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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods). It contains Desogestrel and Ethinylestradiol, which help to prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition to this, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply. It may cause side effects such as headache, weight increase or decrease, acne, abdominal pain, cramps, and depression. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer

Medishri Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Prehal-D21 Tablet 21's

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods). Contraception is a procedure that aims to prevent pregnancy and is used in family planning. Dysmenorrhea is irregular and painful periods leading to abdominal pain, digestion problems, fainting, vomiting, and nausea.

Prehal-D21 Tablet 21's contains Desogestrel and Ethinylestradiol, which are primarily used for contraception. It also contains two female sex hormones that help to prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply.

Prehal-D21 Tablet 21's can be taken with or without food, but it can be taken at the same time every day for the best results. Like all medicines, Prehal-D21 Tablet 21's can cause side effects, although not everybody gets them. The most common side effects are headache, weight increase or decrease, acne, abdominal pain, cramps, and depression. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Do not use Prehal-D21 Tablet 21's if you are pregnant or have recently delivered a baby.

Inform your doctor before starting Prehal-D21 Tablet 21's if you are over 35 years, smoke, have or ever had a heart problem, cancer (breast, uterus, or vagina), uterine bleeding, liver or kidney problem. If you have missed a dose or are late by 12 hours, please wear a condom for 5 days during sexual intercourse to avoid unwanted pregnancy. Do not take medicine if you are pregnant already or breastfeeding.  If you have a migraine, please inform your doctor, as taking Prehal-D21 Tablet 21's may increase your headache.

Uses of Prehal-D21 Tablet 21's

Treatment of Contraception and Treatment of dysmenorrhea (irregular periods).

Medicinal Benefits

Prehal-D21 Tablet 21's is an oral hormonal combination medicine containing Desogestrel and Ethinylestradiol, primarily used for contraception. Prehal-D21 Tablet 21's contains two female sex hormones, progestin, and estrogen, which help prevent pregnancy in multiple ways. It prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. In addition to this, it prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply. Prehal-D21 Tablet 21's is generally taken for 21 days starting from day one of the menstrual cycle, and then for the next 7 days, it is not taken, and the same course is repeated.

Directions for Use

Swallow Prehal-D21 Tablet 21's as a whole with water; do not crush, break or chew it. Your doctor will suggest how you take the course of Prehal-D21 Tablet 21's.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prehal-D21 Tablet 21's

  • Headache
  • Increase in weight
  • Acne
  • Abdominal pain
  • Cramps
  • Breast pain
  • Depression

Drug Warnings

Please inform your doctor if you have or have ever had heart disease, hypertension, obesity, cancer (breast, cervix, or uterus), diabetes mellitus, liver or kidney disease, or abnormal uterine bleeding before taking Prehal-D21 Tablet 21's. Smoking may increase the risk of a cardiovascular event in women over 35 years old when taking Prehal-D21 Tablet 21's. Prehal-D21 Tablet 21's does not protect against any sexually transmitted disease or HIV. If pregnancy occurs while you are taking Prehal-D21 Tablet 21's, please consult your doctor to use it as a birth control pill. Do not start using a new medication without telling your doctor. Sometimes, you may experience spotting or bleeding in between missed periods or menstrual periods. If the spotting persists, please consult your doctor. Do not use Prehal-D21 Tablet 21's if you are pregnant or have recently delivered a baby. If you have missed a dose or are late by 12 hours, please wear a condom for 5 days during sexual intercourse to avoid unwanted pregnancy. Do not take medicine if you are pregnant already or breastfeeding. If you have migraines, please inform your doctor, as taking Prehal-D21 Tablet 21's may increase your headache.

Drug Interactions

Drug-Drug interaction: Prehal-D21 Tablet 21's may interact with anti-viral medicines (paritaprevir, ritonavir), blood thinners (aspirin), pain-killer (acetaminophen), anti-anginal drugs (diltiazem), medicines used to treat stomach acid (esomeprazole, fluconazole, omeprazole, letrozole), cyanocobalamin, anti-allergy (cetirizine), antibiotics (moxifloxacin).

Drug-Food Interaction: Prehal-D21 Tablet 21's interacts with non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Also, alcohol consumption and grapefruit juice should not be taken along with Prehal-D21 Tablet 21's.

Drug-Disease Interaction: Inform your doctor if you smoke,  have or have ever had liver or kidney disease, heart disease, hypertension, diabetes mellitus, liver disease, abnormal uterine bleeding, breast, cervix, uterus cancer, or anaemia.

Drug-Drug Interactions Checker List

  • PARITAPREVIR
  • RITONAVIR
  • ASPIRIN
  • ACETAMINOPHEN
  • DILITAZEM

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Do regular exercise to maintain weight fluctuations caused by Prehal-D21 Tablet 21's.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
  • Monitor your blood sugar level and blood pressure regularly to avoid any complications.

Special Advise

  • Consult your doctor if you experience menstrual irregularities such as spotting / missed periods/ bleeding between menstrual periods.
  • Your doctor may advise regular eye tests and liver function tests.

Disease/Condition Glossary

Contraception: It is a procedure that aims to prevent pregnancy. A woman can only get pregnant if a man sperm fertilizes her egg. Contraception aims to prevent this from happening by keeping egg and sperm apart by stopping egg production or not letting the uterus wall become thick. As a result, no fertilization takes place, so contraception is a safe method for family planning.

Dysmenorrhea: It is irregular and painful periods leading to abdominal pain, digestion problems, fainting, vomiting, nausea. Generally, a menstrual cycle is about 25-30 days. But in dysmenorrhea, this cycle may be short or prolonged, leading to excessive pain.

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Alcohol

Caution

You are recommended not to consume alcohol along with Prehal-D21 Tablet 21's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

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Breast Feeding

Caution

Other forms of contraception should be used instead of Prehal-D21 Tablet 21's if you are breastfeeding.

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Driving

Safe if prescribed

Prehal-D21 Tablet 21's has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Prehal-D21 Tablet 21's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Prehal-D21 Tablet 21's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Safety and efficacy of Prehal-D21 Tablet 21's are established in women of reproductive age. But sufficient studies have been performed on women less than 16 years of age. So, take Prehal-D21 Tablet 21's only when prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

C-66, First Floor, Chander Nagar,Janakpuri, Delhi - 110 058
Other Info - PRE2123

FAQs

Prehal-D21 Tablet 21's is used for contraception and in the treatment of dysmenorrhea (irregular and painful periods).
Prehal-D21 Tablet 21's prevents the release of an egg from the ovaries and makes the fluid present in the cervix thick, making it difficult for sperm to enter the womb. It also prevents the thickening of the uterus's inner wall, which is necessary for an egg to grow and multiply.
Prehal-D21 Tablet 21's does not protect against sexually transmitted disease. It is an oral form of contraception that does not protect against STDs. So, use some other form of contraception to avoid transmission during sexual intercourse.
While taking Prehal-D21 Tablet 21's, do not smoke and also use a condom to avoid any sexually transmitted disease from your partner.
Yes, Prehal-D21 Tablet 21's can cause spotting in between the regular periods. Usually, it does not persist, but if spotting does not reduce, please inform your doctor, as medical attention may be required.
Usually, Prehal-D21 Tablet 21's is prescribed below 35 years and not recommended for women over 35 years. Your doctor may weigh its benefits and prescribe you accordingly.
Yes, Prehal-D21 Tablet 21's is known to cause weight gain. So, to avoid weight gain, do regular exercise, and eat home-cooked food.

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