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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST

Placida Tablet is a combination medicine used in the treatment of depression, anxiety and asthenia. This medicine works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood, thereby helps treat conditions like psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia, menopausal depression, and depression in alcoholics and drug addicts.

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Manufacturer/Marketer

Mankind Pharma Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Placida Tablet

Placida Tablet is primarily used to treat psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia, menopausal depression, and depression in alcoholics and drug addicts. Depression is a mood disorder that affects a person's daily life and is described as feelings of sadness, loss, or anger. These symptoms may interfere with daily activities and affect the quality of life.

Placida Tablet contains Flupentixol and Melitracen. Flupentixol is an antipsychotic medication that works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen is a tricyclic antidepressant that raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression. Thus, Placida Tablet effectively treats various forms of depression and anxiety.

Take Placida Tablet as prescribed. Your doctor will decide the dose and duration based on your medical condition. Common side effects of Placida Tablet  include insomnia, restlessness, agitation, dizziness, tremor, dry mouth, constipation, accommodation disorder and fatigue. If any of these side effects persist or worsen, contact your doctor immediately. 

Do not use Placida Tablet if you are allergic to any of the components. Seek medical advice if you are pregnant, planning to get pregnant, or breastfeeding. Do not consume alcohol while using Placida Tablet , as there may be an interaction. Placida Tablet is not recommended for excitable or overactive patients since its activating effect may exaggerate these characteristics. The safety and efficacy of Placida Tablet in children have not been established. Keep your doctor informed about your medical condition and medications to rule out any negative effects or interactions.

Uses of Placida Tablet

Treatment of Depression, anxiety and asthenia

Medicinal Benefits

Placida Tablet contains Flupentixol and Melitracen. Placida Tablet is used to treat psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia (abnormal physical weakness), menopausal depression, depression in alcoholics and drug addicts. Flupentixol is an antipsychotic medication. It works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen is a tricyclic antidepressant that raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression.

Directions for Use

Take Placida Tablet as prescribed by your doctor. Swallow the tablet as a whole with a glass of water. Do not crush, break or chew the tablet.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Placida Tablet

  • Insomnia
  • Restlessness
  • Agitation
  • Dizziness
  • Tremor
  • Dry Mouth
  • Constipation
  • Accommodation Disorder (problem with focusing)
  • Fatigue

Drug Warnings

Do not use Placida Tablet if you are allergic to any of the components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Let your doctor know if you have circulatory collapse (specific failure of the blood circulation), depressed level of consciousness due to any cause (e.g. intoxication with alcohol, opiates or barbiturates), untreated narrow-angle glaucoma, coma, blood disorders, phaeochromocytoma (a small vascular tumour), recent myocardial infarction, any degree of atrioventricular block or disorders of cardiac rhythm and coronary artery insufficiency. Concomitant treatment of Placida Tablet with MAOIs (monoamine oxidase inhibitors) is contraindicated as it may cause serotonin syndrome (a combination of symptoms, possibly including confusion, agitation, tremor, hyperthermia and myoclonus). Therefore, do not take Placida Tablet if you are taking MAOIs or have taken them in the past 14 days.

Drug Interactions

Drug-Drug Interactions:  Placida Tablet may interact with MAO inhibitors (isocarboxazid, phenelzine), barbiturates (pentobarbital, phenobarbital), CNS depressants (diazepam, clonazepam, alprazolam), and neuroleptics (thioridazine, chlorpromazine).

Drug-Food Interactions: Limit or avoid the consumption of alcohol.

