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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:21 PM IST
Pilorute Cream is used to treat anal fissures and haemorrhoids (piles). It promotes healing, decreases the sensation of pain and lowers inflammation, irritation and discomfort. In some cases, this medicine may cause side effects such as burning sensation, irritation, itching and redness at the site of application. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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About Pilorute Cream

Pilorute Cream belongs to the group of medicines called anorectal preparations used to treat anal fissures and haemorrhoids (piles). Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain and bleeding. An anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Pilorute Cream relieves pain, inflammation, discomfort and itching associated with piles and anal fissures.
 
Pilorute Cream contains Calcium dobesilate (vasoprotective agent), Hydrocortisone (steroid), Lidocaine (local anaesthetic), Troxerutin (vasoprotective agent), Zinc oxide (antiseptic) and Phenylephrine (decongestant). Calcium dobesilate and Troxerutin promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone helps in reducing itching, redness and swelling due to piles. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Pilorute Cream provides relief from pain and discomfort due to piles and anal fissures.
 
You are advised to use Pilorute Cream for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the site of application. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Do not use Pilorute Cream if you had a skin reaction or irritation to any steroid medicine. Consult your doctor before using Pilorute Cream if you are pregnant or breastfeeding. Do not use Pilorute Cream for longer durations unless prescribed by your doctor. If your condition does not improve despite using Pilorute Cream for 2-4 weeks, please consult your doctor. Do not use Pilorute Cream over a large area or use tight-fitting diapers/plastic pants unless directed by your doctor. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Pilorute Cream

Treatment of Piles and anal fissures.

Medicinal Benefits

Pilorute Cream is a combination of six drugs, namely: Calcium dobesilate, Hydrocortisone, Lidocaine, Troxerutin, Zinc oxide and Phenylephrine. Pilorute Cream belongs to the group of medicines called anorectal preparations used to treat anal fissures and haemorrhoids (piles). Calcium dobesilate and Troxerutin are vasoprotective agents that promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone is a steroid which helps in reducing itching, redness and swelling due to piles. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine is a decongestant that decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Pilorute Cream provides relief from pain, inflammation, discomfort, and itching associated with piles and anal fissures.

Directions for Use

Clean and dry the affected area. Take a pea-sized amount onto the applicator and apply it directly onto the rectal area.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pilorute Cream

  • Burning sensation
  • Irritation
  • Itching
  • Redness 

Drug Warnings

Do not use Pilorute Cream if you are allergic to any of its contents. Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before using Pilorute Cream if you are pregnant or breastfeeding. Do not use Pilorute Cream for longer durations unless prescribed by your doctor. If your condition does not improve despite using Pilorute Cream for 2-4 weeks, please consult your doctor. Do not use Pilorute Cream over a large area or use tight-fitting diapers/plastic pants unless directed by your doctor. 

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat fibre-rich food and drink plenty of fluids. This helps to keep the stools soft.
  • A warm bath helps in easing pain and itching.
  • Keep your bottom dry and clean.
  • Regular exercise is recommended.
  • Avoid or limit alcohol and caffeinated products to prevent constipation.
  • Empty your bowels whenever your body tells you to.
  • Avoid pushing too hard while pooping as it can cause tissue tearing.
  • Include fruits, vegetables and whole wheat grains in your diet.

Disease/Condition Glossary

Piles: Hemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain, and bleeding. Haemorrhoids can be external or internal. Internal haemorrhoids develop within the rectum and anus, whereas external haemorrhoids develop outside the anus region. Piles cause pain, itching and bleeding. They also cause trouble in sitting. Symptoms include itching, irritation and pain around the anus, swelling near the anus region, painful bowel movements and blood in stools.

Anal fissure: Anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Anal fissures generally heal on their own. If the condition lasts for more than 8 weeks, it can be considered chronic. Sometimes surgery may also be needed depending on the condition. Symptoms include tear of skin around the anus region, burning sensation, pain and blood during a bowel movement.

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Alcohol

Caution

It is not known whether Pilorute Cream interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Pilorute Cream can be used by breastfeeding mothers or not.

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Driving

Safe if prescribed

Pilorute Cream usually does not affect your ability to drive.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Pilorute Cream in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Pilorute Cream in patients with kidney impairment.

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Children

Caution

Please consult a doctor regarding the usage of Pilorute Cream in children. Pilorute Cream should be used in children only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - PIL0068

Author Details

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FAQs

Pilorute Cream is used to treat anal fissures and haemorrhoids (piles).
Pilorute Cream is a combination of six drugs, namely: Calcium dobesilate, Hydrocortisone, Lidocaine, Troxerutin, Zinc oxide, and Phenylephrine. Calcium dobesilate and Troxerutin promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone helps in reducing itching, redness and swelling due to piles. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Pilorute Cream relieves pain and discomfort due to piles and anal fissures.
Pilorute Cream contains a steroid; therefore, it should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Pilorute Cream for a few weeks, consult your doctor, he/she may prescribe you an alternate medicine.
Continue using Pilorute Cream for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Pilorute Cream.
No, Pilorute Cream should not be used on the face or any other body parts. It is intended to treat pain and discomfort associated with piles and anal fissures.
The symptoms of anal fissures and piles are similar. However, an anal fissure is a small tear in the mucosa that lines the anus, whereas piles are inflamed and swollen veins in the rectum and anus that cause discomfort, pain and bleeding.
Pilorute Cream may cause a burning sensation of the skin at the site of application as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.
Pilorute Cream may cause side effects such as irritation, redness, itching or burning sensation at the application site. If any of these side effects persist or worsen, please consult your doctor.
Eat a fibre-rich diet, as it can improve the bowel movement. Consume leafy vegetables, whole grains, lentils and fruits. Avoid excessive alcohol consumption and smoking and drink lots of water. Avoid lifting heavy weights as it can put strain on the anal area.
Your doctor will recommend you to make changes in your diet and lifestyle (like enough sleep and plenty of exercises) and sitz bath. In a sitz bath, fill about half the capacity of the tub with warm water and sit in it bare skin to get relief.

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