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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:46 PM IST
Pregdox Plus Tablet is used to treat nausea and vomiting during pregnancy. It works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Additionally, it provides essential nutrients required during pregnancy. In some cases, this medicine may cause side effects such as dizziness, drowsiness, dry mouth, tiredness and constipation. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Rekvina Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pregdox Plus Tablet

Pregdox Plus Tablet belongs to the class of medications called ‘anti-emetics’ primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Morning sickness (nausea and vomiting during pregnancy) is a common symptom of pregnancy. It usually begins in the 6th week of pregnancy, lasting up to 16 to 18 weeks. However, some pregnant women have it throughout pregnancy. It can lead to electrolyte imbalances and weight loss in pregnant women.

Pregdox Plus Tablet contains Doxylamine, Pyridoxine, and Folic acid. Doxylamine is an antihistamine that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine is vitamin B6, and its deficiency may cause nausea and vomiting. It works by restoring the levels of vitamin B6 in the body and treating nausea and vomiting during pregnancy. Folic acid is also a form of vitamin B, which can provide essential nutrients during pregnancy.

You should take this medicine exactly as prescribed by the doctor. The common side effects of Pregdox Plus Tablet are dizziness, drowsiness, dry mouth, tiredness and constipation. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Pregdox Plus Tablet if you are allergic to any contents of it. Before taking Pregdox Plus Tablet , inform your doctor if you have asthma, glaucoma (increased pressure in the eye), stomach ulcer, blockage in the stomach and small intestine, blockage in the bladder, and vitamin B12 deficiency. It is not recommended for use in children and breastfeeding mothers. Do not consume alcohol while taking this medicine, as it may increase the risk of side effects. Pregdox Plus Tablet may cause drowsiness and dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Pregdox Plus Tablet

Treatment of Nausea and vomiting during pregnancy.

Medicinal Benefits

Pregdox Plus Tablet belongs to the class of medications called ‘anti-emetics’ primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Pregdox Plus Tablet contains Doxylamine, Pyridoxine, and Folic acid. Doxylamine is an antihistamine that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine is vitamin B6, and its deficiency may cause nausea and vomiting. It works by restoring the levels of vitamin B6 in the body and treating nausea and vomiting during pregnancy. Folic acid is also a form of vitamin B, which can provide essential nutrients during pregnancy.

Directions for Use

Take this medicine before food, i.e. 1 or 2 hours before a meal. Swallow Pregdox Plus Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pregdox Plus Tablet

  • Drowsiness
  • Dizziness
  • Tiredness
  • Dry mouth
  • Constipation

Drug Warnings

Pregdox Plus Tablet is usually prescribed for pregnant women to prevent nausea and vomiting. So, do not use it for any other indication without consulting your doctor. It is not recommended to use Pregdox Plus Tablet along with monoamine oxidase (MAO) inhibitors (antidepressants). In addition, inform your doctor if you are receiving anticoagulant (blood thinners) therapy, sleeping pills, pain killers and cough or cold medicines. Do not stop taking this medicine abruptly as it may lead to the recurrence of your symptoms.

Drug Interactions

Drug-Drug Interactions: Pregdox Plus Tablet may interact with blood thinners, monoamine oxidase inhibitors (selegiline, rasagiline, and tranylcypromine, etc.), sleeping pills (zolpidem, alprazolam, and triazolam, etc.), certain pain medicines (morphine and methadone, etc.), and cough or cold medicines (brompheniramine, chlorpheniramine, and diphenhydramine, etc.).

Drug-Food Interactions: Do not take alcohol while using Pregdox Plus Tablet as it may cause excessive drowsiness. Do not take folate-rich food such as brans and cereal enriched with folic acid while using this medicine.

Drug-Disease Interactions: Pregdox Plus Tablet should be used with caution in patients with asthma, glaucoma (increased pressure in the eye), stomach ulcer, blockage in the stomach and small intestine, blockage in the bladder, and vitamin B12 deficiency.

Drug-Drug Interactions Checker List

  • SELEGILINE
  • RASAGILINE
  • TRANYLCYPROMINE
  • ALPRAZOLAM
  • ZOLPIDEM
  • TRIAZOLAM
  • MORPHINE
  • METHADONE
  • BROMPHENIRAMINE
  • CHLORPHENIRAMINE
  • DIPHENHYDRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep good health and avoid chances of nausea and vomiting.

  • Avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has got lost due to vomiting.

  • Include more cool beverages in your food like clear soup, flavoured gelatin and carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.

Special Advise

  • Pregdox Plus Tablet may cause false-positive results for drugs or pain medicines such as opiates or methadone when a urine drug screen is performed. So, inform your doctor that you are taking Pregdox Plus Tablet before undergoing this test. 

  • Do not take vitamin B supplementation in any form such as diet, multivitamins, or other supplements. 

Disease/Condition Glossary

Morning sickness (nausea and vomiting): It is a common symptom of pregnancy. It is usually happening within the first trimester (first four months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy. Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. Vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain or irritation to the stomach.

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Alcohol

Unsafe

Do not consume alcohol while using Pregdox Plus Tablet as it may cause excessive drowsiness.

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Pregnancy

Safe if prescribed

Pregdox Plus Tablet is recommended to treat nausea and vomiting during pregnancy. So, it is safe if prescribed in pregnant women.

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Breast Feeding

Caution

Pregdox Plus Tablet should be used with caution in breastfeeding mothers as it may pass into breast milk. If prescribed, the doctor may advise you to stop breastfeeding.

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Driving

Caution

Pregdox Plus Tablet may cause dizziness and drowsiness, so do not drive or operate heavy machinery if you are not fully alert.

