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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pregabid D 75/20 Capsule is used in the treatment of diabetic neuropathic pain and fibromyalgia. It contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Pregabid D 75/20 Capsule may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation.

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Synonym :

DULOXETINE HYDROCHLORIDE+PREGABALIN

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pregabid D 75/20 Capsule

Pregabid D 75/20 Capsule belongs to an anticonvulsant class of medicines. It is used in the treatment of diabetic neuropathic pain and fibromyalgia. Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged. Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. Fibromyalgia is a chronic condition with moderate pain and tenderness all over the body resulting in fatigue and trouble sleeping.

Pregabid D 75/20 Capsule is a combination of Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Pregabid D 75/20 Capsule can be taken with or without food or as prescribed by your doctor. Pregabid D 75/20 Capsule may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist, inform your doctor.

Pregabid D 75/20 Capsule should be avoided if you are allergic to it. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). If you are pregnant or breastfeeding, inform your doctor before taking this medicine. It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. 

Uses of Pregabid D 75/20 Capsule

Treatment of Diabetic Neuropathic Pain and Fibromyalgia

Directions for Use

Take Pregabid D 75/20 Capsule as prescribed by your doctor. Swallow it as a whole with water. It can be taken with or without food. Do not crush, break or chew it.

Medicinal Benefits

Pregabid D 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Pregabid D 75/20 Capsule effectively treats neuropathic pain, and improves nerve conduction for proper nerve signal functioning in the body. 

How Pregabid D 75/20 Capsule Works

Pregabid D 75/20 Capsule contains Ozenoxacin, a quinolone antibiotic medicine. It works by inhibiting the protein synthesis responsible for bacterial cell growth, thereby killing the bacteria and treating bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pregabid D 75/20 Capsule

  • Burning sensation
  • Drowsiness
  • Nausea
  • Constipation
  • Headache
  • Dry mouth
  • Increased sweating
  • Loss of appetite

What if I have taken an overdose of Pregabid D 75/20 Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Pregabid D 75/20 Capsule may include autonomic instability, blurred vision, coma, confusion, diarrhoea, excessive sleepiness, muscle twitching, numbness, seizures, somnolence, speech disturbances, syncope, tachycardia, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Pregabid D 75/20 Capsule should be avoided if you are allergic to any of the components in it. Do not stop taking Pregabid D 75/20 Capsule suddenly without your doctor’s advice, as it may cause withdrawal symptoms like dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, or glaucoma (an eye condition). Pregabid D 75/20 Capsule may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. It is not recommended for use in children below 18 years of age as the safety and efficacy of this medicine are not established. Pregnant or breastfeeding mothers should inform the doctor before using Pregabid D 75/20 Capsule .

Drug-Drug Interactions

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DuloxetineRasagiline
Critical
DuloxetineSelegiline
Critical

Drug-Drug Interactions

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DuloxetineRasagiline
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking Rasagiline with Pregabid D 75/20 Capsule 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Pregabid D 75/20 Capsule 10's is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking Pregabid D 75/20 Capsule 10's with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Pregabid D 75/20 Capsule 10's and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineLinezolid
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking Pregabid D 75/20 Capsule 10's with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Pregabid D 75/20 Capsule 10's with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineProcarbazine
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking Pregabid D 75/20 Capsule 10's with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregabid D 75/20 Capsule 10's with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Coadministration of safinamide with Pregabid D 75/20 Capsule 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Pregabid D 75/20 Capsule 10's is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineTranylcypromine
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking Tranylcypromine with Pregabid D 75/20 Capsule 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Pregabid D 75/20 Capsule 10's is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetinePhenelzine
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Taking phenelzine with Pregabid D 75/20 Capsule 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregabid D 75/20 Capsule 10's with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Coadministration of metoclopramide with Pregabid D 75/20 Capsule 10's increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Pregabid D 75/20 Capsule 10's is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Coadministration of eliglustat and Pregabid D 75/20 Capsule 10's can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pregabid D 75/20 Capsule 10's with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
PregabalinFentanyl
Severe
How does the drug interact with Pregabid D 75/20 Capsule 10's:
Using Pregabid D 75/20 Capsule 10's together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregabid D 75/20 Capsule 10's can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise regularly, which helps in reducing pain.
  • Rest well, and get enough sleep.
  • Always take a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Pregabid D 75/20 Capsule Substitute

