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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:35 PM IST

Primacort 100 Injection is used to treat allergic and inflammatory conditions. It contains Hydrocortisone, which inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. It also works as a replacement therapy for the natural steroid hormone cortisol. Common side effects of Primacort 100 Injection are acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness, or indigestion.

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Prescription drug

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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Primacort 100 Injection

Primacort 100 Injection belongs to a class of medicines called corticosteroids used to treat symptoms such as redness, swelling, and itching associated with allergic reactions or inflammatory processes. It is used to treat painful, swollen joints and tendons in conditions such as golfer’s elbow or tennis elbow. Also, it is used to improve different conditions such as ulcerative colitis (inflammation of the lower bowel), Crohn’s disease (inflammation of the gut), systemic lupus erythematosus (SLS), Stevens-Johnson syndrome (autoimmune disorder), severe shock due to infection or injury or failure of adrenal glands. Primacort 100 Injection may be used for a short duration when other means do not or insufficiently help in case of severe allergic reactions, severe asthma, chronic bronchitis or emphysema (lung disease that causes shortness of breath), or status asthmaticus (a persistent asthma attack).

Primacort 100 Injection contains 'Hydrocortisone', which inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. It also works as a replacement therapy for the natural steroid hormone cortisol.

Primacort 100 Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Primacort 100 Injection may cause common side effects such as acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness or indigestion. Most of these side effects of Primacort 100 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Hydrocortisone or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, please inform your doctor before receiving Primacort 100 Injection. If you have been vaccinated recently or are about to get vaccinated, inform your doctor before receiving Primacort 100 Injection. If you have an infection, avoid receiving Primacort 100 Injection; if you develop any new infection while on treatment with Primacort 100 Injection, consult a doctor.

Uses of Primacort 100 Injection

Treatment of Allergic and inflammatory conditions

Medicinal Benefits

Primacort 100 Injection contains 'Hydrocortisone', a corticosteroid that works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. Primacort 100 Injection is used to treat painful, swollen joints and tendons in conditions such as golfer’s elbow or tennis elbow. Also, it is used to improve different conditions such as ulcerative colitis (inflammation of the lower bowel), Crohn’s disease (inflammation of the gut), systemic lupus erythematosus (SLS), Stevens-Johnson syndrome (autoimmune disorder), severe shock due to infection or injury or failure of adrenal glands. Primacort 100 Injection may be used for a short duration when other means do not or insufficiently help in case of severe allergic reactions, severe asthma, chronic bronchitis or emphysema (lung disease that causes shortness of breath), or status asthmaticus (a persistent asthma attack). Also, hydrocortisone works as a hormone replacement for cortisol (a natural hormone) when your body does not make enough cortisol as the adrenal cortex does not function properly (ex: Addison's disease). Primacort 100 Injection may be used in combination with other adrenal cortex hormones.

Directions for Use

Primacort 100 Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Primacort 100 Injection

  • Acne
  • Increased hair growth
  • Weight gain
  • Dizziness
  • Nausea
  • Muscle weakness
  • Indigestion

Drug Warnings

If you are allergic to Hydrocortisone or other medicines, please tell your doctor. If you are pregnant or a nursing mother, please inform your doctor before receiving Primacort 100 Injection. If you have been vaccinated recently or are about to get vaccinated, inform your doctor before receiving Primacort 100 Injection. Some people may experience mood changes (feeling depressed or high), difficulty in thinking or being confused and losing their memory, feeling anxious, sleeping problems, feeling, hearing, or seeing things that do not exist, and having strange and frightening thoughts. If you experience any of these problems, please inform your doctor immediately. If you have an infection, avoid receiving Primacort 100 Injection, and if you develop any new infection while on treatment with Primacort 100 Injection, consult a doctor.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking anti-HIV drugs (ritonavir, cobicistat), anticonvulsants (phenobarbital, phenytoin, carbamazepine, primidone), antituberculosis drugs (rifabutin, rifampicin), antidiabetic drugs (insulin, metformin, glibenclamide), oral contraceptives, blood thinners (warfarin), medicines used to treat glaucoma (acetazolamide), non-steroidal anti-inflammatory drugs (aspirin), an ulcer healing drug (carbenoxolone), medicines used to treat myasthenia gravis, diuretics (furosemide, bendroflumethiazide), and orally ingested chemicals used to make x-rays clearer. 

