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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 26, 2024 | 7:07 PM IST
Pexep 20 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. It contains Paroxetine which works by increasing serotonin concentration, thereby regulating mood. This medicine may sometimes cause side effects such as insomnia, dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

PAROXETINE-20MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Pexep 20 Tablet

Pexep 20 Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoria disorder and generalised anxiety disorder. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.

Pexep 20 Tablet contains ‘Paroxetine’, which is a selective serotonin reuptake inhibitor. It works by inhibiting serotonin's reuptake, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders.

Take Pexep 20 Tablet as prescribed. You are advised to take Pexep 20 Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), dizziness, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and sexual disturbances. You are advised to talk to your doctor if the side effects persist or worsen.

Do not take Pexep 20 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Pexep 20 Tablet if you are breastfeeding. Avoid driving or operating machinery as Pexep 20 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Pexep 20 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Pexep 20 Tablet as it may make your symptoms or side-effects worse. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Pexep 20 Tablet

Treatment of Major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

Medicinal Benefits

Pexep 20 Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Pexep 20 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder. Pexep 20 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression and anxiety disorders. Pexep 20 Tablet has fewer unwanted side effects than older antidepressants and helps people recover from depression.

Side Effects of Pexep 20 Tablet

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Sexual disturbances

Directions for Use

Take Pexep 20 Tablet in the morning with food to prevent stomach upset. Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Pexep 20 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days, or if you are taking antipsychotic medicines such as thioridazine or pimozide. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, diabetes, low sodium levels in blood, glaucoma, or are undergoing treatment for severe depression called electro-convulsive therapy. Do not take Pexep 20 Tablet if you are pregnant, as it may cause harm to the foetus. Consult your doctor before taking Pexep 20 Tablet if you are breastfeeding. Avoid driving or operating machinery as Pexep 20 Tablet may cause dizziness, confusion, sleepiness and blurred vision. Pexep 20 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Avoid consumption of alcohol while taking Pexep 20 Tablet as it may make your symptoms or side-effects worse.

Therapeutic Class

PSYCHOTHERAPEUTICS

Drug-Drug Interactions

verifiedApollotooltip
ParoxetineThioridazine
Critical
ParoxetineIsocarboxazid
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

What if I have taken an overdose of Pexep 20 Tablet

Take Pexep 20 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include sleepiness, nausea, vomiting, tremors, dizziness, confusion, fast heart rate, and coma. Other symptoms observed with the overdose are dilation of the pupil, convulsions, irregular heartbeat, high/low blood pressure, aggressive reactions, liver dysfunction, state of unconsciousness, involuntary muscle contractions, rhabdomyolysis (breakdown of muscle tissue), manic reactions, acute kidney failure, urinary retention, and serotonin syndrome. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pexep 20 Tablet as it may make your symptoms or side-effects worse.

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Pregnancy

Unsafe

Pexep 20 Tablet belongs to pregnancy category D. It is not recommended to take Pexep 20 Tablet if you are pregnant or planning for pregnancy as Pexep 20 Tablet might cause foetal harm.

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Breast Feeding

Caution

Pexep 20 Tablet may pass into breastmilk. Consult your doctor before taking Pexep 20 Tablet ; your doctor will decide whether Pexep 20 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery as Pexep 20 Tablet may cause dizziness, confusion, sleepiness and blurred vision.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pexep 20 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - PEX0004

