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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Pregabid NT Tablet is used for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. It contains Pregabalin and Nortriptyline, which affects the chemicals in the brain that send pain signals across the nervous system. Also, it increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. In some cases, you may experience certain common side effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Pregabid NT Tablet is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.

Pregabid NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Pregabid NT Tablet helps to treat neuropathic pain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Pregabid NT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Pregabid NT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabid NT Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Treatment of Neuropathic pain.
Take Pregabid NT Tablet with or without food. Swallow Pregabid NT Tablet as a whole with a glass of water, do not chew or break it.

Pregabid NT Tablet is a combination of two medicines, namely: Pregabalin and Nortriptyline. Pregabid NT Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, Pregabid NT Tablet helps to treat neuropathic pain (pain due to nerve damage).

Pregabid NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Pregabid NT Tablet helps to treat neuropathic pain.
Store in a cool and dry place away from sunlight
  • Dizziness
  • Sleepiness
  • Nausea
  • Blurred vision
  • Peripheral oedema (swelling of lower legs and hands)
  • Weight gain
  • Dry mouth
Do not take more than the prescribed dose of Pregabid NT Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Do not take Pregabid NT Tablet if you are allergic to any of its contents. Inform your doctor before taking Pregabid NT Tablet if you have or had heart problems, bipolar syndrome, severe liver disease or if you have taken MAO inhibitors in the last 14 days. Consult your doctor before taking cough-cold medicines containing adrenaline-like drugs such as ephedrine, phenylpropanolamine, isoprenaline, noradrenaline or phenylephrine. Consult your doctor if you are pregnant or breastfeeding. Pregabid NT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Pregabid NT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabid NT Tablet as it could lead to increased drowsiness and sleepiness.

verifiedApollotooltip
NortriptylineZiprasidone
Critical
NortriptylineTranylcypromine
Critical

Drug-Drug Interactions

NortriptylineZiprasidone
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
NortriptylineTranylcypromine
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylineSelegiline
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Co-administration of Pregabid NT Tablet 15's with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineSafinamide
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
NortriptylineLinezolid
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Using Pregabid NT Tablet 15's together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Pregabid NT Tablet 15's is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NortriptylineDextromethorphan
Severe
How does the drug interact with Pregabid NT Tablet 15's:
Co-administration of Pregabid NT Tablet 15's with Dextromethorphan can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Dextromethorphan together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineEfavirenz
Severe
How does the drug interact with Pregabid NT Tablet 15's:
Coadministration of Pregabid NT Tablet 15's with Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pregabid NT Tablet 15's with Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineBupropion
Severe
How does the drug interact with Pregabid NT Tablet 15's:
Taking bupropion with Pregabid NT Tablet 15's may raise the chance of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Pregabid NT Tablet 15's can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.
No
MISCELLANEOUS

