Pletoz-100 Tablet consists of the anti-platelet drug (blood thinner) primarily used to treat intermittent claudication (pain, tingling, and numbness in the legs). Intermittent claudication is the pain that occurs in the legs after walking at a specific speed and for a specific amount of time, depending on the seriousness of the condition. This pain generally is not constant. It occurs during walking and exercise and is relieved with rest.

Pletoz-100 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Pletoz-100 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. Pletoz-100 Tablet works by expanding the veins and reducing the stickiness of the platelets. Therefore, enhancing the blood flow to the lower limbs.

Take Pletoz-100 Tablet as prescribed by your doctor. You are advised to take Pletoz-100 Tablet as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience headache, dizziness, diarrhoea, abnormal stool, palpitations (racing or skipping a heartbeat), chest pain, bleeding, loss of appetite, and rashes. Most of these side effects of Pletoz-100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Pletoz-100 Tablet or any of its components, please tell your doctor. Pletoz-100 Tablet should not be taken in pregnant, planning to become pregnant, or breastfeeding women. Pletoz-100 Tablet should not be given to people with a bleeding disorder (haemophilia). Pletoz-100 Tablet may cause drowsiness and dizziness, so it is advisable to avoid driving unless you are alert. Pletoz-100 Tablet is not recommended for use in children.

Pletoz-100 Tablet plays a vital role in preventing the formation of harmful blood clots in your veins by making platelets (clotting agents) stick together. Pletoz-100 Tablet is used to decrease the symptoms of intermittent claudication (pain in the legs that develops when walking and improves when resting that is produced by narrowing of the vein that supplies blood to the legs). Pletoz-100 Tablet works by expanding the veins and reducing the stickiness of the platelets. Therefore, it enhances the blood flow to the legs.

• Headache
• Dizziness
• Diarrhea
• Abnormal stool
• Palpitations (racing or skipping a heartbeat)
• Chest pain
• Bleeding
• Loss of appetite
• Rashes

If you are known to be allergic to Pletoz-100 Tablet or any of its components, please tell your doctor. Prolonged use of Pletoz-100 Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising). If you are going to have any surgery, discontinue taking Pletoz-100 Tablet before the surgery. Pletoz-100 Tablet should not be taken in the conditions like heart failure, chest pain, heart attack, and heart surgery. Pletoz-100 Tablet should not be taken if you have an increased risk of bleeding like stomach ulcers, stroke, or problems with your eyes if you have diabetes. Before taking Pletoz-100 Tablet inform your doctor if your blood pressure is not well controlled. Pletoz-100 Tablet should not be taken in conditions if you have severe kidney disease. Pletoz-100 Tablet should not be taken in pregnant, planning to become pregnant, or breastfeeding women. Pletoz-100 Tablet should be not given to people with a bleeding disorder (hemophilia). Pletoz-100 Tablet may cause drowsiness and dizziness it is advisable to avoid driving unless you are alert. Pletoz-100 Tablet is not recommended for use in children.

Drug-Drug Interaction: Pletoz-100 Tablet may have interaction with other blood thinners (aspirin, clopidogrel, warfarin), antibiotics (erythromycin, clarithromycin, rifampicin), fungal infections medicines (ketoconazole), antacid (omeprazole), blood-pressure-lowering medicines (diltiazem), cholesterol-lowering medicines (lovastatin, simvastatin or atorvastatin), medicines for malaria (halofantrine), medicines for mental illness (pimozide), medicines used for migraine (ergotamine, dihydroergotamine), water pills (hydrochlorothiazide, furosemide).

Drug-Food Interaction: Pletoz-100 Tablet may interact with a large amount of grapefruit juice and St John’s wort plant (used as an antidepressant).

Drug-Disease Interaction:  Pletoz-100 Tablet should not be given to people with a bleeding disorder, liver disease, and heart disease.

• ASPIRIN
• CLOPIDOGREL
• WARFARIN
• ERYTHROMYCIN
• CLARITHROMYCIN
• RIFAMPICIN
• KETOCONAZOLE
• OMEPRAZOLE
• DILTIAZEM
• LOVASTATIN
• SIMVASTATIN
• ATORVASTATIN
• HALOFANTRINE
• PIMOZIDE
• ERGOTAMINE
• DIHYDROERGOTAMINE
• HYDROCHLOROTHIAZIDE
• FUROSEMIDE

• As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to a freshly prepared home-cooked meal, and take proper rest, for a speedy recovery.

• Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it is beneficial to eat them regularly.

• Take Pletoz-100 Tablet at least half an hour before or two hours after breakfast and dinner.

Intermittent claudication is the pain that occurs in the legs after walking at a specific speed and for a specific amount of time, depending on the seriousness of the condition. This pain generally is not constant. It occurs during walking and exercise and is relieved with rest. In this disease, muscles of the leg do not get enough blood while you exercise. Sometimes, it causes complications like pain occurs even when you are not exercising.