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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Plaqstat ASP 20 mg/75 mg Capsule is used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body. It contains Rosuvastatin and Aspirin, which lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Also, it decreases the formation of blood clots by preventing the platelets from clubbing together. It may cause common side effects such as increased bleeding tendency, nausea, abdominal pain, headache, constipation, muscle pain, weakness, dizziness and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Metabolica Lifecare Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Plaqstat ASP 20 mg/75 mg Capsule

Plaqstat ASP 20 mg/75 mg Capsule is a combination of blood-thinning agent and cholesterol-lowering agent, primarily used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). 

Plaqstat ASP 20 mg/75 mg Capsule is composed of two medicines, namely: Rosuvastatin and Aspirin. Rosuvastatin belongs to the class of antilipemic (cholesterol-lowering) agents. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It decreases the formation of blood clots by preventing the platelets from clubbing together. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Plaqstat ASP 20 mg/75 mg Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases. 

Your doctor will advise you how often you take your tablets based on your medical condition. The common side effects of Plaqstat ASP 20 mg/75 mg Capsule include increased bleeding tendency, nausea, abdominal pain, headache, constipation, muscle pain, weakness, dizziness and indigestion. These side effects do not occur in everyone using Plaqstat ASP 20 mg/75 mg Capsule and may vary individually. If these side effects occur, they resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine of your own. Stopping Plaqstat ASP 20 mg/75 mg Capsule may worsen your condition and increase the risk of a future heart attack. Let your doctor know if you are sensitive to rosuvastatin or aspirin and have any kidney/liver diseases, asthma, active bleeding issues (like peptic ulcer, brain haemorrhage), gastrointestinal disorders, diabetes, mental illnesses (memory loss, forgetfulness, amnesia, memory impairment, confusion), and musculoskeletal disorders before starting Plaqstat ASP 20 mg/75 mg Capsule . If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Plaqstat ASP 20 mg/75 mg Capsule . The patient should inform the doctor if he/she is taking Plaqstat ASP 20 mg/75 mg Capsule before any surgery is scheduled or any new medicine is taken.

Uses of Plaqstat ASP 20 mg/75 mg Capsule

Treatment of Myocardial infarction (Heart attack) and Stroke.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Plaqstat ASP 20 mg/75 mg Capsule is composed of Rosuvastatin and Aspirin. Rosuvastatin is an antilipemic agent (cholesterol-lowering) or HMG-CoA reductase inhibitor. It works by blocking liver enzymes, causing the liver to make less cholesterol. It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Rosuvastatin reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). Aspirin is a non-steroidal anti-inflammatory (NSAID) and anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together. It is also used in heart-related revascularization procedures (provision of new blood supply to a body part), such as coronary artery bypass graft to improve the blood flow through the revascularized area. Plaqstat ASP 20 mg/75 mg Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.

How Plaqstat ASP 20 mg/75 mg Capsule Works

Plaqstat ASP 20 mg/75 mg Capsule is composed of two medicines, namely: Rosuvastatin and Aspirin. Rosuvastatin belongs to the class of antilipemic (cholesterol-lowering) agents. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It decreases the formation of blood clots by preventing the platelets from clubbing together. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Plaqstat ASP 20 mg/75 mg Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Plaqstat ASP 20 mg/75 mg Capsule

  • Nausea
  • Abdominal Pain
  • Headache
  • Constipation
  • Muscle Pain
  • Weakness
  • Dizziness
  • Increased Bleeding Tendency
  • Indigestion

What if I have taken an overdose of Plaqstat ASP 20 mg/75 mg Capsule

Do not take more than the prescribed dose of Plaqstat ASP 20 mg/75 mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Before taking Plaqstat ASP 20 mg/75 mg Capsule , let your doctor know if you have a history of liver and kidney diseases or allergic reactions to aspirin and rosuvastatin. If you are at risk of internal bleeding (bleeding inside any tissues, organs or joints of your body), a recent injury/surgery or a planned surgery (including dental) in the next few days, coagulation disorders, such as haemophilia and thrombocytopenia and active bleeding issues (peptic ulcer, brain haemorrhage), please inform your doctor before starting the medicine. If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Plaqstat ASP 20 mg/75 mg Capsule . Do not drive or operate machinery if you experience dizziness or drowsiness while using Plaqstat ASP 20 mg/75 mg Capsule . Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. Plaqstat ASP 20 mg/75 mg Capsule is not recommended for children below the age of 16 years. 

