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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Plagerine-A 150 Capsule is used for the prevention of heart attack and stroke. It contains Aspirin and Clopidogrel, which prevent the formation of a clot in the blood vessels. It helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs). It may cause common side effects such as abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Plagerine-A 150 Capsule

Plagerine-A 150 Capsule is used for the prevention of heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Plagerine-A 150 Capsule is composed of two medicines: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Plagerine-A 150 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs).

Your doctor will advise you on how often you take your tablets based on your medical condition. The common side effects of Plagerine-A 150 Capsule include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Plagerine-A 150 Capsule is known to cause dizziness and blurry vision, so driving should be avoided. Most of these side effects of Plagerine-A 150 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Plagerine-A 150 Capsule may worsen your condition and increase the risk of a future heart attack. Let your doctor know if you are sensitive to clopidogrel or aspirin, have kidney/liver diseases, have bleeding issues (like peptic ulcer or brain haemorrhage), are pregnant or are planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Plagerine-A 150 Capsule before any surgery is scheduled or any new medicine is taken.

Uses of Plagerine-A 150 Capsule

Prevention of heart attack and stroke.

Directions for Use

Swallow Plagerine-A 150 Capsule as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Plagerine-A 150 Capsule is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Plagerine-A 150 Capsule helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of the lungs).

How Plagerine-A 150 Capsule Works

Plagerine-A 150 Capsule is composed of two medicines: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Plagerine-A 150 Capsule

  • Abdominal pain

  • Indigestion

  • Diarrhoea

  • Easy bruising

  • Nosebleeds

  • Increased bleeding tendency

What if I have taken an overdose of Plagerine-A 150 Capsule

Do not take more than the prescribed dose of Plagerine-A 150 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Plagerine-A 150 Capsule if you are allergic to Plagerine-A 150 Capsule . Let your doctor know if you have a medical condition that is causing bleeding such as a haemophilia, stomach ulcer or bleeding within your head or bowel. Caution is required before giving Plagerine-A 150 Capsule to the liver or kidney problems patients. People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of Plagerine-A 150 Capsule . Plagerine-A 150 Capsule is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness of Plagerine-A 150 Capsule in children less than 12 years of age have not been established. 

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
ClopidogrelMifepristone
Critical

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
How does the drug interact with Plagerine-A 150 Capsule 10's:
When Selexipag and Plagerine-A 150 Capsule 10's are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Plagerine-A 150 Capsule 10's with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelMifepristone
Critical
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking Plagerine-A 150 Capsule 10's together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Plagerine-A 150 Capsule 10's with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
AspirinKetorolac
Critical
How does the drug interact with Plagerine-A 150 Capsule 10's:
Co-administration of Ketorolac and Plagerine-A 150 Capsule 10's may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Plagerine-A 150 Capsule 10's is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Plagerine-A 150 Capsule 10's:
Combining Ketorolac tromethamine with Plagerine-A 150 Capsule 10's can increase the risk of adverse effects.

How to manage the interaction:
Taking Plagerine-A 150 Capsule 10's with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
ClopidogrelProtamine
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking Protamine with Plagerine-A 150 Capsule 10's can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Plagerine-A 150 Capsule 10's together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelDabigatran etexilate
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking Plagerine-A 150 Capsule 10's with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between Plagerine-A 150 Capsule 10's and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
ClopidogrelApixaban
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Coadministration of Plagerine-A 150 Capsule 10's and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Plagerine-A 150 Capsule 10's and Apixaban, it can be taken if prescribed by a doctor. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), bruising, dizziness, lightheadedness, or headache. Do not discontinue any medications without consulting a doctor
ClopidogrelDeferasirox
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking deferasirox together with Plagerine-A 150 Capsule 10's may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although taking Plagerine-A 150 Capsule 10's together with Deferasirox has a possibility of interaction, it can be taken if prescribed by your doctor. However, if you experience abdominal pain, bloating, dizziness, lightheadedness, red or black, tarry stools oe headache. Do not discontinue any medication without consulting your doctor.
ClopidogrelRabeprazole
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking Plagerine-A 150 Capsule 10's with Rabeprazole can reduce the effectiveness of Plagerine-A 150 Capsule 10's.

How to manage the interaction:
Taking Plagerine-A 150 Capsule 10's and Rabeprazole together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ClopidogrelLoperamide
Severe
How does the drug interact with Plagerine-A 150 Capsule 10's:
Taking loperamide with Plagerine-A 150 Capsule 10's may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Plagerine-A 150 Capsule 10's with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Plagerine-A 150 Capsule .

  • Keep your cholesterol and triglyceride levels under control.

  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, and vegetables.

  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

  • Keep a check on your weight and exercise regularly to keep your heart healthy.

