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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Primacort 100 Injection is used to treat allergic and inflammatory conditions. It contains Hydrocortisone, which inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. It also works as a replacement therapy for the natural steroid hormone cortisol. Common side effects of Primacort 100 Injection are acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness, or indigestion.

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Primacort 100 Injection

Primacort 100 Injection belongs to a class of medicines called corticosteroids used to treat symptoms such as redness, swelling, and itching associated with allergic reactions or inflammatory processes. It is used to treat painful, swollen joints and tendons in conditions such as golfer’s elbow or tennis elbow. Also, it is used to improve different conditions such as ulcerative colitis (inflammation of the lower bowel), Crohn’s disease (inflammation of the gut), systemic lupus erythematosus (SLS), Stevens-Johnson syndrome (autoimmune disorder), severe shock due to infection or injury or failure of adrenal glands. Primacort 100 Injection may be used for a short duration when other means do not or insufficiently help in case of severe allergic reactions, severe asthma, chronic bronchitis or emphysema (lung disease that causes shortness of breath), or status asthmaticus (a persistent asthma attack).

Primacort 100 Injection contains 'Hydrocortisone', which inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. It also works as a replacement therapy for the natural steroid hormone cortisol.

Primacort 100 Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Primacort 100 Injection may cause common side effects such as acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness or indigestion. Most of these side effects of Primacort 100 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Hydrocortisone or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, please inform your doctor before receiving Primacort 100 Injection. If you have been vaccinated recently or are about to get vaccinated, inform your doctor before receiving Primacort 100 Injection. If you have an infection, avoid receiving Primacort 100 Injection; if you develop any new infection while on treatment with Primacort 100 Injection, consult a doctor.

Uses of Primacort 100 Injection

Treatment of Allergic and inflammatory conditions

Directions for Use

Primacort 100 Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Primacort 100 Injection contains 'Hydrocortisone', a corticosteroid that works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. Primacort 100 Injection is used to treat painful, swollen joints and tendons in conditions such as golfer’s elbow or tennis elbow. Also, it is used to improve different conditions such as ulcerative colitis (inflammation of the lower bowel), Crohn’s disease (inflammation of the gut), systemic lupus erythematosus (SLS), Stevens-Johnson syndrome (autoimmune disorder), severe shock due to infection or injury or failure of adrenal glands. Primacort 100 Injection may be used for a short duration when other means do not or insufficiently help in case of severe allergic reactions, severe asthma, chronic bronchitis or emphysema (lung disease that causes shortness of breath), or status asthmaticus (a persistent asthma attack). Also, hydrocortisone works as a hormone replacement for cortisol (a natural hormone) when your body does not make enough cortisol as the adrenal cortex does not function properly (ex: Addison's disease). Primacort 100 Injection may be used in combination with other adrenal cortex hormones.

How Primacort 100 Injection Works

Primacort 100 Injection contains 'Hydrocortisone', which inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. It also works as a replacement therapy for the natural steroid hormone cortisol.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Primacort 100 Injection

  • Acne
  • Increased hair growth
  • Weight gain
  • Dizziness
  • Nausea
  • Muscle weakness
  • Indigestion

What if I have taken an overdose of Primacort 100 Injection

Since Primacort 100 Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Hydrocortisone or other medicines, please tell your doctor. If you are pregnant or a nursing mother, please inform your doctor before receiving Primacort 100 Injection. If you have been vaccinated recently or are about to get vaccinated, inform your doctor before receiving Primacort 100 Injection. Some people may experience mood changes (feeling depressed or high), difficulty in thinking or being confused and losing their memory, feeling anxious, sleeping problems, feeling, hearing, or seeing things that do not exist, and having strange and frightening thoughts. If you experience any of these problems, please inform your doctor immediately. If you have an infection, avoid receiving Primacort 100 Injection, and if you develop any new infection while on treatment with Primacort 100 Injection, consult a doctor.

Drug-Drug Interactions

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HydrocortisoneIopamidol
Critical
HydrocortisoneMifepristone
Critical

Drug-Drug Interactions

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HydrocortisoneIopamidol
Critical
How does the drug interact with Primacort 100 Injection 1's:
Taking Iopamidol and Primacort 100 Injection 1's together can increase the risk of seizures, meningitis, and inflammation of the spinal membranes.

How to manage the interaction:
Taking Primacort 100 Injection 1's with Iopamidol is not recommended, please consult your doctor before taking it. If you experience any symptoms , consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneMifepristone
Critical
How does the drug interact with Primacort 100 Injection 1's:
Combining Mifepristone and Primacort 100 Injection 1's can reduce the effects of Primacort 100 Injection 1's.

How to manage the interaction:
Taking Primacort 100 Injection 1's with Mifepristone is not recommended, consult a doctor before taking it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneDesirudin
Severe
How does the drug interact with Primacort 100 Injection 1's:
The combined use of Desirudin and Primacort 100 Injection 1's can increase the risk of bleeding, including severe and sometimes haemorrhage.