Author Details

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FAQs

Pexep 20 Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.
Pexep 20 Tablet works by inhibiting serotonin's reuptake by nerves, a mood-enhancing chemical messenger in the brain that communicates between brain cells. This increases serotonin concentrations in the nerve synapse, thereby helping in regulating mood.
Do not discontinue Pexep 20 Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually, continue taking Pexep 20 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pexep 20 Tablet ; the doctor may reduce the dose gradually.
Pexep 20 Tablet may cause decreased libido (sex drive), impotence (erectile dysfunction), abnormal ejaculation and problems with orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Pexep 20 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Please consult your doctor before taking Pexep 20 Tablet if you have glaucoma as Pexep 20 Tablet might cause increased pressure in the eye.
Consult your doctor before taking Pexep 20 Tablet if you have diabetes as Pexep 20 Tablet might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Pexep 20 Tablet . Talk to your doctor if your blood sugar levels are unstable.
People taking antidepressants such as Pexep 20 Tablet are more likely at risk of developing suicidal thoughts. Talk to your doctor immediately if you have thoughts of harming or killing yourself.
Consult your doctor before taking tamoxifen (used to treat cancer) along with Pexep 20 Tablet as Pexep 20 Tablet might make tamoxifen less effective.
Pexep 20 Tablet may cause unusual bleeding or bruising such as vomiting blood or passing blood in stools. Therefore, talk to your doctor before taking Pexep 20 Tablet if you have a history of bleeding disorders or if you are taking medicines that might increase the risk of bleeding such as blood thinners (warfarin), anti-psychotics (perphenazine or clozapine), tricyclic antidepressants (clomipramine), or NSAID’s (acetylsalicylic acid, ibuprofen, celecoxib, etodolac, diclofenac, meloxicam).
Pexep 20 Tablet may cause side effects such as nausea, headache, diarrhoea, dry mouth, fatigue (overtiredness), loss of appetite and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.
Yes, bone fractures have been associated with Pexep 20 Tablet .
The risk of serotonin syndrome is increased when Pexep 20 Tablet is taken together with other serotonergic medicines, including tricyclic antidepressants, fentanyl, triptans, tramadol, buspirone, lithium, tryptophan, thioridazine, isocarboxazid, pimozide, intravenous methylene blue, linezolid, amphetamines, procarbazine, phenelzine, selegiline, tranylcypromine and St. John’s Wort.
You may start noticing an improvement in your symptoms after 1-2 weeks of starting the treatment with Pexep 20 Tablet . If you do not see any improvement, do not stop taking Pexep 20 Tablet and consult your doctor. It may take around 4-6 weeks to see the full effects of Pexep 20 Tablet .
No, do not stop taking Pexep 20 Tablet suddenly, without first consulting your doctor. This is a common problem with Pexep 20 Tablet that you may feel your symptoms have worsened initially but the benefits start showing after 1-2 weeks. You must consult your doctor if the worsening does not improve even after 1-2 weeks.
Pexep 20 Tablet is not recommended for children and adolescents below 18 years of age as patients in this age group have an increased risk of experiencing side effects such as aggression, suicidal thoughts, oppositional behavior and anger when they take Pexep 20 Tablet . If you have any concerns regarding this, please discuss with your doctor.
No, do not take Pexep 20 Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Pexep 20 Tablet . However, Pexep 20 Tablet may make tamoxifen less effective and can lead to recurrence of breast cancer.
Yes, you need to be careful while taking Pexep 20 Tablet if you are a diabetic as Pexep 20 Tablet may change your blood sugar levels. Thus, may need dose adjustment of your insulin or antidiabetic medicines. Discuss with your doctor regarding this and monitor your blood sugar levels regularly.
Pexep 20 Tablet is usually considered safe if taken as advised by a doctor. However, it may cause side effects, just like any medication. Discuss with your doctor about your concerns or potential risks before starting Pexep 20 Tablet .
No, Pexep 20 Tablet is not a sleeping pill. Although its calming effect can promote better sleep, its main purpose is to manage depression and anxiety symptoms.
Your doctor determines the best time to take Pexep 20 Tablet . It can be taken with or without food, but follow your doctor's instructions for dosage and timing.
It may take a few weeks for Pexep 20 Tablet to show improvements in your symptoms. Even if you do not see immediate results, it is important to keep taking it as prescribed by your doctor.
Yes, Pexep 20 Tablet helps manage various anxiety disorders such as obsessive-compulsive disorder and panic disorder. It helps reduce anxiety symptoms by restoring the balance of serotonin in the brain.
If you experience any side effects while taking Pexep 20 Tablet , inform your doctor immediately. After analysing your symptoms, they will modify your treatment plan.

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