Plackrose A-10 Capsule is a combination of blood-thinning agent and cholesterol-lowering agent, primarily used to prevent myocardial infarction (heart attack), stroke or peripheral vascular disease. It is also used to lower abnormally elevated cholesterol or fat levels (hyperlipidaemia or dyslipidaemia) in the body. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). 

Plackrose A-10 Capsule is composed of two medicines, namely: Rosuvastatin and Aspirin. Rosuvastatin belongs to the class of antilipemic (cholesterol-lowering) agents. It works by blocking liver enzymes, causing the liver to make less cholesterol. Rosuvastatin lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with anti-platelet action. It decreases the formation of blood clots by preventing the platelets from clubbing together. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Plackrose A-10 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases. 

Your doctor will advise you how often you take your tablets based on your medical condition. The common side effects of Plackrose A-10 Capsule include increased bleeding tendency, nausea, abdominal pain, headache, constipation, muscle pain, weakness, dizziness and indigestion. These side effects do not occur in everyone using Plackrose A-10 Capsule and may vary individually. If these side effects occur, they resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine of your own. Stopping Plackrose A-10 Capsule may worsen your condition and increase the risk of a future heart attack. Let your doctor know if you are sensitive to rosuvastatin or aspirin and have any kidney/liver diseases, asthma, active bleeding issues (like peptic ulcer, brain haemorrhage), gastrointestinal disorders, diabetes, mental illnesses (memory loss, forgetfulness, amnesia, memory impairment, confusion), and musculoskeletal disorders before starting Plackrose A-10 Capsule . If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Plackrose A-10 Capsule . The patient should inform the doctor if he/she is taking Plackrose A-10 Capsule before any surgery is scheduled or any new medicine is taken.

Plackrose A-10 Capsule is composed of Rosuvastatin and Aspirin. Rosuvastatin is an antilipemic agent (cholesterol-lowering) or HMG-CoA reductase inhibitor. It works by blocking liver enzymes, causing the liver to make less cholesterol. It also lowers the bad cholesterol (low-density lipoprotein or LDL) levels and increases good cholesterol levels (high-density lipoprotein or HDL) in the blood. Rosuvastatin reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). Aspirin is a non-steroidal anti-inflammatory (NSAID) and anti-platelet drug that decreases blood clot's formation by preventing the platelets from clubbing together. It is also used in heart-related revascularization procedures (provision of new blood supply to a body part), such as coronary artery bypass graft to improve the blood flow through the revascularized area. Plackrose A-10 Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke and other peripheral vascular diseases.

• Nausea
• Abdominal Pain
• Headache
• Constipation
• Muscle Pain
• Weakness
• Dizziness
• Increased Bleeding Tendency
• Indigestion

Before taking Plackrose A-10 Capsule , let your doctor know if you have a history of liver and kidney diseases or allergic reactions to aspirin and rosuvastatin. If you are at risk of internal bleeding (bleeding inside any tissues, organs or joints of your body), a recent injury/surgery or a planned surgery (including dental) in the next few days, coagulation disorders, such as haemophilia and thrombocytopenia and active bleeding issues (peptic ulcer, brain haemorrhage), please inform your doctor before starting the medicine. If you are pregnant, planning to conceive or breastfeeding, it is essential to seek medical advice before starting Plackrose A-10 Capsule . Do not drive or operate machinery if you experience dizziness or drowsiness while using Plackrose A-10 Capsule . Please do not consume alcohol since it may worsen the side effects like dizziness and increased blood pressure. Plackrose A-10 Capsule is not recommended for children below the age of 16 years. 

Drug-Drug Interaction: Plackrose A-10 Capsule may interact with blood thinners (warfarin), gout medicines (probenecid), anti-cancer or anti-arthritis drug (methotrexate), anti-platelet drugs (clopidogrel), antidepressants (lithium, sertraline), immune-related drugs (cyclosporine, tacrolimus), anti-epilepsy drug (valproate, phenytoin), pain killers (naproxen, ibuprofen), anti-diabetic drugs (insulin glargine), blood pressure medicines (lisinopril), cholesterol-lowering drugs (fenofibrate), antacids and oral contraceptives.

Drug-Food Interaction: Limit alcohol intake since it may cause a rise in the blood pressure leading to heart diseases. Avoid fatty foods to help control your cholesterol and triglyceride levels. Caffeine may have minor interactions with Aspirin in Plackrose A-10 Capsule .

Drug-Disease Interaction: Plackrose A-10 Capsule should be cautiously used under a doctor's guidance if you have liver, kidney diseases, active bleeding disorders, asthma, gastrointestinal bleeding disorders, diabetes, musculoskeletal disorder (myopathy) and viral infections.

• WARFARIN
• PROBENECID
• METHOTREXATE
• CLOPIDOGREL
• LITHIUM
• SERTRALINE
• CYCLOSPORINE
• TACROLIMUS
• VALPROATE
• PHENYTOIN
• NAPROXEN
• IBUPROFEN
• INSULIN GLARGINE
• LISINOPRIL
• FENOFIBRATE

• Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Plackrose A-10 Capsule .

• Low cholesterol diet and regular exercise regime are found to complement treatment with Plackrose A-10 Capsule effectively. 

• Keep your cholesterol and triglyceride levels under control.

• Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.

• The high-fat meal should be avoided as it may further increase the risk of a heart attack instead of eating heart-healthy foods.

• Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.

• Keep a check on your weight and exercise regularly to keep your heart healthy.

• Your doctor also guides you on noticing and managing the early symptoms of detecting heart diseases. 

• Please consult your doctor if Plackrose A-10 Capsule needs to be discontinued before undergoing a dental procedure or any surgery. The doctor might ask you to stop taking Plackrose A-10 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

• Monitoring your heart health with occasional ECG will be helpful.

• Please keep a check on your cholesterol levels (HDL, LDL) in blood with timely blood examinations.

Heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. Heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Stroke occurs when a blockage of blood supply to part of the brain prevents brain tissues from getting enough oxygen and nutrients.

Hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol.