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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

It is used to treat advanced prostate cancer or metastatic prostate cancer. It contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide. Sometimes, Procabazi Injection may cause side effects such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss).

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Whats That

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Composition :

CABAZITAXEL-60MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Procabazi Injection

Procabazi Injection belongs to a group of medicines known as microtubule inhibitors. It is used to treat advanced prostate cancer or metastatic prostate cancer that has already been treated with other medications. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Procabazi Injection contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

Procabazi Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Cabazitaxel is only for use in men. Men using this Procabazi Injection must use effective birth control whenever they have sex during your treatment and four months after their final dose. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding. Cabazitaxel injection may result in a substantial or life-threatening decrease in the number of white blood cells (a kind of blood cell needed to fight infection) in your blood. This increases your chances of developing a serious infection. Inform your doctor if you are 65 or older if you have or have ever had a low number of white blood cells associated with a fever if you have had radiation therapy, or if you are unable to eat a nutritious diet. Before and during treatment, your doctor will conduct laboratory tests to determine the quantity of white blood cells in your blood. If you have a low white blood cell count, your doctor may reduce your dose or stop or postpone your therapy. If your white blood cell count drops, your doctor may prescribe a prescription to help prevent life-threatening problems.

Uses of Procabazi Injection

Treatment of Prostate cancer

Directions for Use

Procabazi Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.

Medicinal Benefits

Procabazi Injection contains Cabazitaxel, which belongs to a group of medicines known as microtubule inhibitors. Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

How Procabazi Injection Works

Procabazi Injection contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

Side Effects of Procabazi Injection

  • Nausea)
  • Vomiting
  • Neutropenia (lower-than-normal levels of neutrophils)
  • Anemia (lower-than-normal amount of red blood cells)
  • Leukopenia (low white blood cell count)
  • Thrombocytopenia (low platelet level)
  • Diarrhea
  • Fatigue
  • Nausea
  • Vomiting
  • Constipation
  • Asthenia (abnormal weakness)
  • Abdominal pain
  • Hematuria (blood in urine)
  • Back pain
  • loss of appetite
  • Peripheral neuropathy
  • Fever
  • Shortness of breath
  • Altered taste
  • Cough
  • Joint pains
  • Hair loss

What if I have taken an overdose of Procabazi Injection

As Procabazi Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Procabazi Injection may cause sore throat, cough, fever, chills, muscle aches, burning on urination, or other signs of infection, unusual bruising or bleeding, pale skin, shortness of breath, excessive tiredness or weakness, nausea, vomiting, and diarrhoea.

Drug Warnings

Before taking the Procabazi Injection , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood (neutropenia). You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, an infection can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Cabazitaxel injection can produce severe or life-threatening allergic reactions, especially during the first two infusions. Your doctor will give you drugs to prevent an allergic response at least 30 minutes before the Cabazitaxel injection. You should receive your infusion in a medical institution where you may be treated swiftly if you develop an allergic reaction.

Drug-Drug Interactions

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CabazitaxelBaricitinib
Severe
CabazitaxelInfliximab
Severe

Drug-Drug Interactions

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CabazitaxelBaricitinib
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
Coadministration of baricitinib and abatacept can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with abatacept if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
CabazitaxelInfliximab
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
When Procabazi Injection 1.5 ml is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Procabazi Injection 1.5 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CabazitaxelClozapine
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
Co-administering clozapine with Procabazi Injection 1.5 ml may increase the risk of neutropenia.

How to manage the interaction:
Although taking Procabazi Injection 1.5 ml and Clozapine together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms - such as a severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CabazitaxelEtanercept
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
When Etanercept is used with Procabazi Injection 1.5 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Procabazi Injection 1.5 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CabazitaxelLeflunomide
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
The use of leflunomide together with Procabazi Injection 1.5 ml may raise the risk of severe infections.

How to manage the interaction:
Taking Procabazi Injection 1.5 ml with Leflunomide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like infection, sore throat, diarrhea, muscle pain, weight loss, fever, or difficulty breathing, contact your doctor immediately. If you experience any discomfort or burning while urinating, let your doctor know. Do not stop using any medications without talking to your doctor.
CabazitaxelTofacitinib
Severe
How does the drug interact with Procabazi Injection 1.5 ml:
Using tofacitinib together with Procabazi Injection 1.5 ml may increase the risk of serious infections.

How to manage the interaction:
Taking Procabazi Injection 1.5 ml with Tofacitinib together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Procabazi Injection Substitute

Substitutes safety advice
  • Jevtana 60mg Injection 1.5 ml

    81180.00per tablet
  • Kabanat 60mg Injection 1.5 ml

    9856.80per tablet
  • Cabaxan 60Mg/1.5Ml Inj

    by AYUR

    40344.00per tablet
  • Cabapan 60Mg/1.5Ml Inj

    by AYUR

    16395.90per tablet
  • Cazat 60Mg Inj

    by AYUR

    20500.00per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Procabazi Injection .

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Pregnancy

Unsafe

-

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Breast Feeding

Unsafe

-

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Driving

Caution

Procabazi Injection may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

The safety of Procabazi Injection has not been evaluated in patients with liver impairment. Inform your doctor before receiving the Procabazi Injection if you have had a Liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Kidney failure may occur with Procabazi Injection because of severe infection, loss of too much body fluid (dehydration), and other factors, and may result in death. Your doctor will examine you for this condition and, if necessary, treat you.

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Children

Unsafe

The safety and effectiveness of Procabazi Injection in pediatric patients have not been established.

FAQs

Procabazi Injection is used to treat Prostate cancer.
Procabazi Injection contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Based on the medical condition, Procabazi Injection may be given alone or with other medicines used to treat Prostate cancer.
Procabazi Injection is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.
You may not be able to get your partner pregnant after treatment with this drug. If you plan to have a baby, consult your doctor before beginning treatment. You might be able to store sperm before starting treatment.
Cabazitaxel, a prostate cancer medication, is used to treat prostate cancer.
No, it is unsafe to father a child while taking Procabazi Injection . It is recommended for sexually active men to use condoms while on treatment and for at least four months after their last dose of Procabazi Injection .
Procabazi Injection can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.
It is not a vesicant. Procabazi Injection is a chemotherapeutic drug, used in the treatment of prostate cancer.
The common side effects of Procabazi Injection may include being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately.

Country of origin

INDIA

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - PRO1886

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