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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Pentasa 500 mg Tablet is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Composition :

MESALAZINE-500MG

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Pentasa 500 mg Tablet

Pentasa 500 mg Tablet belongs to a class of drugs called 'anti-inflammatory drugs used to treat ulcerative colitis and Crohn’s disease. Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus.

Pentasa 500 mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Take Pentasa 500 mg Tablet as prescribed. You are advised to use Pentasa 500 mg Tablet for as long as your doctor has recommended it for you based on your medical condition. In some cases, you may experience diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). Most of these side effects of Pentasa 500 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Pentasa 500 mg Tablet if you are allergic to Mesalazine or any other medicines. Pentasa 500 mg Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Pentasa 500 mg Tablet . Avoid taking Pentasa 500 mg Tablet if you have severe kidney failure. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Pentasa 500 mg Tablet immediately and consult a doctor.

Uses of Pentasa 500 mg Tablet

Pentasa 500 mg Tablet is used in the treatment of Ulcerative colitis and Crohn's disease

Medicinal Benefits

Pentasa 500 mg Tablet contains Mesalazine, an anti-inflammatory drug used in the treatment of ulcerative colitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping in reducing inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Pentasa 500 mg Tablet may prevent further episodes of ulcerative colitis.

Side Effects of Pentasa 500 mg Tablet

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Flatulence (gas)

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Mesalazine or any other medicines, please tell your doctor. Pentasa 500 mg Tablet should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Pentasa 500 mg Tablet . Avoid taking Pentasa 500 mg Tablet if you have severe kidney failure. Severe skin reactions such as toxic epidermal necrolysis (skin peeling and blistering) or Stevens-Johnson syndrome (a painful rash that spreads and blisters) can occur in some patients taking Pentasa 500 mg Tablet . Therefore, if you notice any skin reactions while taking Pentasa 500 mg Tablet , please consult a doctor immediately. If you have stomach pain or cramps, severe headache, fever or rash, stop taking Pentasa 500 mg Tablet immediately and consult a doctor. Avoid taking Pentasa 500 mg Tablet if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine.

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Drug-Drug Interactions

verifiedApollotooltip
MesalazineCidofovir
Critical
MesalazineIodamide
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Include olive oil and omega-3 fatty acids. Eat more fibre-rich foods such as fruits and vegetables.
  • Limit dairy intake as your body may develop difficulty digesting certain dairy products when you are affected with Crohn’s disease, which leads to stomach cramps, diarrhoea or stomach upset.
  • Drink plenty of water to prevent dehydration.

Habit Forming

No

How Pentasa 500 mg Tablet Works

Pentasa 500 mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
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Alcohol

Consult your doctor

The interaction of alcohol with Pentasa 500 mg Tablet is unknown. If you have concerns, please discuss them with your doctor before taking Pentasa 500 mg Tablet .

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Pregnancy

Consult your doctor

Pentasa 500 mg Tablet is a Category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before taking Pentasa 500 mg Tablet .

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Breast Feeding

Caution

Pentasa 500 mg Tablet should not be taken by breastfeeding mothers unless advised by the doctor. Granules form of Mesalazine may cause allergic reactions such as diarrhoea in newborn babies after breastfeeding. If this happens, discontinue breastfeeding.

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Driving

Safe

Pentasa 500 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor if you have liver problems before using Pentasa 500 mg Tablet .

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Kidney

Caution

Pentasa 500 mg Tablet should be used with extreme caution in patients with mild to moderate kidney impairment. Avoid taking Pentasa 500 mg Tablet if you have severe kidney impairment.

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Children

Caution

Pentasa 500 mg Tablet is not recommended for children below two years. However, Pentasa 500 mg Tablet should be given to children only if recommended by a doctor.

Country of origin

INDIA

Manufacturer/Marketer address

K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Other Info - PEN0014

Author Details

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FAQs

Pentasa 500 mg Tablet is used to treat Ulcerative colitis and Crohn's disease.
Pentasa 500 mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
You are not recommended to take Pentasa 500 mg Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Pentasa 500 mg Tablet with other medicines.
Yes, Pentasa 500 mg Tablet may cause kidney stones in some patients. It is not necessary for everyone taking Pentasa 500 mg Tablet to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Pentasa 500 mg Tablet to prevent kidney stones.
Pentasa 500 mg Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Pentasa 500 mg Tablet .
Yes, Pentasa 500 mg Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Pentasa 500 mg Tablet to prevent dehydration.

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