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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Perindil 4 Tablet 10's belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. It also helps reduce the chances of heart problems such as heart attack and stroke. This medication functions by inhibiting the angiotensin-converting enzyme, which lowers the body's production of angiotensin II, thereby widening the blood vessels and reducing blood pressure. Common side effects include dizziness, weakness, blurred vision, nausea, and cough.
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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-26

About Perindil 4 Tablet 10's

Perindil 4 Tablet 10's is used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Perindil 4 Tablet 10's contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perindil 4 Tablet 10's relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body. 

Take Perindil 4 Tablet 10's as prescribed. Your doctor will advise you on the dosage and duration based on your medical condition. In some cases, you may experience dizziness, headache, weakness, vomiting, and nausea. Most of these side effects of Perindil 4 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own, even if your blood pressure becomes normal; doing so may worsen your condition. Avoid taking Perindil 4 Tablet 10's if you are pregnant or breastfeeding. Perindil 4 Tablet 10's is not recommended for children below 18 years. Perindil 4 Tablet 10's may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Perindil 4 Tablet 10's

Treatment of Hypertension, Heart failure and Prevention of heart attack

Directions for Use

Swallow Perindil 4 Tablet 10's as a whole with water; do not crush or chew it.

Medicinal Benefits

Perindil 4 Tablet 10's is used to treat high blood pressure and heart failure. Additionally, it is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Perindil 4 Tablet 10's contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perindil 4 Tablet 10's allows constricted blood vessels to relax and, therefore, helps lower high blood pressure.

How Perindil 4 Tablet 10's Works

Perindil 4 Tablet 10's contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perindil 4 Tablet 10's relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Perindil 4 Tablet 10's

  • Cough
  • Nausea
  • Dizziness
  • Headache 
  • Vision disturbances
  • Ankle swelling
  • Weakness
  • Vomiting

What if I have taken an overdose of Perindil 4 Tablet 10's

Do not take more than the prescribed dose of Perindil 4 Tablet 10's as it may cause overdose. The symptoms of overdose include sleepiness, dizziness, and pounding heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Perindil 4 Tablet 10's if you are allergic to any of the contents, ACE inhibitors, if you are taking sacubitril, valsartan, or aliskiren. Inform your doctor if you have/had kidney problems, dialysis, heart problems, liver dysfunction, diabetes, dehydration, angioedema, collagen vascular disease, or primary aldosteronism. Consult your doctor if you develop signs of infection or jaundice. Avoid taking Perindil 4 Tablet 10's if you are pregnant or breastfeeding. Perindil 4 Tablet 10's is not recommended for children below 18years. Perindil 4 Tablet 10's may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
PerindoprilAmiloride
Severe

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
How does the drug interact with Perindil 4 Tablet 10's:
Combining Aliskiren with Perindil 4 Tablet 10's can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perindil 4 Tablet 10's with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PerindoprilAmiloride
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Amiloride when taken with Perindil 4 Tablet 10's may cause a hyperkalemia (high potassium levels in blood).

How to manage the interaction:
Although taking amiloride and Perindil 4 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
PerindoprilAlprazolam
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Taking Alprazolam with Perindil 4 Tablet 10's shows additive effects which may increase their efficacy and side effects. Increased Alprazolam levels may alter blood pressure.

How to manage the interaction:
Taking Alprazolam with Perindil 4 Tablet 10's can show additive efficacy, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience signs such as slurred speech, drowsiness, confusion, blurry visions, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
PerindoprilCandesartan
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Taking Perindil 4 Tablet 10's with candesartan can increase the risk of kidney failure, low blood pressure, and high potassium levels.

How to manage the interaction:
Although taking Perindil 4 Tablet 10's and Candesartan together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
PerindoprilPotassium citrate
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Taking Potassium citrate with Perindil 4 Tablet 10's can cause hyperkalemia(a high level of the electrolyte potassium in the blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Perindil 4 Tablet 10's with Potassium citrate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
PerindoprilMipomersen
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Using Perindil 4 Tablet 10's together with mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Perindil 4 Tablet 10's with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PerindoprilPotassium acetate
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Taking potassium acetate with Perindil 4 Tablet 10's can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Perindil 4 Tablet 10's and Potassium acetate together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilPotassium iodide
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Combining Potassium Iodide with Perindil 4 Tablet 10's can cause hyperkalemia(high potassium levels in blood) which can increase the risk the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Perindil 4 Tablet 10's with Potassium iodide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilOlmesartan medoxomil
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Coadministration of Olmesartan medoxomil with Perindil 4 Tablet 10's may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking olmesartan medoxomil together with Perindil 4 Tablet 10's may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
PerindoprilTeriflunomide
Severe
How does the drug interact with Perindil 4 Tablet 10's:
Using Teriflunomide together with Perindil 4 Tablet 10's can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Perindil 4 Tablet 10's and Teriflunomide, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Perindil 4 Tablet 10's with potassium-containing foods can increase the risk of hyperkalemia (high potassium levels in the blood). Avoid moderately high or high potassium dietary intake with Perindil 4 Tablet 10's, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.

