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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods). It contains Desogestrel and Ethinylestradiol, which help to prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition to this, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply. It may cause side effects such as headache, weight increase or decrease, acne, abdominal pain, cramps, and depression. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Medishri Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Prehal-D21 Tablet 21's

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods). Contraception is a procedure that aims to prevent pregnancy and is used in family planning. Dysmenorrhea is irregular and painful periods leading to abdominal pain, digestion problems, fainting, vomiting, and nausea.

Prehal-D21 Tablet 21's contains Desogestrel and Ethinylestradiol, which are primarily used for contraception. It also contains two female sex hormones that help to prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply.

Prehal-D21 Tablet 21's can be taken with or without food, but it can be taken at the same time every day for the best results. Like all medicines, Prehal-D21 Tablet 21's can cause side effects, although not everybody gets them. The most common side effects are headache, weight increase or decrease, acne, abdominal pain, cramps, and depression. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Do not use Prehal-D21 Tablet 21's if you are pregnant or have recently delivered a baby.

Inform your doctor before starting Prehal-D21 Tablet 21's if you are over 35 years, smoke, have or ever had a heart problem, cancer (breast, uterus, or vagina), uterine bleeding, liver or kidney problem. If you have missed a dose or are late by 12 hours, please wear a condom for 5 days during sexual intercourse to avoid unwanted pregnancy. Do not take medicine if you are pregnant already or breastfeeding.  If you have a migraine, please inform your doctor, as taking Prehal-D21 Tablet 21's may increase your headache.

Uses of Prehal-D21 Tablet 21's

Treatment of Contraception and Treatment of dysmenorrhea (irregular periods).

Directions for Use

Swallow Prehal-D21 Tablet 21's as a whole with water; do not crush, break or chew it. Your doctor will suggest how you take the course of Prehal-D21 Tablet 21's.

Medicinal Benefits

Prehal-D21 Tablet 21's is an oral hormonal combination medicine containing Desogestrel and Ethinylestradiol, primarily used for contraception. Prehal-D21 Tablet 21's contains two female sex hormones, progestin, and estrogen, which help prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition to this, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply. Prehal-D21 Tablet 21's is generally taken for 21 days starting from day one of the menstrual cycle, and then for the next 7 days, it is not taken, and the same course is repeated.

How Prehal-D21 Tablet 21's Works

Prehal-D21 Tablet 21's contains Desogestrel and Ethinylestradiol, which are primarily used for contraception. It also contains two female sex hormones that help to prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prehal-D21 Tablet 21's

  • Headache
  • Increase in weight
  • Acne
  • Abdominal pain
  • Cramps
  • Breast pain
  • Depression

What if I have taken an overdose of Prehal-D21 Tablet 21's

Do not take more than the prescribed dose of Prehal-D21 Tablet 21's as it may cause overdose. The symptoms of overdose include vomiting, nausea and vaginal bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you have or have ever had heart disease, hypertension, obesity, cancer (breast, cervix, or uterus), diabetes mellitus, liver or kidney disease, or abnormal uterine bleeding before taking Prehal-D21 Tablet 21's. Smoking may increase the risk of a cardiovascular event in women over 35 years old when taking Prehal-D21 Tablet 21's. Prehal-D21 Tablet 21's does not protect against any sexually transmitted disease or HIV. If pregnancy occurs while you are taking Prehal-D21 Tablet 21's, please consult your doctor to use it as a birth control pill. Do not start using a new medication without telling your doctor. Sometimes, you may experience spotting or bleeding in between missed periods or menstrual periods. If the spotting persists, please consult your doctor. Do not use Prehal-D21 Tablet 21's if you are pregnant or have recently delivered a baby. If you have missed a dose or are late by 12 hours, please wear a condom for 5 days during sexual intercourse to avoid unwanted pregnancy. Do not take medicine if you are pregnant already or breastfeeding. If you have migraines, please inform your doctor, as taking Prehal-D21 Tablet 21's may increase your headache.

Drug-Drug Interactions

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EthinylestradiolTranexamic acid
Critical
DesogestrelDantrolene
Critical

Drug-Drug Interactions

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EthinylestradiolTranexamic acid
Critical
How does the drug interact with Prehal-D21 Tablet 21's:
Taking Prehal-D21 Tablet 21's with Tranexamic acid may increase the risk of blood clot formation.

