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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Pradaxa 150 mg Capsule is an anticoagulant medicine used to prevent blood clot formation. This medicine prevents/treat conditions like deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), heart attack, and stroke. This medicine works by inhibiting the production of clotting factor Xa, also called thrombin. thereby preventing the conversion of fibrinogen to fibrin, a protein that helps prevent blood clot formation. Common side effects include bleeding, anaemia, nausea, stomach pain, and vomiting.
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Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pradaxa 150 mg Capsule

Pradaxa 150 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Pradaxa 150 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Pradaxa 150 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Pradaxa 150 mg Capsule as prescribed by your doctor. You are advised to take Pradaxa 150 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Pradaxa 150 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Pradaxa 150 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 150 mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 150 mg Capsule . Try not to stop taking this medicine on your own. Discontinuing Pradaxa 150 mg Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Pradaxa 150 mg Capsule

Prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Pradaxa 150 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Pradaxa 150 mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Pradaxa 150 mg Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Pradaxa 150 mg Capsule Works

Pradaxa 150 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Pradaxa 150 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pradaxa 150 mg Capsule

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

What if I have taken an overdose of Pradaxa 150 mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Pradaxa 150 mg Capsule may include an increase in the risk of bleeding. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are known to be allergic to Pradaxa 150 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 150 mg Capsule . Pradaxa 150 mg Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 150 mg Capsule . You should inform the doctor that you are taking Pradaxa 150 mg Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Pradaxa 150 mg Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilatePrimidone
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Pradaxa 150 mg Capsule:
When Mifepristone is taken with Pradaxa 150 mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Pradaxa 150 mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePrimidone
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Primidone can increase the risk of bleeding.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateKetoconazole
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Coadministration of Ketoconazole and Pradaxa 150 mg Capsule may increase the blood levels and effects Pradaxa 150 mg Capsule. This may increase the risk of anemia and bleeding issues.

How to manage the interaction:
Although taking Ketoconazole and Pradaxa 150 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice paleness, exhaustion, dizziness, fainting, unusual bleeding or bruising, swelling, nausea, vomiting, blood in your urine or stools, headache, or weakness, consult a doctor. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateRivaroxaban
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Co-administration of Pradaxa 150 mg Capsule and Rivaroxaban can increase the risk of bleeding, including severe blood loss.

How to manage the interaction:
Co-administration of Pradaxa 150 mg Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding, dizziness, tarry stools, coughing up or vomiting blood, or severe headache, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateArgatroban
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Argatroban can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Argatroban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateBivalirudin
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Bivalirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Bivalirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDeferasirox
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Combining Pradaxa 150 mg Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Pradaxa 150 mg Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateRegorafenib
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Regorafenib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Regorafenib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateFenoprofen
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Fenoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Fenoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateAlteplase
Severe
How does the drug interact with Pradaxa 150 mg Capsule:
Taking Pradaxa 150 mg Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 150 mg Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Pradaxa 150 mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Pradaxa 150 mg Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Pradaxa 150 mg Capsule Substitute

Substitutes safety advice
  • Dabiclot 150 Capsule 10's

    by AYUR

    35.87per tablet
  • Dablexa 150 Capsule 10's

    by AYUR

    35.87per tablet
  • Afogatran 150 Capsule 10's

    by AYUR

    35.82per tablet
  • Dabigza 150 Capsule 14's

    by Others

    29.70per tablet
  • Dabifib 150 mg Capsule 10's

    by AYUR

    27.15per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Pradaxa 150 mg Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Pradaxa 150 mg Capsule . Your doctor will prescribe Pradaxa 150 mg Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Pradaxa 150 mg Capsule . Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Pradaxa 150 mg Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 150 mg Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 150 mg Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Pradaxa 150 mg Capsule is not recommended for children below the age of 18 years as the safety and efficacy of Pradaxa 150 mg Capsule have not been established in children.

FAQs

Pradaxa 150 mg Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Pradaxa 150 mg Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Pradaxa 150 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Pradaxa 150 mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Pradaxa 150 mg Capsule .

Pradaxa 150 mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Pradaxa 150 mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Pradaxa 150 mg Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Pradaxa 150 mg Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Pradaxa 150 mg Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Pradaxa 150 mg Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Pradaxa 150 mg Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Pradaxa 150 mg Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 150 mg Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Pradaxa 150 mg Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Pradaxa 150 mg Capsule treatment; patients should be monitored for signs of bleeding.

Pradaxa 150 mg Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 150 mg Capsule .

Common side effects of Pradaxa 150 mg Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

Germany

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - PRA0178

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