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Liver

Safe if prescribed

Pregdox Plus Tablet is probably safe in patients with liver diseases.

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Kidney

Safe if prescribed

Pregdox Plus Tablet is probably safe in patients with kidney diseases.

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Children

Unsafe

Pregdox Plus Tablet is not recommended for use in children as safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

328-329, Paradise Complex,Sayajigunj, Baroda 390 005
Other Info - PRE0161

FAQs

Pregdox Plus Tablet is used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy.
Pregdox Plus Tablet contains Doxylamine, Pyridoxine, and Folic acid. Doxylamine is an antihistamine that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine is vitamin B6 and its deficiency may cause nausea and vomiting. It works by restoring the levels of vitamin B6 in the body and treat nausea and vomiting during pregnancy. A folic acid is also a form of vitamin B which can provide essential nutrients during pregnancy.
You should not stop taking Pregdox Plus Tablet even if you feel better as abrupt of this medicine may cause recurrence of symptoms. So, please consult your doctor before discontinuing the medicine.
The common side-effects of Pregdox Plus Tablet are drowsiness, dizziness, tiredness, dry mouth, and constipation. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is advised to take Pregdox Plus Tablet 1 or 2 hours before a meal to prevent nausea and vomiting.
It is not advised to take Pregdox Plus Tablet with certain pain medicines such as morphine which can suppress the central nervous system (brain and spinal cord). Concomitant use of these drugs may increase the risk of side-effects.
Take Pregdox Plus Tablet on an empty stomach, at least 1 hour before or 2 hours after a meal, with a full glass of water. It's typically taken at bedtime, as it may cause drowsiness. However, the timing may vary depending on the severity of symptoms. Always follow your doctor's guidance for personalized instructions.
For pregnant women, Pregdox Plus Tablet offers a safe treatment for nausea and vomiting. However, always consult your doctor before starting any medication during pregnancy to have the best treatment for your health and your baby.
The usual dose for Pregdox Plus Tablet is 2 tablets at bedtime. If symptoms persist, your doctor may recommend 2 tablets at bedtime and 2 tablets in the morning. The maximum dose is 4 tablets per day. The dose suggested is based on your health condition. Always follow your doctor's instructions and do not exceed the recommended dose.
Yes, Pregdox Plus Tablet makes you sleepy. Common side effects of Pregdox Plus Tablet include drowsiness and dizziness, which may cause sleepiness. Typically, these symptoms decrease as your body adapts to the medication. If they worsen or persist, consult your doctor for guidance and relief.
No, Pregdox Plus Tablet is not an antibiotic. It is a combination medication used to manage nausea and vomiting, particularly during pregnancy. Doxylamine is an antihistamine, while pyridoxine (vitamin B6) and folic acid are vitamins that help reduce nausea.
To help with morning sickness, eat small meals often and drink water or ginger tea in small sips. Avoid strong smells and choose plain foods like nuts and bananas. Keep snacks nearby and relax to avoid stress. Wear loose clothes and get fresh air. Ginger and lemon can also help. If it gets worse, see your doctor.
Pregdox Plus Tablet belongs to the class of medications called ‘anti-emetics. It contains Doxylamine, Pyridoxine, and Folic acid. Treat nausea and vomiting in pregnant women especially.
Pregdox Plus Tablet is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
Generally, Pregdox Plus Tablet is used to treat nausea and vomiting but in some rare cases, it occasionally causes nausea and vomiting as a side effect in some individuals due to the appropriate dose or potential interactions.
Feeling dizziness is the most common side effect of the Pregdox Plus Tablet . However, this symptom vanishes as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Pregdox Plus Tablet has specific contraindications, such as hypersensitivity to any of its components and simultaneous use of Monoamine Oxidase Inhibitors (MAOIs), sleeping pills, certain pain medicines, and folate-rich foods due to potential serious interactions. It's crucial to consult a healthcare professional before starting this medication to ensure it's safe and appropriate for your use. Always follow your doctor's guidance to avoid adverse effects and interactions.
Pregdox Plus Tablet may show drug interaction with vitamin B-complex. Dose adjustment is required to avoid negative complications. However, it's always best to consult your doctor or pharmacist before combining supplements to ensure it's safe and appropriate for your specific needs.
Pregdox Plus Tablet is not designed to relieve stomach pain. It is primarily used to treat nausea and vomiting, especially during pregnancy. It is not a pain reliever. For stomach pain consult a doctor for appropriate guidance.
Pregdox Plus Tablet usually doesn't harm the kidneys. However, if you have pre-existing kidney issues or taking kidney-related medications, inform your doctor before taking this medication. They will provide personalized guidance to ensure safe usage.
Never take more than the recommended dose of Pregdox Plus Tablet . Exceeding the prescribed amount can lead to severe side effects. Always follow your doctor's dosage instructions. If you think the current dose isn't working, consult your doctor. They may adjust the dosage or suggest alternative treatments.
Store Pregdox Plus Tablet in its original container, keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
The effectiveness of Pregdox Plus Tablet varies from person to person, depending on individual health, severity of symptoms, dosage, and frequency. Generally, relief can be expected within 1 hour of taking the tablet, with effects lasting up to 24 hours. However, individual results may differ.
Pregdox Plus Tablet is a solid dosage form. A maximum daily dose of Pregdox Plus Tablet is up to 2-4 tablets based on the health status.
Pregdox Plus Tablet is not recommended for children under 18 years old due to a lack of established safety and efficacy. This medication is primarily prescribed for pregnancy-related nausea and vomiting. For paediatric use, consult your doctor for personalized advice, as safety and effectiveness in children have not been established.

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