Drug-Food Interactions: Primacort 100 Injection may interact with grapefruit juice. Please discuss this with your doctor before drinking grapefruit juice while receiving the Primacort 100 Injection.

Drug-Disease Interactions: Avoid receiving Primacort 100 Injection if you have a viral infection such as chickenpox, shingles, measles, or any other infection. If you have or have ever had severe depression or bipolar disorder, tuberculosis (TB), glaucoma (increased pressure in the eye), high blood pressure, fits, osteoporosis (thinning of bones), diabetes, heart failure, stomach ulcers, liver or kidney problems, inform your doctor before receiving Primacort 100 Injection.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • COBICISTAT
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • PRIMIDONE
  • RIFABUTIN
  • RIFAMPICIN
  • INSULIN HUMAN
  • METFORMIN
  • GLIBENCLAMIDE
  • ASPIRIN
  • CARBENOXOLONE
  • FUROSEMIDE
  • BENDROFLUMETHIAZIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid the consumption of foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Special Advise

Primacort 100 Injection may increase the risk of infections, especially if taken for a long duration, as it may weaken the immune system. Therefore, it is advised to stay away from people having chickenpox, measles, or shingles as they can be severely affected while on treatment with Primacort 100 Injection.

Disease/Condition Glossary

Inflammation: It is a response generated by damage to living tissues. This response is a defence mechanism to protect the body from injury, infection, or disease. The symptoms of inflammation include redness, pain, swelling, heat, or loss of function. Inflammation can be caused due to certain medications, acute and chronic conditions, or exposure to foreign materials or irritants your body can’t eliminate easily. 

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Alcohol

Consult your doctor

The interaction of Primacort 100 Injection with alcohol is unknown. Please discuss this with your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Primacort 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks, as corticosteroids may increase the risk of low birth weight of the baby.

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Breast Feeding

Caution

Small amounts of Hydrocortisone may be excreted in breast milk. Therefore, if you are a nursing mother, inform your doctor before receiving Primacort 100 Injection. If you are advised to continue breastfeeding while on treatment with Primacort 100 Injection, your baby will need extra checks to ensure she/he is not being affected by Primacort 100 Injection.

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Driving

Caution

Primacort 100 Injection may cause muscle weakness, mood changes or blurred vision. If you experience these symptoms, avoid driving or operating machines.

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Liver

Consult your doctor

If you have a pre-existing or history of liver disease, inform your doctor before receiving Primacort 100 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Primacort 100 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Primacort 100 Injection should be administered carefully to children as prolonged use may interfere with the growth and development of children and cause cataracts.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - PRI0028

Author Details

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FAQs

Primacort 100 Injection is used to treat Allergic and inflammatory conditions.
Primacort 100 Injection contains Hydrocortisone, a corticosteroid that works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. Also, it works as a replacement therapy for the natural steroid hormone cortisol.
Primacort 100 Injection may cause mental problems, especially if given in high doses. However, inform your doctor immediately if you notice mood changes or have depression and suicidal thoughts while on treatment with Primacort 100 Injection.
A blue steroid card consists of patients' instructions and provides information to healthcare providers regarding the details of prescribed steroids. It is given to patients using Primacort 100 Injection for more than three weeks. The patient is advised to carry a steroid card always and show it to the nurse, midwife, doctor, dentist or anyone who treats them.
Primacort 100 Injection may cause side effects such as acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness or indigestion. If the side effects persist or worsen, please consult your doctor.
Yes, Primacort 100 Injection is a steroid. It belongs to a class of medicines called corticosteroids.
Primacort 100 Injection will be administered by a healthcare professional; do not self-administer.
The most common side effect of Primacort 100 Injection is intense pain and swelling in the joint where it was given. This usually improves after a few days. It is helpful to rest the joint for 24 hours after using Primacort 100 Injection and avoid heavy exercise. It might be safe to take painkillers such as paracetamol or ibuprofen if advised by the doctor.

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