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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Peribite M 50 Tablet 10's is used for the management and treatment of type 2 diabetes, especially in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. It contains Metformin and Acarbose, which works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. Also, it slows down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose. Thereby, slows down and reduces the absorption of sugar into the blood after every meal. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Spectra Therapeutics Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Peribite M 50 Tablet 10's

Peribite M 50 Tablet 10's is primarily used for the management and treatment of type 2 diabetes, especially in people whose sugar levels are too high and cannot be controlled by dieting and exercising alone. Type 2 diabetes is a condition which occurs when there is either less insulin or available insulin is not properly utilized by our body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of total diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Peribite M 50 Tablet 10's contains two medicines namely: 'Metformin' and 'Acarbose'. Metformin is a 'biguanides' that works by reducing the amount of blood sugar released in the bloodstream by the liver, thereby making the body respond in a better way to insulin. On the other hand, 'Acarbose; is an ‘alpha glucosidase inhibitor’ which works by slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose thereby slowing and reducing the absorption of sugar into the blood after every meal.

Take Peribite M 50 Tablet 10's as prescribed. Your doctor will recommend how often you need to take Peribite M 50 Tablet 10's based on your medical condition. Some people may experience some unpleasant effects at the beginning of the treatment with Peribite M 50 Tablet 10's such as increased wind, rumbling in the stomach and abdominal cramps, which happen as the body adjusts to the new medicine. However, if these unpleasant effects continue for more than days or become severe or you experience diarrhoea, then seek medical attention immediately.

If you are hypersensitive to any of the components present in these medicines, then please tell your doctor before taking this drug. Peribite M 50 Tablet 10's is not recommended for use in children. If you are pregnant, breastfeeding, or planning to be pregnant, then tell your doctor before they prescribe this medicine to you. Limit your alcohol consumption with Peribite M 50 Tablet 10's, as alcohol may cause a rapid increase or decrease in blood sugar levels.

Uses of Peribite M 50 Tablet 10's

Treatment of Type 2 diabetes mellitus.

Medicinal Benefits

Peribite M 50 Tablet 10's is an anti-diabetic drug indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and are not even controlled by diet and exercise alone. Peribite M 50 Tablet 10's consists of Acarbose and Metformin, used for controlling raised blood sugar in type 2 diabetes patients. Acarbose is an ‘alpha-glucosidase inhibitor’ responsible for the inhibition of intestinal enzymes that delay the digestion of carbohydrates taken through the meal. Metformin belongs to a group of medications called 'biguanides' that works by improving glucose tolerance in patients dealing with type 2 diabetes. It also reduces the intestinal absorption of glucose and thus increases the utilization of glucose. Together, they avoid the additional risk of disease associated with diabetes, such as eye problems (diabetes retinopathy), kidney damage (diabetic nephropathy), nerve damage (diabetic neuropathy), diabetic foot ulcers, delayed wound healing and other diabetic complications.

Directions for Use

Take Peribite M 50 Tablet 10's with food or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Peribite M 50 Tablet 10's

  • Flatulence (gas)
  • Abdominal discomfort
  • Stomach pain
  • Diarrhea

Drug Warnings

Tell your doctor if you have kidney disease, high ketone levels in blood or urine,  heart disease, congestive heart failure, liver disease or you are using insulin, or other oral diabetes medications. A person should keep taking Peribite M 50 Tablet 10's even if they are feeling that their blood sugar levels are under control as it may again spike the level of sugar in the blood. Try to take a dose at the right time so that you did not forget to take a dose, ask your doctor for advice. It may be possible that a person may develop lactic acidosis, which happens due to the overproduction of lactic acid in the blood so tell your doctor if you are noticing any symptoms of it. You should take small frequent meals and don't fast while being treated with Peribite M 50 Tablet 10's. Try to notice if you are developing the symptoms of hypoglycemia (low blood sugar) like sweating, dizziness,  dry mouth, dry skin, palpitations, shivering, intense thirst, frequent urination, etc. If you notice any of the mentioned symptoms, then immediately take 5-6 candies or honey/sugar and consult with a physician. 
 

Drug Interactions

Drug-Drug Interaction: Peribite M 50 Tablet 10's needs not to be used with other antibiotics (neomycin), heart-related medicines (digoxin), antidiabetic drugs (metformin), drugs used to treat high cholesterol (cholestyramine), and medications for digestive enzymes (lipase, pancreatin, amylase), and intestinal absorbents (charcoal).

Drug- Food Interaction: Peribite M 50 Tablet 10's may interact with household sugar and cause abdominal discomfort and stomach upset. Therefore one should avoid consuming foods rich in sugar. Additionally, avoid alcohol consumption while taking Peribite M 50 Tablet 10's as it may spike the levels of sugar in blood or cause low blood sugar levels.

