Penidure LA 12 Injection belongs to a group of anti-bacterial or antibiotic medicines known as penicillins. Penidure LA 12 Injection is used to treat and prevent a wide range of bacterial infections. It kills the bacteria (germs) which cause infections. Bacterial infections are illnesses or conditions caused by bacterial growth in or on the body.

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine), an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. As a result, the bacterial cell wall is damaged, and the organism dies.

A qualified healthcare professional will administer Penidure LA 12 Injection. During the treatment with Penidure LA 12 Injection, you may observe some common side effects like fungal infection (candidiasis), diarrhoea, feeling sick (nausea) and changes in certain tests and investigation results performed by your doctor. These effects are temporary and resolve gradually with time. If any of these side effects persist, consult your doctor.

Inform your doctor if you are allergic to any medicines or foods. Keep your doctor informed about your health condition and all the medicines used before taking Penidure LA 12 Injection to rule out any side effects. Inform your doctor if you are pregnant, expecting pregnancy or breastfeeding. Do not discontinue or abruptly stop the medication, as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine). It is effective against a wide range of bacterial infections. You can get sick and have your body quickly reproduce with harmful or contagious bacteria. Penidure LA 12 Injection effectively kills the bacteria (germs) which cause infections. Erysipelas (skin infection), syphilis, rheumatic fever, post-streptococcal glomerulonephritis (a specific form of kidney inflammation), erysipelas (skin infection), and tropical infectious diseases of the skin (such as yaws or pinta) treated with it.

• Injection site reactions
• Fungal infection (candidiasis)
• Diarrhoea
• Feeling sick (nausea)
• Abnormal lab investigations

Diarrhoea may occur during antibiotic treatment, including benzylpenicillin benzathine, and may last for several weeks after you discontinue treatment. Contact your doctor right away if you have severe or persistent diarrhoea, or if your stools contain blood or mucus. Treatment with benzylpenicillin benzathine must be discontinued immediately since it can be fatal. Take no drugs that stop or slow down bowel movements. Penidure LA 12 Injection may alter test results with certain medical tests. Tell your doctor before undergoing those tests that you are using Penidure LA 12 Injection.

Drug-Drug Interactions: Penidure LA 12 Injection interacts with certain vaccines (e.g. BCG vaccine, Cholera vaccine, typhoid vaccine), immunosuppressant medication (e.g. mycophenolic acid, mycophenolate mofetil).

Drug-Food Interactions: Avoid consumption of alcohol while receiving Penidure LA 12 Injection as it can cause serious side effects. 

Drug-Disease Interactions: Penidure LA 12 Injection interacts with various disease conditions, including colitis (inflammation of the colon) and asthma/allergies.

• BCG VACCINE
• CHOLERA VACCINE
• TYPHOID VACCINE
• MYCOPHENOLIC ACID
• MYCOPHENOLATE MOFETIL

• It would be best to take probiotics after taking the full course of Penidure LA 12 Injection to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after taking an antibiotic course. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
• Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Penidure LA 12 Injection.
• Avoid intake of alcoholic beverages with Penidure LA 12 Injection as it can make you dehydrated and affect your sleep. As a result, your body may find it more difficult to assist Penidure LA 12 Injection in warding off infections.

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with a weak immune system or who are taking immunosuppressive medicine are more prone to bacterial infection.