Drug-Disease Interactions: Placida Tablet should not be used in patients with circulatory collapse (specific failure of the blood circulation), depressed level of consciousness, untreated narrow-angle glaucoma, coma, blood disorders, phaeochromocytoma (a small vascular tumour), recent myocardial infarction, any degree of atrioventricular block or disorders of cardiac rhythm and coronary artery insufficiency.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • PENTOBARBITAL
  • PHENOBARBITAL
  • DIAZEPAM
  • CLONAZEPAM
  • ALPRAZOLAM
  • THIORIDAZINE
  • CHLORPROMAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly attend treatment sessions.
  • Meditation and yoga help to relieve stress.
  • Maintain a consistent sleep schedule to increase the amount and quality of sleep you obtain.
  • Include omega-3 fatty acid-rich foods like fish, nuts, fresh fruits and vegetables, and olive oils in your diet.
  • Amino acids are the building blocks of neurotransmitters. Include foods high in amino acids, including meat, dairy products, and some fruits and vegetables, as they aid in maintaining neurotransmitters.
  • Complex carbs such as whole grains, legumes, spinach, broccoli, oranges, and pears aid in the stimulation of serotonin (a feel-good neurotransmitter).
  • Exercising helps the body's natural antidepressant synthesis. It also aids in stress relief, mood enhancement, self-esteem enhancement, and comfortable sleep.
  • Avoid smoking and drinking alcohol.
  • Learn about your medical condition, be aware of the risk factors, and stick to your doctor's treatment plan.

Special Advise

While using this medication, strictly follow your doctor's recommendations. Even if you feel better, do not reduce or discontinue your medicine on your own. This may aggravate your condition.

Disease/Condition Glossary

Depression: It is a mood condition defined by a continuous feeling of unhappiness, dissatisfaction, hopelessness, anger or loss that interferes with a person's daily activities. Depression can also have an impact on some chronic health issues and relationships. Neurotransmitters such as serotonin, dopamine, and noradrenaline levels drop in this illness, resulting in depressive symptoms. The specific aetiology of depression is unknown; however, it may be linked to mental health issues, family history, drug use, trauma, and physiological diseases. Depression can be treated with medications and psychotherapy.

Anxiety: Anxiety is a state of uneasiness that can range from mild to severe. Anxiety is a normal emotion. However, some people struggle to keep their fears in control. Their worry is more persistent and frequently interferes with their daily life. Anxiety is the primary symptom of several disorders, including panic disorder, phobias (such as agoraphobia or claustrophobia), post-traumatic stress disorder (PTSD), and social anxiety disorder (social phobia).

Asthenia: It is a condition characterised by a lack of energy, strength, and physical or mental weakness which can affect certain body parts or the entire body.

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Alcohol

Caution

It is not safe to drink alcohol while taking this medication.

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Pregnancy

Caution

Placida Tablet should be used in pregnant women only if clinically necessary, and the benefits exceed the risks. Due to the potential for neonatal withdrawal symptoms, the therapy should be discontinued 14 days before delivery by gradually decreasing the dosage.

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Breast Feeding

Caution

No significant research has been conducted on the use of Placida Tablet in breastfeeding/nursing mothers. Please consult your doctor.

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Driving

Caution

Placida Tablet may cause drowsiness. Avoid driving or operating machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have any concerns about the usage of Placida Tablet in patients with liver disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns about the usage of Placida Tablet in patients with kidney disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Placida Tablet is not recommended in children under 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - PLA0031

Author Details

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FAQs

Placida Tablet is used to treat psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia, menopausal depression, and depression in alcoholics and drug addicts.
Placida Tablet contains Flupentixol and Melitracen. Flupentixol works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression. Thus, Placida Tablet effectively reduces the symptoms of depression.
Placida Tablet should not be abruptly discontinued since this may worsen your symptoms. Consult your doctor if you experience any difficulty while taking Placida Tablet .
Placida Tablet is contraindicated for patients who have had a recent myocardial infarction, atrioventricular block of any degree, coronary artery insufficiency, or cardiac rhythm abnormalities.
Placida Tablet works by acting on the brain's neurotransmitters to help regulate mood more effectively. This makes you feel energetic and thus helps treat asthenia.
Placida Tablet works by boosting the serotonin level of a neurotransmitter in the brain. The higher the serotonin levels, the better the brain communicates. Thus, Placida Tablet eases anxiety symptoms.

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