://www.drugs.com/drug-interactions/cabazitaxel-index.html?filter=3