Drug-Disease Interaction: Persons dealing with ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, severe kidney or liver disorders, diarrhea, bowel pain, vomiting, and weight loss) and large hernia (bulging of a tissue or organ through an unusual opening) in intestine should discuss with a doctor before using Peribite M 50 Tablet 10's.

Drug-Drug Interactions Checker List

  • METFORMIN
  • DIGOXIN
  • NEOMYCIN
  • CHOLESTYRAMINE
  • LIPASE
  • AMYLASE+PAPAIN
  • CHARCOAL
  • PANCREATIN

Habit Forming

No

Diet & Lifestyle Advise

  • A person should engage themself in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.

  • A person should also maintain healthy body weight to avoid obesity or high blood sugar it can increase the risk of the onset of diabetes.

  • A person should take low fat and a low sugar diet. For that replace carbohydrates with whole grains, fruits, and vegetables as carbohydrates changed into sugars leading to high blood sugar levels.

  • Try to avoid potatoes as they are high glycemic foods that increase the risk of high sugar in the blood.

  • A person should limit the consumption of alcohol and quit smoking.

 

Special Advise

You should have Glycated hemoglobin (HbA1C) test every 3 months to check your blood glucose level control.

Disease/Condition Glossary

Type 2 diabetes: It is a chronic or life-long condition in which cells of the body fail to respond to insulin, and in later stages, the body even fails to produce enough amount of insulin. It comprises around 90% of total diabetes cases. This condition makes the body rely on different energy sources in muscles, tissues, and organs. This disease develops gradually, and the early symptoms include constant hunger, lack of energy, fatigue, weight loss, excessive thirst, frequent urination, dry mouth, itchy skin, and blurry vision. Persons who are middle-aged or older are most possibly have type 2 diabetes, so it is also called adult-onset diabetes. The risks of uncontrolled type 2 diabetes include damaged retina of the eyes or blindness, loss of limbs, nerve problems, kidney problems, sexual dysfunction, and increased possibility of heart attack or stroke.

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Alcohol

Unsafe

You are should avoid consuming alcohol with Peribite M 50 Tablet 10's as it may lead to high or low blood sugar levels.

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Pregnancy

Caution

Peribite M 50 Tablet 10's is a Category B pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.

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Breast Feeding

Caution

Avoid nursing your baby while taking Peribite M 50 Tablet 10's as this medicine may pass in breast milk.

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Driving

Safe if prescribed

Peribite M 50 Tablet 10's is safe to take before driving as it does not affect your thinking ability.

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Liver

Caution

Take Peribite M 50 Tablet 10's only after the doctor's prescription, especially if you are dealing with Liver diseases/conditions as your doctor may adjust the dose as required.

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Kidney

Caution

Take Peribite M 50 Tablet 10's after the recommendation of a doctor, especially if you have a history of Kidney diseases/conditions. The dosing strength needs to be adjusted by your doctor as required.

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Children

Unsafe

The use of Peribite M 50 Tablet 10's is unsafe for children below 12 years.

Country of origin

India

Manufacturer/Marketer address

Ff-11-12-13, Narayan Krupa Complex, Bopal Rd, South Bopal, Bopal, Ahmedabad, Gujarat 380058
Other Info - PER0643

Author Details

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FAQs

Peribite M 50 Tablet 10's is used for the management and treatment of type 2 diabetes. It works by reducing the amount of blood sugar released in the bloodstream by the liver and slowing down the action of intestinal enzymes responsible for the digestion of complex sugars/glucose.
The use of Peribite M 50 Tablet 10's is strictly prohibited in persons already taking 'digoxin' for treating heartbeats as it may lead to serious drug interaction. One should tell their doctor. If a person needs to take both medicines together, then they need to consult with their doctor so that their doctor may adjust the dose appropriately to use safely.
Peribite M 50 Tablet 10's is contraindicated in the condition of 'diabetic ketoacidosis' or 'lactic acidosis' as it may lead to overload of acids or ketones in your blood and kidney is unable to remove it leading to sever life threatening conditions.
You should try to take small meals at regular intervals and should not skip your meals as it can help Peribite M 50 Tablet 10's to work more effectively by utilizing glucose in the right manner. Fasting is dangerous for diabetes patient taking Peribite M 50 Tablet 10's as it would lower blood sugar level leading to hypoglycemia.
No, a person should continue taking Peribite M 50 Tablet 10's as much doctor has prescribed for the treatment of type 2 diabetes. You should not stop discontinuing Peribite M 50 Tablet 10's suddenly as it may worsen the symptoms of type 2 diabetes and increase the blood sugar level leading to hyperglycemia.

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