Substitutes safety advice
  • Maxdulin 75 mg/20 mg Capsule 10's

    21.51per tablet
  • Pregaba D 75/20 Capsule 10's

    25.08per tablet
  • Pregeb D 75/20 Capsule 10's

    23.23per tablet
  • Pregalin D 75/20 Capsule 10's

    21.60per tablet
  • Neurokem D 75 mg/20 mg Capsule 10's

    21.42per tablet
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Alcohol

Unsafe

Avoid alcohol consumption during treatment with $nmae as it may increase the risk of serious side effects and worsen your health.

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Pregnancy

Caution

If you are pregnant, especially in the last trimester or planning pregnancy, inform your doctor before taking Pregabid D 75/20 Capsule . It may cause foetal abnormalities if taken in the last trimester of pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking Pregabid D 75/20 Capsule . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Pregabid D 75/20 Capsule may cause drowsiness. Hence, avoid driving vehicles or operating machines after taking Pregabid D 75/20 Capsule .

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Liver

Caution

If you have liver conditions, inform your doctor before taking Pregabid D 75/20 Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney conditions, inform your doctor before taking Pregabid D 75/20 Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Pregabid D 75/20 Capsule is not recommended for children below 18 years as the safety and efficacy of use for this medicine are not established. Please seek medical advice for more information.

FAQs

Pregabid D 75/20 Capsule is used in the treatment of diabetic neuropathic pain and fibromyalgia. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.
Do not stop using Pregabid D 75/20 Capsule suddenly as it can cause withdrawal symptoms. Your doctor will gradually reduce the dose based on your clinical condition.
Seek medical attention immediately if you notice any depressive thoughts while using Pregabid D 75/20 Capsule . Your doctor may change the dose or medicine to treat your condition.
Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged.
Pregabid D 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin is an anticonvulsant drug, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. Both medicines mainly work by increasing the chemical messengers in the brain responsible for regulating pain.
To manage weight gain associated with the use of Pregabid D 75/20 Capsule , maintain a balanced diet and engage in regular exercise. Use the lowest effective dose to help reduce the chances of gaining weight. Keep track of your weight and consult your doctor if you notice significant changes. They can help adjust your treatment or suggest ways to manage your weight more effectively.
Pregabid D 75/20 Capsule may cause sleepiness or drowsiness in some individuals as a mild side effect. If you experience these symptoms, it is important to avoid activities that require full alertness, such as driving or operating machinery. If drowsiness persists for a longer period, please consult your doctor.
Pregabid D 75/20 Capsule may take several weeks or longer to show its full effects. While some patients may notice improvements within the first week, it is important to continue taking the medication as prescribed to achieve the full benefits. Your doctor will likely reduce your dose gradually to avoid withdrawal symptoms.
If you forget to take Pregabid D 75/20 Capsule , take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
No, taking a higher dose of Pregabid D 75/20 Capsule than recommended will not necessarily make it more effective and may increase the risk of side effects. Additionally, it can become habit-forming if misused or taken in larger amounts than prescribed for a prolonged period, leading to dependence. If you feel your current dose is not effective, please consult your doctor for proper adjustments, rather than increasing the dose on your own.
It is not recommended to drink alcohol while taking Pregabid D 75/20 Capsule , as it may increase the risk of side effects such as drowsiness and dizziness. These effects impair your ability to perform tasks that require focus, so avoid driving or operating machinery while taking Pregabid D 75/20 Capsule . Always consult your doctor for personalized advice.
Pregabid D 75/20 Capsule should typically be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.
Pregabid D 75/20 Capsule may cause common side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please inform your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PRE1519

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