How to manage the interaction:
Taking Prehal-D21 Tablet 21's with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
DesogestrelDantrolene
Critical
How does the drug interact with Prehal-D21 Tablet 21's:
Using ethinyl estradiol and dantrolene can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Prehal-D21 Tablet 21's with Dantrolene is not recommended, please consult your doctor before taking it. Call a doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
EthinylestradiolPomalidomide
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
Pomalidomide can cause serious blood clots, and taking it with Ethinyl estradiol may enhance the risk.

How to manage the interaction:
Although there is a possible interaction between Pomalidomide and Prehal-D21 Tablet 21's, you can take these medicines together if prescribed by a doctor. However, if you experience chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
EthinylestradiolPhenobarbital
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
When Prehal-D21 Tablet 21's is taken with phenobarbital, Prehal-D21 Tablet 21's may become les effective.

How to manage the interaction:
Although taking phenobarbital and Prehal-D21 Tablet 21's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you use hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer controlled or if you experience unusual bleeding. Do not stop using any medications without talking to a doctor.
EthinylestradiolClindamycin
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
When Prehal-D21 Tablet 21's and clindamycin are taken together, the effects of Clindamycin can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Prehal-D21 Tablet 21's and clindamycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
EthinylestradiolDabrafenib
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
When coupled with Dabrafenib, the blood level of Prehal-D21 Tablet 21's can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Dabrafenib and Prehal-D21 Tablet 21's, but it can be taken if prescribed by a doctor. If you are taking hormone replacement therapy for menopause, you should notify your doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without consulting a doctor.
EthinylestradiolCarfilzomib
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
Carfilzomib can cause serious blood clots and taking it with ethinyl estradiol may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Carfilzomib and Prehal-D21 Tablet 21's, but it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, you should consult a doctor. Do not stop using any medications without a doctor's advice.
EthinylestradiolPrimidone
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
Coadministration of Prehal-D21 Tablet 21's with primidone may decrease the blood levels of Prehal-D21 Tablet 21's and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between primidone with Prehal-D21 Tablet 21's, it can be taken if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EthinylestradiolLetrozole
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
When taken together ethinyl estradiol may interfere with letrozole's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Letrozole and Prehal-D21 Tablet 21's together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
EthinylestradiolThalidomide
Severe
How does the drug interact with Prehal-D21 Tablet 21's:
Taking thalidomide together with Prehal-D21 Tablet 21's may increase the risk of blood clots and that may lead to serious complications.

How to manage the interaction:
Although taking thalidomide and Prehal-D21 Tablet 21's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Do regular exercise to maintain weight fluctuations caused by Prehal-D21 Tablet 21's.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
  • Monitor your blood sugar level and blood pressure regularly to avoid any complications.

Habit Forming

No

Therapeutic Class

GYNECOLOGY RELATED DRUGS

Prehal-D21 Tablet 21's Substitute

Substitutes safety advice
  • Novelon Tablet 21's

    13.54per tablet
  • Ovuloc Tablet 21's

    8.10per tablet
  • Intimacy Plus 3 Tablet 21's

    6.86per tablet
  • Miliana Tablet 21's

    10.97per tablet
  • Destrogen Tablet 21's

    9.15per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Prehal-D21 Tablet 21's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

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Breast Feeding

Caution

Other forms of contraception should be used instead of Prehal-D21 Tablet 21's if you are breastfeeding.

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Driving

Safe if prescribed

Prehal-D21 Tablet 21's has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Prehal-D21 Tablet 21's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Prehal-D21 Tablet 21's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Safety and efficacy of Prehal-D21 Tablet 21's are established in women of reproductive age. But sufficient studies have been performed on women less than 16 years of age. So, take Prehal-D21 Tablet 21's only when prescribed by a doctor.

FAQs

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods).
Prehal-D21 Tablet 21's prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. It also prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply.
Prehal-D21 Tablet 21's does not protect against sexually transmitted disease. It is an oral form of contraception that does not protect against STDs. So, use some other form of contraception to avoid transmission during sexual intercourse.
While taking Prehal-D21 Tablet 21's, do not smoke and also use a condom to avoid any sexually transmitted disease from your partner.
Yes, Prehal-D21 Tablet 21's can cause spotting in between the regular periods. Usually, it does not persist, but if spotting does not reduce, please inform your doctor, as medical attention may be required.
Usually, Prehal-D21 Tablet 21's is prescribed below 35 years and not recommended for women over 35 years. Your doctor may weigh its benefits and prescribe you accordingly.
Yes, Prehal-D21 Tablet 21's is known to cause weight gain. So, to avoid weight gain, do regular exercise, and eat home-cooked food.

Country of origin

India

Manufacturer/Marketer address

C-66, First Floor, Chander Nagar,Janakpuri, Delhi - 110 058
Other Info - PRE2123

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