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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Preganyx-M 75Mg Capsule is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Acinonyx Pharmaceutical Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Preganyx-M 75Mg Capsule

Preganyx-M 75Mg Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Preganyx-M 75Mg Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Preganyx-M 75Mg Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Preganyx-M 75Mg Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Preganyx-M 75Mg Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Preganyx-M 75Mg Capsule may cause dizziness or drowsiness. Preganyx-M 75Mg Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Preganyx-M 75Mg Capsule

Treatment of Neuropathic pain.

Medicinal Benefits

Preganyx-M 75Mg Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Preganyx-M 75Mg Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Preganyx-M 75Mg Capsule

  • Dizziness
  • Drowsiness
  • Headache
  • Anorexia (loss of appetite)
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Sore throat
  • Vision problems
  • Hot sensation (burning pain)
  • Diaphoresis (sweating)
  • Weight gain

Drug Warnings

Preganyx-M 75Mg Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Preganyx-M 75Mg Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Preganyx-M 75Mg Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Preganyx-M 75Mg Capsule , inform your doctor as Preganyx-M 75Mg Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Preganyx-M 75Mg Capsule . In such cases, inform your doctor immediately.  

Drug Interactions

Drug-Drug Interaction: Preganyx-M 75Mg Capsule may interact with a pain killer (oxycodone), opioids, antianxiety drugs (lorazepam), antacid (omeprazole), antibiotic (neomycin), and anti-gout medication (colchicine). 

Drug-Food Interaction: Avoid alcohol consumption while using Preganyx-M 75Mg Capsule . 

Drug-Disease Interaction: Preganyx-M 75Mg Capsule should be used with caution in patients with liver diseases, kidney diseases, heart problems, alcoholism, drug abuse, and suicidal tendencies. 

Drug-Drug Interactions Checker List

  • OXYCODONE
  • LORAZEPAM
  • OMEPRAZOLE
  • COLCHICINE
  • NEOMYCIN

Habit Forming

Yes

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

 

Special Advise

  • Preganyx-M 75Mg Capsule may increase suicidal thoughts. Extreme caution is advised with people suffering from suicidal tendencies or psychological problems.

  • Preganyx-M 75Mg Capsule is known to cause dizziness and sleepiness, so it is advised to refrain from driving or doing any work that requires attention or concentration.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease, infection, or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sense is also a common symptom of neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Preganyx-M 75Mg Capsule is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Preganyx-M 75Mg Capsule should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Preganyx-M 75Mg Capsule may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Preganyx-M 75Mg Capsule .

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Liver

Caution

Preganyx-M 75Mg Capsule should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Preganyx-M 75Mg Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary

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Children

Unsafe

Preganyx-M 75Mg Capsule is not recommended for anyone below the age of 18 years.

Country of origin

INDIA

Manufacturer/Marketer address

2EC-311, East of NGEF layout Kasturinagar, Bangalore-16
Other Info - PRE1344

Author Details

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FAQs

Preganyx-M 75Mg Capsule is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning.
Preganyx-M 75Mg Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Preganyx-M 75Mg Capsule block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.
Preganyx-M 75Mg Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.
Preganyx-M 75Mg Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Preganyx-M 75Mg Capsule should be stopped gradually over a minimum of 1 week.
Preganyx-M 75Mg Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Preganyx-M 75Mg Capsule . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.
Preganyx-M 75Mg Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Preganyx-M 75Mg Capsule .
You may notice pain improvement within 2-3 days after taking Preganyx-M 75Mg Capsule . However, it may take 2-3 months for your symptoms to improve depending on your health condition.
Preganyx-M 75Mg Capsule may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.
Preganyx-M 75Mg Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Preganyx-M 75Mg Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.
Preganyx-M 75Mg Capsule may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).
If you forget to take a dose of Preganyx-M 75Mg Capsule , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.
You are advised to avoid alcohol consumption while taking Preganyx-M 75Mg Capsule as it may increase the risk of side effects. However, if you have any concerns, please discuss with your doctor.
If you have started taking Preganyx-M 75Mg Capsule , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.
Store Preganyx-M 75Mg Capsule at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.
The side effects of Preganyx-M 75Mg Capsule include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.
You are recommended to take Preganyx-M 75Mg Capsule only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.
You are recommended to avoid driving or using any tools or machines until you know how Preganyx-M 75Mg Capsule affects you as it may cause dizziness or drowsiness in some people.

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