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  3. Penidure LA 12 Injection

Penidure LA 12 Injection, Pack of 1 Injection
Penidure LA 12 Injection, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Penidure LA 12 Injection is used to treat and prevent a wide range of bacterial infections. It contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine), an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. As a result, the bacterial cell wall is damaged, and the organism dies. Common side effects of Penidure LA 12 Injection are fungal infection (candidiasis), diarrhoea, feeling sick (nausea) and changes in specific tests and investigation results performed by your doctor.

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Synonym :

BENZYLPENICILLIN BENZATHINE, BENZATHINE PENICILLIN, PENICILLIN G BENZATHINE

Composition :

BENZATHINE BENZYLPENICILLIN-1200000IU

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Penidure LA 12 Injection

Penidure LA 12 Injection belongs to a group of anti-bacterial or antibiotic medicines known as penicillins. Penidure LA 12 Injection is used to treat and prevent a wide range of bacterial infections. It kills the bacteria (germs) which cause infections. Bacterial infections are illnesses or conditions caused by bacterial growth in or on the body.

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine), an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. As a result, the bacterial cell wall is damaged, and the organism dies.

A qualified healthcare professional will administer Penidure LA 12 Injection. During the treatment with Penidure LA 12 Injection, you may observe some common side effects like fungal infection (candidiasis), diarrhoea, feeling sick (nausea) and changes in certain tests and investigation results performed by your doctor. These effects are temporary and resolve gradually with time. If any of these side effects persist, consult your doctor.

Inform your doctor if you are allergic to any medicines or foods. Keep your doctor informed about your health condition and all the medicines used before taking Penidure LA 12 Injection to rule out any side effects. Inform your doctor if you are pregnant, expecting pregnancy or breastfeeding. Do not discontinue or abruptly stop the medication, as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Uses of Penidure LA 12 Injection

Treatment of Bacterial infections

Directions for Use

A qualified healthcare professional will administer it. Do not self-administer.

Medicinal Benefits

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine). It is effective against a wide range of bacterial infections. You can get sick and have your body quickly reproduce with harmful or contagious bacteria. Penidure LA 12 Injection effectively kills the bacteria (germs) which cause infections. Erysipelas (skin infection), syphilis, rheumatic fever, post-streptococcal glomerulonephritis (a specific form of kidney inflammation), erysipelas (skin infection), and tropical infectious diseases of the skin (such as yaws or pinta) treated with it.

How Penidure LA 12 Injection Works

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine), an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. As a result, the bacterial cell wall is damaged, and the organism dies.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Penidure LA 12 Injection

  • Injection site reactions
  • Fungal infection (candidiasis)
  • Diarrhoea
  • Feeling sick (nausea)
  • Abnormal lab investigations

What if I have taken an overdose of Penidure LA 12 Injection

As Penidure LA 12 Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Diarrhoea may occur during antibiotic treatment, including benzylpenicillin benzathine, and may last for several weeks after you discontinue treatment. Contact your doctor right away if you have severe or persistent diarrhoea, or if your stools contain blood or mucus. Treatment with benzylpenicillin benzathine must be discontinued immediately since it can be fatal. Take no drugs that stop or slow down bowel movements. Penidure LA 12 Injection may alter test results with certain medical tests. Tell your doctor before undergoing those tests that you are using Penidure LA 12 Injection.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Penidure LA 12 Injection to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after taking an antibiotic course. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Penidure LA 12 Injection.
  • Avoid intake of alcoholic beverages with Penidure LA 12 Injection as it can make you dehydrated and affect your sleep. As a result, your body may find it more difficult to assist Penidure LA 12 Injection in warding off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

Avoid consumption of alcohol while on treatment with Penidure LA 12 Injection.

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Pregnancy

Safe if prescribed

Penidure LA 12 Injection can be used during pregnancy after appropriate diagnosis and careful consideration of the benefits and risks by the prescribing doctor

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Breast Feeding

Caution

Mothers receiving Penidure LA 12 Injection should discard their breast milk while on therapy. They can start breastfeeding again 24 hours after completion of treatment.

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Driving

Safe if prescribed

Penidure LA 12 Injection can significantly influence the ability to drive and use machines. So, do not drive or operate machinery until you are alert.

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Liver

Caution

Inform your doctor if you have liver problems before taking Penidure LA 12 Injection.

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Kidney

Caution

Dose adjustments are necessary in patients with impaired kidney function. Inform your doctor if you have kidney problems. Your doctor will adjust the dose based on your health condition.

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Children

Safe if prescribed

Penidure LA 12 Injection can be given safely to children; your doctor will decide the dose based on the age and condition of your child.

FAQs

What is the use of Penidure LA 12 Injection?

Penidure LA 12 Injection contains Benzathine Benzylpenicillin (also known as Benzylpenicillin Benzathine or Benzathine penicillin or Penicillin G benzathine), an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and it leads to bacteria death.

Yes, Penidure LA 12 Injection can be used to treat rheumatic fever.

No, this is an antibiotic medication. You need to complete the full course even if you start to feel better to prevent the return of infection and resistance to Penidure LA 12 Injection.

Penidure LA 12 Injection does not work against viral infection. So, it should not be taken to treat the common cold or cough. Consult your doctor if you have these symptoms.

As Penidure LA 12 Injection is injectable, it can start working soon after administration. However, Penidure LA 12 Injection may take a few days to kill the bacteria and prevent the further spread of infection.

Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea, as it may help increase the number of good bacteria in the intestine, which aids in digestion.

Consult your doctor before taking Penidure LA 12 Injection during pregnancy. Penidure LA 12 Injection can be used during pregnancy after careful consideration of the benefits and risks by the doctor.

Yes, Penidure LA 12 Injection can cause allergic reactions rarely. Symptoms of an allergic reaction may include rash, hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, consult your doctor.

Inform your doctor if you have allergies to Penidure LA 12 Injection, if you have any pre-existing conditions like liver or kidney problems, heart conditions, or any other chronic illnesses. Also, let your doctor know if you are breastfeeding, pregnant or planning pregnancy.

Penidure LA 12 Injection is given slowly and deeply into a muscle, which can cause pain and discomfort. However, if the pain persists, inform your doctor.

Penidure LA 12 Injection will be administered intramuscularly (IM) usually by a qualified medical expert. Do not self-administer.

No, you should not use Penidure LA 12 Injection if the solution looks discoloured. A discoloured solution may indicate contamination, which can make the Penidure LA 12 Injection less effective and potentially cause additional side effects.

The common side effects of Penidure LA 12 Injection are injection site reactions, fungal infection (candidiasis), diarrhoea, and feeling sick (nausea). If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.
Other Info - PEN0009

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:31 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.11043.pdf
  2. https://www.drugs.com/drug-interactions/penicillin-g-benzathine.html
  3. https://www.unitedpharmacies.md/Pencom-Injection-Benzathine-Penicillin.html
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