  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES AND ACE INHIBITORS

Perindil 4 Tablet 10's Substitute

Substitutes safety advice
  • Coversyl 4 mg Tablet 10's

    17.78per tablet
  • Perindosyl-4Mg Tablet 10'S

    by AYUR

    11.25per tablet
  • Rindopril 4mg Tablet

    9.81per tablet
  • Zimpril 4 Tablet

    7.65per tablet
  • Rindopril 4 Tablet

    11.52per tablet
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Alcohol

Unsafe

Alcohol may enhance the hypotensive (low blood pressure) effect of Perindil 4 Tablet 10's. It may also cause increased dizziness. For better advice, you should consult your doctor if you can take Perindil 4 Tablet 10's with alcohol.

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Pregnancy

Unsafe

Avoid taking Perindil 4 Tablet 10's if you are pregnant, especially if you are more than 3months pregnant as it may cause harm to the developing fetus. Consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Use of Perindil 4 Tablet 10's is not recommended during the breastfeeding.

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Driving

Caution

Perindil 4 Tablet 10's may cause blurry vision, dizziness or weakness. Drive or operate machinery only if you are alert.

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Liver

Caution

Rare elevation in liver enzymes (like bilirubin) has been observed while taking Perindil 4 Tablet 10's, so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Perindil 4 Tablet 10's to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Perindil 4 Tablet 10's should be given with precaution in hemodialysis condition.

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Children

Unsafe

The safety and effectiveness of Perindil 4 Tablet 10's in children below 18years have not been established.

FAQs

Perindil 4 Tablet 10's is used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart.
Perindil 4 Tablet 10's relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body.
It is advised to continue taking Perindil 4 Tablet 10's even after your blood pressure is under control or becomes normal as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.
Perindil 4 Tablet 10's might alter potassium levels. Therefore inform your doctor if you are taking food rich in potassium, potassium-containing salt substitutes or over-the-counter potassium supplements.
Light-headedness could be a side-effect of Perindil 4 Tablet 10's. It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Perindil 4 Tablet 10's are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Inform your doctor if you are diabetic as Perindil 4 Tablet 10's may cause hypoglycaemia (low blood glucose levels). Regular monitoring of blood sugar levels is advised.
Perindil 4 Tablet 10's belongs to the antihypertensive medicines used to treat high blood pressure.
To manage high blood pressure, take your medication as prescribed and make healthy lifestyle choices. Eat a balanced diet, exercise regularly, limit sodium and alcohol, and manage stress. These changes can help lower your blood pressure and improve your overall health.
No, you should not discontinue Perindil 4 Tablet 10's without consulting your doctor. Even if you feel better, you should continue to take the medication as directed. Stopping abruptly might result in a sudden rise in blood pressure, leading to significant health issues. Your doctor will assess whether reducing or discontinuing your medication is safe based on your specific condition and blood pressure measurements.
Yes, Perindil 4 Tablet 10's may cause dizziness. This is a usual adverse effect, particularly when first starting the medicine. However, discomfort usually fades away after a few days or weeks as your body becomes used to the medicine. If the problem persists, visit your doctor.
The ideal time to take Perindil 4 Tablet 10's is typically in the morning. This helps to keep your blood pressure steady throughout the day. However, depending on your specific needs and medications, your doctor may recommend a different time. It's critical to follow their exact directions.
Yes, Perindil 4 Tablet 10's can raise potassium levels in the blood. This is because it inhibits the function of angiotensin II, a chemical that ordinarily causes the kidneys to retain sodium while losing potassium. If your potassium levels grow too high, you may experience major health problems, such as irregular heartbeat. Your doctor will likely order specific blood tests to monitor your potassium levels. If your potassium levels are too high, your doctor may change your perindopril dose or prescribe a medicine to help lower them.
Dry cough is a common side effect of Perindil 4 Tablet 10's. It's often a bother but usually resolves on its own within a few weeks. Talk to your doctor if the cough becomes severe or interferes with your daily activities. They may be able to adjust your dosage or prescribe a different medication.
There's no clear evidence to suggest that taking perindopril reduces fertility in either men or women. Seek medical attention if you have any concerns regarding this.
No, if you become pregnant while taking perindopril, inform your doctor immediately. The medication can harm the developing fetus.
Perindil 4 Tablet 10's may interact with other drugs, increasing or lowering their efficacy or producing adverse effects. It is critical to tell your doctor about all medications you are taking, including over-the-counter treatments, herbal supplements, and prescription prescriptions.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Alcohol may enhance the hypotensive (low blood pressure) effect of Perindil 4 Tablet 10's. It may also cause increased dizziness. For better advice, you should consult your doctor if you can take Perindil 4 Tablet 10's with alcohol.
The symptoms of overdose include sleepiness, dizziness, and a pounding heartbeat. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.
No, Perindil 4 Tablet 10's should be swallowed whole with a glass of water. Crushing or chewing it may affect the medication's absorption.
Perindil 4 Tablet 10's can sometimes affect kidney function. Regular monitoring of kidney function is important, especially if you have pre-existing kidney problems.
Yes, Perindil 4 Tablet 10's can help reduce the risk of heart attack and stroke in people with high blood pressure or other cardiovascular risk factors.
Store Perindil 4 Tablet 10's in a dry place, away from heat and direct sunlight. Keep them out of the reach of children and pets.
Your doctor will determine the appropriate frequency of follow-up appointments based on your individual needs and blood pressure control. Regular monitoring is essential to ensure the medication is working effectively.
Yes, adopting a healthy lifestyle can enhance the benefits of Perindil 4 Tablet 10's. This includes maintaining a balanced diet, exercising regularly, managing stress, and limiting alcohol consumption.

Country of origin

India

Manufacturer/Marketer address

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001
Other Info - PER0535

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