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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Praxbind 2.5gm/50ml Solution For Injection is used in the treatment of severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots). It contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran to inactivate its effect. Common side effects of Praxbind 2.5gm/50ml Solution For Injection are headaches, constipation, fever, low potassium levels, and confusion.

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Praxbind 2.5gm/50ml Solution For Injection

Praxbind 2.5gm/50ml Solution For Injection belongs to the group of medicines called anticoagulant reversal agents used during a medical emergency to treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).

Praxbind 2.5gm/50ml Solution For Injection contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.

Praxbind 2.5gm/50ml Solution For Injection will be administered by a healthcare professional; do not self-administer. In some cases, Praxbind 2.5gm/50ml Solution For Injection may cause headaches, constipation, fever, low potassium levels, and confusion. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and effectiveness of Praxbind 2.5gm/50ml Solution For Injection in children have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Praxbind 2.5gm/50ml Solution For Injection

Treatment of severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots)

Medicinal Benefits

Praxbind 2.5gm/50ml Solution For Injection belongs to the group of medicines called anticoagulant reversal agents indicated in patients treated with dabigatran (a medicine used to prevent blood clots) when reversal of the anticoagulant effects of dabigatran is needed for emergency surgery/urgent procedures, in life-threatening conditions or uncontrolled bleeding. Praxbind 2.5gm/50ml Solution For Injection contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.

Directions for Use

Praxbind 2.5gm/50ml Solution For Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Praxbind 2.5gm/50ml Solution For Injection

  • Headache
  • Constipation
  • Fever
  • Hypokalaemia (low potassium levels)
  • Confusion

Drug Warnings

Inform the doctor if you are allergic to any of the components in Praxbind 2.5gm/50ml Solution For Injection, if you have hereditary fructose intolerance or if you are on a sodium-restricted diet. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking monoclonal antibodies (rozanolixizumab, efgartigimod alfa).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have fructose intolerance or liver impairment.

Drug-Drug Interactions Checker List

  • ROZANOLIXIZUMAB
  • EFGARTIGIMOD ALFA

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Disease/Condition Glossary

Bleeding: Bleeding is the loss of blood inside or outside the body. It is the main risk associated with dabigatran treatment. Severe or uncontrolled bleeding requires immediate medical attention to prevent loss of blood. Anticoagulant reversal agents such as Praxbind 2.5gm/50ml Solution For Injection are used to treat severe and uncontrolled bleeding.

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Alcohol

Consult your doctor

It is not known if alcohol affects Praxbind 2.5gm/50ml Solution For Injection. Please consult your doctor.

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Pregnancy

Caution

Praxbind 2.5gm/50ml Solution For Injection should be given to pregnant women only if clearly needed. Inform the doctor if you are pregnant or think you may be pregnant.

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Breast Feeding

Caution

Caution is advised while administering Praxbind 2.5gm/50ml Solution For Injection to a nursing woman.

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Driving

Not applicable

This medicine is for hospital use only.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Praxbind 2.5gm/50ml Solution For Injection.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Praxbind 2.5gm/50ml Solution For Injection.

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Children

Caution

The safety and effectiveness of Praxbind 2.5gm/50ml Solution For Injection in children have not been established.

Country of origin

India

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11Th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - PRA0330

Author Details

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FAQs

Praxbind 2.5gm/50ml Solution For Injection is used to treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).
Praxbind 2.5gm/50ml Solution For Injection rapidly traps dabigatran in order to inactivate its effect.
Praxbind 2.5gm/50ml Solution For Injection may contain sorbitol, which can cause serious or life-threatening metabolic problems in people with hereditary fructose intolerance (a genetic disorder). Therefore, inform the doctor if you have hereditary fructose intolerance.
Praxbind 2.5gm/50ml Solution For Injection does not remove other medicines used to prevent the formation of blood clots. It will only remove dabigatran from your body.

Disclaimer

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Keep Refrigerated. Do not freeze.

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