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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:08 PM IST
Pregamer Tablet is used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). It contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body. It may cause side efffects such as dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

PREGABALIN-75MG

Manufacturer/Marketer

Mercy Pharma

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Pregamer Tablet

Pregamer Tablet belongs to a group of medications called 'anti-convulsants', primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash), spinal cord injury, and injuries to tissue, muscles, or joints.

Pregamer Tablet contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

In some cases, Pregamer Tablet might cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Tell your doctor if you are facing symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle pain, soreness, weakness, kidney, liver, or heart diseases.  Caution is required before giving Pregamer Tablet to pregnant or breastfeeding women. The safety and effectiveness in children less than 18 years of age have not been established, so Pregamer Tablet should not be given to them.

Uses of Pregamer Tablet

Treatment of Neuropathic pain (nerve pain), Epilepsy (seizures/fits), Fibromyalgia (musculoskeletal pain).

Medicinal Benefits

Pregamer Tablet belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in the body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it.Oral solution/Syrup: Shake the bottle well before use. Take the prescribed dose with the help of a measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pregamer Tablet

  • Dizziness
  • Somnolence (sleepiness/drowsiness)
  • Dry mouth
  • Oedema (fluid overload with swelling)
  • Blurred vision
  • Weight gain

Drug Warnings

Do not take Pregamer Tablet if you are known to be allergic to any of its contents. Inform your doctor if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Caution is required before giving Pregamer Tablet to pregnant or breastfeeding women. The safety and effectiveness of Pregamer Tablet in children under 18 years of age have not been established, so Pregamer Tablet should not be given to them. Taking Pregamer Tablet with opioids analgesics or painkillers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, tell your doctor about this as Pregamer Tablet interacts with these drugs and causes sleepiness, drowsiness and dizziness and affects your daily activity. Immediately contact a doctor if you have swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema).

Drug Interactions

Drug-Drug Interaction: Pregamer Tablet may interact with painkillers (morphine, fentanyl, oxycodone, tramadol, codeine) and medicines for treating anxiety (lorazepam, diazepam, clonazepam).

Drug-Food Interaction: Pregamer Tablet may interact with alcohol. Therefore, avoid consuming alcohol while taking Pregamer Tablet as it may increase side effects such as drowsiness, dizziness, or difficulty concentrating. 

Drug-Disease Interaction: If you have suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, heart problems, liver/kidney impairment, inform your doctor before taking Pregamer Tablet .

Drug-Drug Interactions Checker List

  • MORPHINE
  • FENTANYL
  • OXYCODONE
  • TRAMADOL
  • CODEINE
  • LORAZEPAM
  • DIAZEPAM
  • CLONAZEPAM

Habit Forming

Yes

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, omega-3 rich foods. Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.

  • Do regular exercise and maintain a healthy weight.

  • Avoid the consumption of alcohol as it may increase dizziness or drowsiness.

Special Advise

Do not take Pregamer Tablet for a prolonged time; it may lead to mental or physical dependence on Pregamer Tablet .

Disease/Condition Glossary

Neuropathic pain (nerve pain): It is a chronic nerve pain condition usually caused by damaged or irritated nerves due to conditions like diabetes, shingles (viral infection with painful rash), spinal cord injury, or injuries to tissue/muscles/joints. Symptoms of nerve pain sensation are hot, burning, throbbing, shooting, stabbing, sharp, cramping, tingling, and numbness. 

Fibromyalgia (musculoskeletal pain): It is a chronic condition that may cause pain, muscle stiffness and tenderness, tiredness, difficulty falling asleep or staying asleep and mental distress, an impact on physical and social functioning and overall quality of life.

Epilepsy (fits): It is a nervous system disorder with a sudden rush of electricity in the brain due to disturbed nerve cell (neuron) activity in the brain. Seizures are of two types, namely: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures can make people confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and sleepiness.

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Pregnancy

Caution

Pregamer Tablet is a category C pregnancy drug. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregamer Tablet .

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Breast Feeding

Caution

Pregamer Tablet should be used in breastfeeding women only when prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing Pregamer Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Pregamer Tablet . Pregamer Tablet can also sometimes cause blurry/double vision; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Take Pregamer Tablet with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pregamer Tablet with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pregamer Tablet is not recommended for children below the age of 18 years. The safety and efficacy of Pregamer Tablet have not been established.

Country of origin

India

Manufacturer/Marketer address

621 S New Ballas Rd Tower A Suite 20A, St. Louis, Mo 63141, United States
Other Info - PRE1107

Author Details

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FAQs

Pregamer Tablet is primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve).
Pregamer Tablet works by blocking the pain centre that interferes with pain messages that travel through the brain and spine (central nervous system). In epilepsy, it prevents episodes of fits by reducing the abnormal electrical activity in the brain and calming the overactive nerves.
Yes, Pregamer Tablet may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult the doctor if you have any further concerns about keeping your weight stable.
No, you are not recommended to take Pregamer Tablet with tramadol as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a stage of coma. So, before using Pregamer Tablet with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
No, Pregamer Tablet is not a normal painkiller. It is an anti-convulsant that helps treat neuropathic pain, musculoskeletal pain, and epilepsy.
Do not discontinue Pregamer Tablet without consulting your doctor as it might cause withdrawal symptoms. The doctor will reduce the dose gradually to prevent withdrawal symptoms.
Neuropathic pain occurs due to nerve damage while muscle pain occurs due to spasms or injury. Neuropathic pain is chronic and is felt as tingling and burning sensation. Whereas, muscle pain is a dull ache and will generally get better within a few days unless it is a severe injury.
Pregamer Tablet works in different ways for each disease. For neuropathic and musculoskeletal pain, it calms the damaged or overactive nerves and decreases pain signals sent out by damaged nerves in the body. In case of epilepsy, it reduces abnormal electrical activity in the brain.
Pregamer Tablet starts working within a week and you may notice its full benefits in a few weeks. Continue taking Pregamer Tablet for the prescribed duration for effective results.
Pregamer Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Pregamer Tablet may be addictive. Therefore, take Pregamer Tablet only for the prescribed duration. Do not take Pregamer Tablet for a prolonged time as it may lead to mental or physical dependence.
Taking Pregamer Tablet with diazepam may increase side effects such as dizziness, confusion, drowsiness and difficulty concentrating. Hence, consult the doctor before taking diazepam with Pregamer Tablet .
Pregamer Tablet may cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

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