Drug-Drug Interactions

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AspirinKetorolac tromethamine
Critical
AspirinKetorolac
Critical

Drug-Drug Interactions

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AspirinKetorolac tromethamine
Critical
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Combining Ketorolac tromethamine with Plaqstat ASP 20 mg/75 mg Capsule 10's can increase the risk of adverse effects.

How to manage the interaction:
Taking Plaqstat ASP 20 mg/75 mg Capsule 10's with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Co-administration of Ketorolac and Plaqstat ASP 20 mg/75 mg Capsule 10's may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Plaqstat ASP 20 mg/75 mg Capsule 10's is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AspirinDrotrecogin alfa (activated)
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Coadministration of Plaqstat ASP 20 mg/75 mg Capsule 10's and Drotrecogin alfa may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Drotrecogin alfa (activated) and Plaqstat ASP 20 mg/75 mg Capsule 10's, but it can be taken if prescribed by a doctor. It's important to keep a close eye on any signs of bleeding and let a doctor know right away if you experience any of these symptoms - close monitoring or bleeding. Do not stop using any medications without a doctor's advice.
AspirinPonatinib
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Using Ponatinib together with Plaqstat ASP 20 mg/75 mg Capsule 10's may increase the risk of bleeding.

How to manage the interaction:
Taking Ponatinib with Plaqstat ASP 20 mg/75 mg Capsule 10's together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without talking to a doctor.
AspirinEdoxaban
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
When edoxaban is used with Plaqstat ASP 20 mg/75 mg Capsule 10's, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule 10's and edoxaban, you can take these medicines together if prescribed by a doctor. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without consulting a doctor.
AspirinDicoumarol
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Using warfarin together with Dicoumarol may cause you to bleed more easily.

How to manage the interaction:
Taking Plaqstat ASP 20 mg/75 mg Capsule 10's with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any bleeding, it's important to contact a doctor right away. They will be able to help you and provide the necessary care. Do not discontinue any medications without consulting a doctor.
AspirinEnoxaparin
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Using enoxaparin along with Plaqstat ASP 20 mg/75 mg Capsule 10's, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule 10's and enoxaparin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinDesirudin
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Using Desirudin together with Plaqstat ASP 20 mg/75 mg Capsule 10's may increase the risk of bleeding.

How to manage the interaction:
Taking Plaqstat ASP 20 mg/75 mg Capsule 10's with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, serious bleeding, complications, bleeding, bruising, feeling dizzy or lightheaded, dark or tar-like stools, intense headache, weakness, bleeding, or vomiting. Do not stop using any medications without talking to a doctor.
AspirinDasatinib
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Coadministration of Dasatinib with Plaqstat ASP 20 mg/75 mg Capsule 10's may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Plaqstat ASP 20 mg/75 mg Capsule 10's and Dasatinib, you can take these medicines together if prescribed by a doctor. However, if you notice bruising, swelling, vomiting, headache, dizziness, or weakness inform a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinTeriflunomide
Severe
How does the drug interact with Plaqstat ASP 20 mg/75 mg Capsule 10's:
Coadministration of Plaqstat ASP 20 mg/75 mg Capsule 10's and Teriflunomide can enhance the risk of liver problems.

How to manage the interaction:
Although co-administration of Plaqstat ASP 20 mg/75 mg Capsule 10's with teriflunomide can lead to an interaction, it can be taken if recommended by a doctor. If you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Plaqstat ASP 20 mg/75 mg Capsule .

  • Low cholesterol diet and regular exercise regime are found to complement treatment with Plaqstat ASP 20 mg/75 mg Capsule effectively. 

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.

  • The high-fat meal should be avoided as it may further increase the risk of a heart attack instead of eating heart-healthy foods.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on noticing and managing the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Plaqstat ASP 20 mg/75 mg Capsule Substitute

Substitutes safety advice
  • Rozucor ASP-20 Capsule 10's

    by AYUR

    15.17per tablet
  • Roseday A 20 Capsule 10's

    by AYUR

    12.56per tablet
  • Unistar 20/75mg Capsule 10's

    13.19per tablet
  • Statpure-A 20 mg/75 mg Capsule 15's

    10.68per tablet
  • Novastat-ASP Capsule 10's

    11.70per tablet
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increase blood pressure.