How to manage the interaction:
co-administration of Desirudin and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneBaricitinib
Severe
How does the drug interact with Primacort 100 Injection 1's:
Coadministration of baricitinib and Primacort 100 Injection 1's can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Primacort 100 Injection 1's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, discomfort or burning when you urinate, abdominal pain, nausea, or vomiting, consult a doctor. Do not discontinue any medication without consulting a doctor.
HydrocortisoneDronedarone
Severe
How does the drug interact with Primacort 100 Injection 1's:
The combined use of Dronedarone and Primacort 100 Injection 1's can increase the risk of irregular heart rhythm.

How to manage the interaction:
co-administration of Dronedarone and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneClarithromycin
Severe
How does the drug interact with Primacort 100 Injection 1's:
The combined use of Clarithromycin and Primacort 100 Injection 1's can increase the blood levels of Primacort 100 Injection 1's.

How to manage the interaction:
Co-administration of Clarithromycin and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts(the lens of the eye becomes progressively opaque, resulting in blurred vision), menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneCiprofloxacin
Severe
How does the drug interact with Primacort 100 Injection 1's:
Taking Primacort 100 Injection 1's with ciprofloxacin may cause tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction, Primacort 100 Injection 1's can be taken with Ciprofloxacin if prescribed by the doctor. However, consult the doctor if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue any medications without consulting a doctor.
HydrocortisoneDinutuximab
Severe
How does the drug interact with Primacort 100 Injection 1's:
The combined use of Dinutuximab and Primacort 100 Injection 1's can increase the risk of infections.

How to manage the interaction:
co-administration of Dinutuximab and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneGemifloxacin
Severe
How does the drug interact with Primacort 100 Injection 1's:
Taking Gemifloxacin and Primacort 100 Injection 1's together can cause tendinitis and tendon rupture.

How to manage the interaction:
Co-administration of gemifloxacin and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneVoclosporin
Severe
How does the drug interact with Primacort 100 Injection 1's:
The combined use of Voclosporin and Primacort 100 Injection 1's can increase the risk of infections and certain kinds of cancer, including skin cancer and cancer of the lymph glands.

How to manage the interaction:
Co-administration of Voclosporin and Primacort 100 Injection 1's can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, severe abdominal pain, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid the consumption of foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS

Primacort 100 Injection Substitute

Substitutes safety advice
  • Cort-S Injection 1's

    41.90per tablet
  • Hydrocort 100 mg Injection 1's

    42.30per tablet
  • Cortireach 100 mg Injection 1's

    by AYUR

    42.30per tablet
  • LYCORTINS INJECTION

    40.50per tablet
  • EFCORLIN 100MG INJECTION

    37.26per tablet
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Alcohol

Consult your doctor

The interaction of Primacort 100 Injection with alcohol is unknown. Please discuss this with your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Primacort 100 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks, as corticosteroids may increase the risk of low birth weight of the baby.

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Breast Feeding

Caution

Small amounts of Hydrocortisone may be excreted in breast milk. Therefore, if you are a nursing mother, inform your doctor before receiving Primacort 100 Injection. If you are advised to continue breastfeeding while on treatment with Primacort 100 Injection, your baby will need extra checks to ensure she/he is not being affected by Primacort 100 Injection.

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Driving

Caution

Primacort 100 Injection may cause muscle weakness, mood changes or blurred vision. If you experience these symptoms, avoid driving or operating machines.

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Liver

Consult your doctor

If you have a pre-existing or history of liver disease, inform your doctor before receiving Primacort 100 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Primacort 100 Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Primacort 100 Injection should be administered carefully to children as prolonged use may interfere with the growth and development of children and cause cataracts.

FAQs

Primacort 100 Injection is used to treat Allergic and inflammatory conditions.
Primacort 100 Injection contains Hydrocortisone, a corticosteroid that works by inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. Also, it works as a replacement therapy for the natural steroid hormone cortisol.
Primacort 100 Injection may cause mental problems, especially if given in high doses. However, inform your doctor immediately if you notice mood changes or have depression and suicidal thoughts while on treatment with Primacort 100 Injection.
A blue steroid card consists of patients' instructions and provides information to healthcare providers regarding the details of prescribed steroids. It is given to patients using Primacort 100 Injection for more than three weeks. The patient is advised to carry a steroid card always and show it to the nurse, midwife, doctor, dentist or anyone who treats them.
Primacort 100 Injection may cause side effects such as acne, increased hair growth, weight gain, dizziness, nausea, muscle weakness or indigestion. If the side effects persist or worsen, please consult your doctor.
Yes, Primacort 100 Injection is a steroid. It belongs to a class of medicines called corticosteroids.
Primacort 100 Injection will be administered by a healthcare professional; do not self-administer.
The most common side effect of Primacort 100 Injection is intense pain and swelling in the joint where it was given. This usually improves after a few days. It is helpful to rest the joint for 24 hours after using Primacort 100 Injection and avoid heavy exercise. It might be safe to take painkillers such as paracetamol or ibuprofen if advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - PRI0028

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