Perfecine Tablet

Perfecine Tablet is used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Perfecine Tablet contains ‘Pirfenidone’, which helps reduce scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helping you breathe better. Perfecine Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Perfecine Tablet if you are pregnant or breastfeeding. Perfecine Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Perfecine Tablet as it could lead to increased dizziness. Perfecine Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Perfecine Tablet is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Perfecine Tablet can help effectively slow the rate of lung function decline by 50%. Perfecine Tablet helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helping you breathe better. Perfecine Tablet helps in slowing down the progress of idiopathic pulmonary fibrosis.

• Nausea
• Tiredness
• Diarrhoea
• Indigestion/Stomach upset
• Loss of appetite
• Headache
• Photosensitivity

Do not take Perfecine Tablet if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Perfecine Tablet if you are pregnant or breastfeeding. Perfecine Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Perfecine Tablet as it could lead to increased dizziness. Perfecine Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions: Perfecine Tablet may interact with an anti-depressant (fluvoxamine), antibiotics (ciprofloxacin, enoxacin, rifampicin), antiarrhythmic (amiodarone, propafenone), antacid (omeprazole).

Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.

Drug-Disease Interactions: Inform your doctor if you have severe hepatic problems or end-stage renal impairment requiring dialysis.

• FLUVOXAMINE
• CIPROFLOXACIN
• ENOXACIN
• RIFAMPICIN
• AMIODARONE
• PROPAFENONE
• OMEPRAZOLE

• Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.

• Exercise moderately. Eat healthily.

• Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.

• Quit smoking.

• Get ample rest.

• Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.

• Lean proteins such as fish, meat, and poultry are the best.

• Hydration is important. Drink plenty of water, herbal tea, and fruit juices.

• Avoid processed and refined foods.

• Your doctor may advise liver function tests prior to the start of the treatment.

• Regular blood tests are advised at the start of treatment with Perfecine Tablet and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Idiopathic pulmonary fibrosis (IPF): Idiopathic pulmonary fibrosis belongs to a group of interstitial lung diseases. It is an irreversible chronic disease marked by a progressive decline in lung function. The tissues in the lungs become inflamed and scarred over time, which makes it difficult to breathe properly. The scar tissue, known as fibrosis, becomes thick /stiff over time, making it hard for the lungs to work efficiently. This causes decreased lung function, which leads to increased breathlessness and coughing. Breathing difficulties can lead to other medical problems. Symptoms of IPF are shortness of breath, persistent dry cough, loss of appetite, weight loss, and rounded and widened tips of the fingers and toes.