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Pregnancy

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is unsafe to use during pregnancy since it has harmful effects on the foetus. If the patient becomes pregnant while using Plaqstat ASP 20 mg/75 mg Capsule , please discontinue immediately, and you should be aware of the potential risks to the foetus. Please consult your doctor if you are planning to conceive or are already pregnant before starting Plaqstat ASP 20 mg/75 mg Capsule .

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Breast Feeding

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is not recommended for use if you are a lactating mother since it may affect the breastfed infant. Please consult your doctor before starting Plaqstat ASP 20 mg/75 mg Capsule .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Plaqstat ASP 20 mg/75 mg Capsule . Plaqstat ASP 20 mg/75 mg Capsule can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Plaqstat ASP 20 mg/75 mg Capsule .

bannner image

Children

Unsafe

Plaqstat ASP 20 mg/75 mg Capsule is not recommended for children below the age of 16 years. The safety and efficacy of Plaqstat ASP 20 mg/75 mg Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

FAQs

Plaqstat ASP 20 mg/75 mg Capsule is primarily used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body.
Plaqstat ASP 20 mg/75 mg Capsule consists of Rosuvastatin and Aspirin. Rosuvastatin works by blocking liver enzymes, causing the liver to make less cholesterol. It lowers the bad cholesterol levels and increases good cholesterol levels in the blood, thus preventing heart attack and stroke. Aspirin is a non-steroidal anti-inflammatory (NSAID) and anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together, which is the primary cause for heart attack and stroke.
Plaqstat ASP 20 mg/75 mg Capsule consists of Aspirin. It is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.
Please consult your doctor if Plaqstat ASP 20 mg/75 mg Capsule needs to be discontinued before undergoing a dental procedure or any surgery. The doctor might ask you to stop taking Plaqstat ASP 20 mg/75 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.
Brief your medical history to your doctor if you have any kidney/liver diseases, asthma, active bleeding issues (like peptic ulcer, brain haemorrhage), gastrointestinal disorders, diabetes, musculoskeletal disorder and mental illness before taking Plaqstat ASP 20 mg/75 mg Capsule .
Plaqstat ASP 20 mg/75 mg Capsule can cause dizziness as one of its side effects. Please consult your doctor if you feel dizzy for a longer time. Avoid driving or operating machinery during episodes of dizziness.
Plaqstat ASP 20 mg/75 mg Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting stomach pain, heartburn or constipation, your doctor may prescribe a medicine to treat such side effects, while you're taking Plaqstat ASP 20 mg/75 mg Capsule .
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Swallow the medicine as a whole with water; do not crush, break or chew it. Your doctor will advise you how often you take your tablets based on your medical condition.
Before taking the Plaqstat ASP 20 mg/75 mg Capsule , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Low cholesterol diet and regular exercise regime are found to complement treatment with Plaqstat ASP 20 mg/75 mg Capsule effectively.
Yes, in cases, using Plaqstat ASP 20 mg/75 mg Capsule may lead to unexplained muscle pain, tenderness, weakness or cramps. his can happen a few weeks or months after you first start taking this medicine. Contact your doctor if your symptoms continue for more than a few days or get worse.
Adopt a heart-healthy diet, exercise regularly, and avoid smoking and excessive alcohol use to improve drug efficacy and lower cardiovascular risk.
Avoid the use of other painkillers while taking Plaqstat ASP 20 mg/75 mg Capsule . If required, your doctor may suggest paracetamol for relieving pain.
It could be beneficial to take your Plaqstat ASP 20 mg/75 mg Capsule after a meal or snack Keep your meals simple and avoid rich or spicy foods. If your symptoms persist or worsen, see your doctor. Make sure you get enough of rest and drinks.
Plaqstat ASP 20 mg/75 mg Capsule may interact with various medications. Tell your doctor about the medicines you need to take. Your doctor will check the interactions and guide you on how to take them.
Store in a cool and dry place away from sunlight. Keep Plaqstat ASP 20 mg/75 mg Capsule out of sight and reach of children. A medicine take-back program is the best approach to properly dispose of your medicines. To learn about community, take-back initiatives, speak with your pharmacist or contact your local garbage/recycling department.
Plaqstat ASP 20 mg/75 mg Capsule is composed of two medicines, namely: Rosuvastatin (cholesterol-lowering agents) and Aspirin (a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action).

Country of origin

India

Manufacturer/Marketer address

Plot No-22, Pratham Society, Near Telephone Exchange Wakad Chinchwad Pune Pune Mh 411057 In
Other Info - PLA0464

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