  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Plagerine-A 150 Capsule Substitute

Substitutes safety advice
  • Clopitab A 150 Capsule 15's

    7.32per tablet
  • Deplatt A 150 Tablet 15's

    6.54per tablet
  • Clopilet A 150 Capsule 15's

    6.12per tablet
  • Clopivas AP 150 Tablet 15's

    6.27per tablet
  • Ceruvin AF Capsule 15's

    6.12per tablet
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Alcohol

Caution

Avoid consuming alcohol since it may worsen the side effects like dizziness and increased blood pressure.

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Pregnancy

Caution

Plagerine-A 150 Capsule is not recommended to use during pregnancy since it may affect the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Plagerine-A 150 Capsule .

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Breast Feeding

Caution

There is limited data on how Plagerine-A 150 Capsule affects breastfeeding. Please consult your doctor before starting Plagerine-A 150 Capsule .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Plagerine-A 150 Capsule . Plagerine-A 150 Capsule can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Plagerine-A 150 Capsule .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Plagerine-A 150 Capsule .

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Children

Caution

Plagerine-A 150 Capsule is not recommended for children below the age of 16 years. The safety and efficacy of Plagerine-A 150 Capsule have not been established in children.

FAQs

Plagerine-A 150 Capsule is used for the prevention of heart attack and stroke.
Plagerine-A 150 Capsule consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).
Please consult your doctor if Plagerine-A 150 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Plagerine-A 150 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.
Plagerine-A 150 Capsule consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.
Plagerine-A 150 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking Plagerine-A 150 Capsule .
Inform your doctor if you suffer from any underlying health conditions such as ulcers, bleeding disorders, stomach swelling, gout, kidney disease, breathing difficulty or asthma that was induced by a painkiller. Also, tell your doctor about all the medications and herbal products you are taking or will soon be taking. Specifically, make sure to mention if you use blood thinners such as aspirin, warfarin and other nonsteroidal anti-inflammatory drugs such as naproxen, as your doctor may need to adjust the dose of your medication or monitor for side effects.
Before undergoing any surgeries or during medical emergencies, inform your doctor that you are taking aspirin, as too much aspirin may result in bleeding disorders.
Take Plagerine-A 150 Capsule as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, break or chew it.
Plagerine-A 150 Capsule should be used as advised by the doctor for best results and do not discontinue Plagerine-A 150 Capsule on your own without consulting your doctor. Following cardiac bypass surgery, recovery takes time and each person recovers at a slightly different pace.
You may have been prescribed Plagerine-A 150 Capsule if you underwent coronary artery bypass graft surgery (CABG), had heart attack, or received treatment with stents in your coronary arteries.
Yes, Plagerine-A 150 Capsule is a blood thinner. It works by preventing the formation of a clot in the blood vessels. Thus, it helps to prevent heart attack and stroke.
Take Plagerine-A 150 Capsule for as long as it is advised by your doctor. The duration depends on various factors such as type of stent inserted, the illness you are being treated for, any episodes of bleeding experienced by you during treatment, etc. Usually, Plagerine-A 150 Capsule is prescribed for a minimum of one year. However, for best results, follow your doctor’s instructions. Do not discontinue on your own without consulting doctor as it may increase the risk of clot formation in the stent, heart attack, and can even lead to death.
You are advised to avoid alcohol consumption while taking Plagerine-A 150 Capsule as it may increase the risk of stomach bleeding. However, if you have any concerns, please discuss with your doctor.
Plagerine-A 150 Capsule may result in severe bleeding that could be life-threatening. Moreover, even if you suffer a slight injury, such as a small cut from shaving, you may bruise easily and the bleeding may take longer to stop than usual. Seek immediate medical attention if you have prolonged or excessive bleeding. If you observe blood in the urine or black, tarry stools, you should notify your doctor. Watch out for any symptoms of a stroke, such as sudden weakness or numbness on one or both sides of the body, slurred speech, mental confusion, difficulty walking, dizziness, and unexplained headache. Since stroke is an unusual adverse effect of Plagerine-A 150 Capsule , call your doctor right away if you experience any of these symptoms.
Plagerine-A 150 Capsule is contraindicated in patient who has an allergy to it or any of its ingredients. If you have or have ever had serious liver disease, bleeding in the brain (stroke or transient ischemic attack), stomach ulcers, or bleeding disorders such as hemophilia (disease in which blood does not clot normally), avoid taking Plagerine-A 150 Capsule . If you are pregnant, attempting to conceive, or are breastfeeding, do not take Plagerine-A 150 Capsule .
If you forget to take a dose of Plagerine-A 150 Capsule , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Avoid activities that could increase the risk of bleeding. Take additional care when shaving or brushing your teeth to prevent bleeding. Additionally, you should not use painkillers; nevertheless, if you must take something like ibuprofen for headache, joint pain, back pain, etc., first consult your doctor. This is due to the possibility of a stomach ulcer and bleeding if you take painkillers along with Plagerine-A 150 Capsule . Avoid consuming too much alcohol while using Plagerine-A 150 Capsule as this may irritate your stomach and lead to stomach ulcer also.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - PLA0012

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