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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Plurasund Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough and also sometimes to relieve allergic symptoms. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing and thus reduce cough. Some people may experience side effects like dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Desun Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Plurasund Syrup

Plurasund Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Plurasund Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.

Take Plurasund Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Plurasund Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Plurasund Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please inform your doctor if you are allergic to Plurasund Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Plurasund Syrup . Plurasund Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Plurasund Syrup . Avoid using Plurasund Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Plurasund Syrup to loosen mucus.

Uses of Plurasund Syrup

Treatment of Dry Cough

Medicinal Benefits

Plurasund Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, Plurasund Syrup helps to relieve overall cough, cold and allergic symptoms.

Directions for Use

Shake the bottle well before use. Check the label for directions and take Plurasund Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Plurasund Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

Please inform your doctor if you are allergic to Plurasund Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Plurasund Syrup . Plurasund Syrup is not recommended for children below 4 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Plurasund Syrup . Avoid using Plurasund Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Plurasund Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Plurasund Syrup .

Drug Interactions

Drug-Drug Interaction: Plurasund Syrup may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interaction: Plurasund Syrup may interact with alcohol. Therefore, avoid alcohol consumption with Plurasund Syrup as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: Plurasund Syrup is known to interact in patients with liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. 
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Special Advise

  • Do not use Plurasund Syrup only to make a child sleepy. 
  • Contact a doctor if your symptoms do not improve even after 7 days.
  • Contact a doctor immediately if you develop fever, rash or headaches after taking Plurasund Syrup . 

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants from the airways (such as allergens, mucus, or smoke) and preventing infection. Coughs can be productive or dry. A productive cough (wet cough) causes sputum (phlegm, mucus, and other matter) to be expelled from the lungs. Coughing is commonly caused by an allergic reaction or a viral infection, but coughing up mucus could indicate a respiratory infection. You may have a bacterial infection in your airways if you cough up thick, solid white mucus. If your mucus is clear or light-coloured, you may have allergies or minor respiratory infections, whereas yellow or green mucus indicates a respiratory infection.

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Alcohol

Caution

Avoid consumption of alcohol with Plurasund Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Plurasund Syrup .

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Pregnancy

Caution

The safety of Plurasund Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Plurasund Syrup is excreted in human milk. Plurasund Syrup is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Plurasund Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Plurasund Syrup .

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Liver

Caution

Take Plurasund Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Plurasund Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Plurasund Syrup is not recommended for children below 4 years of age. However, please consult a doctor before using Plurasund Syrup in children.

Country of origin

INDIA

Manufacturer/Marketer address

s 16, kasba industrial estate, phase iii, east kolkata township, kolkata - 700107
Other Info - PLU0029

Author Details

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FAQs

Plurasund Syrup belongs to a class of medication called 'cough and cold preparations primarily used to treat dry cough. Coughing (dry or productive) is the body way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection.
Plurasund Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
No, you should not take Plurasund Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Therefore, if you are about to undergo any surgery, please inform your doctor that you are taking Plurasund Syrup . Your doctor may advise you to stop taking Plurasund Syrup 72 hours before the surgery.
It is not recommended to take Plurasund Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Plurasund Syrup should be taken at least 15 days after your last dose of anti-depressants.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Plurasund Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.
Plurasund Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma, as Plurasund Syrup may rarely worsen the symptoms of glaucoma.

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