Pregabid NT Tablet Substitute

Substitutes safety advice
  • Pregaba NT Tablet 10's

    23.49per tablet
  • Pregalin NT Tablet 10's

    by AYUR

    22.46per tablet
  • Pregeb NT 75 mg/10 mg Tablet 10's

    by AYUR

    22.41per tablet
  • Pbren-NT Tablet 10's

    23.49per tablet
  • Maxgalin NT Tablet 15's

    22.20per tablet
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FAQs

Pregabid NT Tablet is used to treat neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc.
Pregabid NT Tablet affects the chemicals in the brain that send pain signals across the nervous system. It increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain.
Dry mouth could be a side-effect of Pregabid NT Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
To treat your condition effectually, continue taking Pregabid NT Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregabid NT Tablet .
Pregabid NT Tablet is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.
Pregabid NT Tablet may cause peripheral oedema. Peripheral oedema is the swelling of hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
Pregabid NT Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Pregabid NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, they help treat neuropathic pain.
When taking Pregabid NT Tablet , you must be mindful of your diet and lifestyle to maintain a healthy weight. This medication combination can increase your appetite, leading to weight gain. Focus on nutrient-dense foods, be mindful of your portion sizes, and avoid high-calorie snacks like crisps, cakes, biscuits, and sweets. Instead, opt for fresh fruits and vegetables, low-calorie foods, whole grains, and lean protein sources. Regular exercise will also help stabilize your weight and support overall health and well-being.
Pregabid NT Tablet causes sleepiness or drowsiness as a common side effect. Because Pregabid NT Tablet is a tricyclic antidepressant that increases the levels of certain neurotransmitters (serotonin and noradrenaline) in the brain and works by modulating calcium channel activity in nerve cells, which can lead to drowsiness as a side effect, this side effect does not require medical attention and will resolve gradually over time. It's essential to be cautious when engaging in activities that require alertness, such as driving or operating heavy machinery. However, you are advised to talk to your doctor if you experience these side effects persistently.
Taking Pregabid NT Tablet can affect your sexual life. You might experience lower sex drive, erectile dysfunction, or problems with ejaculation or orgasm. If you notice any of these changes, it's important to tell your doctor. They can help you find solutions or adjust your medication to minimize these effects. Remember, being open and honest about your sexual health is crucial in managing potential side effects and finding the best treatment for you.
Most common side effects of Pregabid NT Tablet tend to subside as your body adapts to the medication. However, in rare cases, you may experience severe reactions, including allergic responses, significant mood changes (such as suicidal ideation), seizures, or irregular heartbeats. If you encounter any of these symptoms, seek medical attention immediately. Prompt treatment can help address these issues and ensure your safety. Remember, it's always best to consult with your healthcare provider if you have concerns.
The time it takes for Pregabid NT Tablet to take effect can vary considerably from person to person. While some people may start feeling better after a couple of weeks, it may take up to 4-6 weeks to experience the full benefits. The exact duration of treatment will depend on your individual medical condition, and your doctor will provide personalized guidance on the recommended course of treatment.
If you forget to take Pregabid NT Tablet , take it as soon as you remember. A small variation in time may not show much effect. If it is too late, continue taking the next dose as indicated, But never take a double dose in your next dose. Consult your doctor if you are uncomfortable or experiencing symptoms.
Never use a greater quantity of medicine than prescribed. Pregabid NT Tablet may cause serious side effects such as abnormal heartbeat, seizures, allergic reactions, and suicidal ideation. Please inform your doctor and get medical assistance as soon as possible to avoid major complications.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects and long-term health complications.
While taking Pregabid NT Tablet , it's crucial to be mindful of potential interactions and risks. Avoid excessive alcohol consumption, as it may intensify side effects, and refrain from driving or operating heavy machinery until you understand how the medication affects you. Additionally, consult your doctor before taking other medications or supplements to prevent interactions, and limit grapefruit or grapefruit juice intake, as it may impact absorption. Sudden changes in diet or exercise routines should also be avoided. Furthermore, exercise caution when taking medications containing opioids, as they may interact with Pregabid NT Tablet . By following your doctor's guidance and being aware of these potential interactions, you can minimize risks and ensure the medication works effectively for you.
Regular check-ins with your doctor are crucial when receiving medical treatment to monitor your progress and address any concerns. The frequency of visits may vary depending on your individual situation, but typically, you can expect to see your doctor regularly during the initial treatment phase to adjust treatment plans and monitor side effects. During maintenance, periodic check-ins will also help track your progress and address any concerns.
Storage: Store the Pregabid NT Tablet in its original container to protect it from the external environment. Keep the medication out of reach of children. Store in a cool and dry place away from sunlight.Disposal: Do not consume it after the expiration date.Check the expiration date, remove the label, keep it in a plastic bag, and throw it in household trash. Do not flush the medication down the toilet or sink.
No, Pregabid NT Tablet is not an OTC drug; it cannot be given directly without a registered medical practitioner prescription.
The most common side effects of the Pregabid NT Tablet are blurred vision, dizziness, dry mouth, peripheral oedema (swelling of lower legs and hands), nausea, sleepiness, and weight gain. These side effects may not cause many complications but gradually decrease over time. If you feel any discomfort, contact your doctor; you may get guidance to suppress your discomfort.
Pregabid NT Tablet may interact with antidepressants (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline, citalopram, escitalopram, bupropion), pain killer (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant (gabapentin, phenobarbital, phenytoin, clonazepam, topiramate), anti-anxiety (diazepam, alprazolam), sedative-hypnotics (zolpidem), antihistamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), antiemetic (ondansetron). So, please confirm with your doctor about pre-existing diseases and your present medication. Your doctor will weigh the risks and suggest the medication to avoid drug interactions.
While using Pregabid NT Tablet , following a healthy diet and lifestyle is essential to maximize the medication's effectiveness and minimize potential side effects. Eat a balanced diet rich in whole foods, fruits, vegetables, and whole grains, and stay hydrated by drinking plenty of water. Limit your intake of processed and high-sugar foods, and exercise regularly with activities like walking or light physical activity to maintain overall health. Aim for 7-8 hours of sleep per night to help your body recover and manage stress through relaxation techniques like meditation or deep breathing. Additionally, avoid excessive alcohol consumption and smoking. Following these guidelines and consulting your doctor for personalized advice can optimize your treatment and improve your overall well-being.
The most crucial advice while using any medication is to prioritize your mental health and safety. If you're using a medication that can increase the risk of suicidal thoughts or behaviour, it's essential to be closely monitored by your healthcare provider. If you experience any thoughts or feelings of self-harm, it's vital to seek help immediately. Don't hesitate to reach out to your doctor or a crisis helpline for support. Remember, your well-being is the top priority; timely intervention can make a significant difference.
Pregabid NT Tablet can be taken with or without food. Swallow it as a whole with a glass of water, do not chew or break it. Always follow your physician's instructions for how much and how many doses to take. Also, inform your doctor if you are having any discomfort; they will guide you in managing it.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
There have been no long-term side effects reported as of now. If you experience any side effects that persist, please stop taking the medication and consult the doctor immediately.
Pregabid NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant).
Pregabid NT Tablet should not be given to children as safety and efficacy have not been established. Please reach out to the doctor for more assistance.
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